DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Adgf-B and AMPdeam

DIOPT Version :9

Sequence 1:	NP_649006.2	Gene:	Adgf-B / 39975	FlyBaseID:	FBgn0036751	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_001285233.1	Gene:	AMPdeam / 32352	FlyBaseID:	FBgn0052626	Length:	798	Species:	Drosophila melanogaster

Alignment Length:	383	Identity:	96/383 - (25%)
Similarity:	144/383 - (37%)	Gaps:	123/383 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   189 NVTKY-LT--------RRFSMYPFSKFIS--NNQAWAHFMGIFILLDGLLCHAPIWAEYYYNALK 242
            |:|.| ||        .|.:.:.|.||.|  |....:....:|:..|..|.     .:|:...:|
  Fly   393 NLTTYDLTVDMLDVHADRNTFHRFDKFNSKYNPIGESRLREVFLKTDNYLN-----GKYFAQIIK 452

  Fly   243 EFA----EDGVQYLELRSLL----P------PLYCIDGDMLTIRDTVAIYNSELERFRADHPD-- 291
            |.|    |...|..|||..:    |      ..:.||.|         :|:|.: |:....|.
  Fly   453 EVAFDLEESKYQNAELRLSIYGKSPDEWYKLAKWAIDND---------VYSSNI-RWLIQIPRLF 507

  Fly   292 --FIGSKL----------IYAPLRGVEPSVVEQYVKTA-----VELNKEFPNFMVGFDLVGQE-E 338
              |..:|:          |:.||          :..||     .||:: |..:::|||.|..| :
  Fly   508 DIFKSNKMMKSFQEILNNIFLPL----------FEATARPSKHPELHR-FLQYVIGFDSVDDESK 561

  Fly   339 LGRPLIDFVEPLLKMPE-----------HINFYFHAGET-----------NWF--------GSPI 373
            ...||.|...|   .||           :..:|.:|..|           |.|        ..|:
  Fly   562 PENPLFDNDVP---RPEEWTYEENPPYAYYIYYMYANMTVLNKFRQSRNMNTFVLRPHCGEAGPV 623

  Fly   374 DENLVDAILLGTKRIGHGYAITKHPMMMRLAKLLGIAIEVCPVSNQVLQLGVDYRNHPAALLLAA 438
             ::||...|: .:.|.||..:.|.|::..|..|..|.|.:.|:||..|.|  :|..:|....||.
  Fly   624 -QHLVCGFLM-AENISHGLLLRKVPVLQYLYYLTQIGIAMSPLSNNSLFL--NYHRNPLPEYLAR 684

  Fly   439 NVPIVISSDDPSFWHCA--PLSHDFYFAFLGIAPMKADLRFLKS-----LAINSIRYS 489
            .:.|.:|:|||..:|..  ||..::..|        |.:..|.|     ||.||:..|
  Fly   685 GLIISLSTDDPLQFHFTKEPLMEEYSIA--------AQVWKLSSCDMCELARNSVMMS 734

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Adgf-B	NP_649006.2	A_deaminase_N	36..113	CDD:285627
		adm_rel	56..515	CDD:273620	96/383 (25%)
		ADGF	93..507	CDD:238646	96/383 (25%)
AMPdeam	NP_001285233.1	PLN03055	248..784	CDD:178613	96/383 (25%)
AMPdeam	NP_001285233.1	AMPD	284..780	CDD:238644	96/383 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1816
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900