DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Adgf-B and Adal

DIOPT Version :9

Sequence 1:	NP_649006.2	Gene:	Adgf-B / 39975	FlyBaseID:	FBgn0036751	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	XP_011238139.1	Gene:	Adal / 75894	MGIID:	1923144	Length:	396	Species:	Mus musculus

Alignment Length:	298	Identity:	75/298 - (25%)
Similarity:	117/298 - (39%)	Gaps:	68/298 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   239 NALKEFAEDGVQYLELRSLLPPLYCIDGDMLTIRDTVAIYNSELERFRADHPDFIGSKLIYAPLR 303
            :.:||||:|||:|||||| .|......|  :|.:..|......:::.:.::.|.....|:....|
Mouse    88 DVIKEFADDGVKYLELRS-TPREENATG--MTRKTYVESVLEGIKQCKQENLDIDVRYLMAIDRR 149

  Fly   304 GVEPSVVEQYVKTAVELNKEF----PNFMVGFDLVGQEELGRPLIDFVEPLLKMPE-HINFYFHA 363
            | .|::..:    .|||.|||    .|.::|.||.|...:|: ..||:||||:..: .:....|.
Mouse   150 G-GPTIARE----TVELAKEFFLSTENTVLGLDLSGDPTIGQ-ANDFLEPLLEAKKAGLKLALHL 208

  Fly   364 GETNWFGSPIDENLVDAIL-LGTKRIGHG--------------------------------YAIT 395
            .|.     |..|.....:| |...|||||                                |...
Mouse   209 AEI-----PNREKENQMLLSLLPDRIGHGTFLSASEAGALDQVDFVRQHQIPLVLEANAELYMCR 268

  Fly   396 KHPMMMR--------LAKLLGIAIEVCPVSNQVLQLGVDYRNHPAALLLAANVPIVISSDDPSFW 452
            ..|:::|        .::::.|..|:|..||...|....|..|......:...|.||.:||...:
Mouse   269 AGPLLLRHIPTQNKSTSQVMNILWELCLTSNIKSQTVPSYDQHHFGFWYSIAHPSVICTDDKGVF 333

  Fly   453 HCAPLSHDFYFA--FLGIAPMKADLRFLKSLAINSIRY 488
             ...||.::..|  ...:.|.:     :..|:..||.|
Mouse   334 -ATYLSQEYQLAAETFNLTPFQ-----VWDLSYESINY 365

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Adgf-B	NP_649006.2	A_deaminase_N	36..113	CDD:285627
		adm_rel	56..515	CDD:273620	75/298 (25%)
		ADGF	93..507	CDD:238646	75/298 (25%)
Adal	XP_011238139.1	ADA_AMPD	17..380	CDD:238250	75/298 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1816
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810