DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6034 and 4930438A08Rik

DIOPT Version :9

Sequence 1:	NP_649005.1	Gene:	CG6034 / 39974	FlyBaseID:	FBgn0036750	Length:	479	Species:	Drosophila melanogaster
Sequence 2:	NP_001361634.1	Gene:	4930438A08Rik / 73988	MGIID:	1921238	Length:	536	Species:	Mus musculus

Alignment Length:	535	Identity:	107/535 - (20%)
Similarity:	192/535 - (35%)	Gaps:	152/535 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 KTKETAKIVIIGAGASGVAAATKLLEQGFKNVLLFEAEDRIGGRINT--ILFANSLIDLGAQWCH 74
            :|.|..::|:||||.:|:.|| |:|:.....|.:.||..|:||||.|  :..|:..|:|||.
Mouse    57 QTAERKQVVVIGAGMAGLTAA-KILQDAGHQVTVLEASGRVGGRIETHRVPGAHWYIELGAM--- 117

  Fly    75 GEEGNVVYEKVKDLDVLDRTGDYVVHFIRSNKEILTDVHNKALTELTNAFEVPGEHEGSVGDAFN 139
                .:........:::.:.|..:..|...|.:  |.|....:.:.:.|.:.   ..|.:|.:..
Mouse   118 ----RIPINHRLSHELIKKFGLMLKEFCPCNNQ--TWVLVNGVRQRSGAVQA---DPGLLGYSVR 173

  Fly   140 AYWKENIHQLVPNDKTIAKEAQD----CLKKVICSM--DACDNLSELSYRNF--RNFAIAGGDQN 196
            |             ..:.|.|:.    .|:|::..:  .:|..:.| .|.:|  :.:.|..|  |
Mouse   174 A-------------DEVGKTAEQLFDASLRKIVEELKNSSCQEVLE-KYDSFSTKEYLIKVG--N 222

  Fly   197 LSWRQKGYWKFLSVLLNSSDN--------------------------------QPGDQGILKGHV 229
            ||   :|..:.:..:||:...                                |.....:|.|.|
Mouse   223 LS---RGAVQMIGDMLNTDSGYYEAFTETLRGIISFFQDPRFDEIVGGFDQLPQALHNSLLPGTV 284

  Fly   230 HLNKRIAKINWEGDGELTLRCWNGQF-----------VSADHVICTVSLGVLREKHHKLFVPALP 283
            .......::...||      |.:..:           ::||.|:...:....|...   |.|.|.
Mouse   285 WFYSPAEEVEMSGD------CVHVTYRTPDPLLPRARLTADFVVVATTAKAARLLR---FQPPLS 340

  Fly   284 ASKIRSIEGLKLGTVNKFYL----EFEEQPVPENI--------REMAFLWLEEDLKELRSG---- 332
            .:|..::..:...:..|..|    .|.|:   :.|        |...|::....:....:|
Mouse   341 LNKQDALRSVHYNSATKVILACTQRFWER---DGIFSGKSSTDRPSRFIYYPNHIFPNGAGVILA 402

  Fly   333 KYFWLESVCYFHRVDCQPRLLQGWIIGAHSRYVETISEEQVLEGIMWMFRKFLKFSVPYP--KNF 395
            .|...:...:|..:|             |::.|:.:.::  |..:....::.|:...||.  ||
Mouse   403 SYTLDDDSVFFTALD-------------HTQVVDIVLDD--LAALHSRAKEELRALCPYSAIKN- 451

  Fly   396 LRSQWQSNPNFRGSYSYYSTYADELRTGRTDLASPLVDVTGRPRIQFAGEASSRNHFSTVHG--- 457
                |..:|...|.:::::.|.      ..|.|..|....|  .:.||||     |....||
Mouse   452 ----WSQDPYSMGGFAFFTPYQ------YVDYAQELSQPEG--LVFFAGE-----HTDLPHGWID 499

  Fly   458 -AIESGWREAERLNE 471
             ||:||.|.|:.:.|
Mouse   500 TAIKSGLRVAKNIQE 514

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6034	NP_649005.1	Amino_oxidase	33..470	CDD:279874	96/511 (19%)
CG6034	NP_649005.1	NAD_binding_8	<35..88	CDD:290186	15/54 (28%)
4930438A08Rik	NP_001361634.1	PRK12779	<42..>98	CDD:183740	16/41 (39%)
4930438A08Rik	NP_001361634.1	Amino_oxidase	71..512	CDD:366721	99/517 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839600
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840