DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6034 and smox

DIOPT Version :9

Sequence 1:	NP_649005.1	Gene:	CG6034 / 39974	FlyBaseID:	FBgn0036750	Length:	479	Species:	Drosophila melanogaster
Sequence 2:	NP_001039135.1	Gene:	smox / 733959	XenbaseID:	XB-GENE-5840847	Length:	534	Species:	Xenopus tropicalis

Alignment Length:	522	Identity:	164/522 - (31%)
Similarity:	255/522 - (48%)	Gaps:	85/522 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 KIVIIGAGASGVAAATKLLEQGFKNVLLFEAEDRIGGRINTILFANSLIDLGAQWCHGEEGNVVY 82
            :|||||||.:|::||..|||:||.:|.:.||.||||||:.:|...::..:|||.|.||..||.:|
Frog    26 RIVIIGAGLAGLSAAKTLLEKGFTDVTILEASDRIGGRVQSIKLEHATFELGATWIHGSNGNPIY 90

  Fly    83 EKVKDLDVLDRTGD----------Y----VVHFI-----RSNKEIL---TDVHNKA--LTE--LT 121
            ...:|..:|:.|.|          |    |.|::     |..|:::   :||:|:.  ||:  ..
Frog    91 HLAEDNGLLEETTDGERSVGRISLYSKNGVAHYLTNSGHRIPKDLVEEFSDVYNEVYNLTQEFFQ 155

  Fly   122 NAFEVPGEHEGSVG----DAFNAYWKENIHQLVPNDKTIAKEAQDCLKKVICSMDACD----NLS 178
            |...|..|.:.|||    |......||:     |:|....|:.:..:.:....:::|:    ::.
Frog   156 NGKPVNAESQNSVGVFTRDVVRKRIKED-----PDDSESTKKLKLAMVQQFLKVESCESSSHSMD 215

  Fly   179 ELSYRNFRNFAIAGGDQNLSWRQKGYWKFLSVLLNSSDNQPGDQGILKGHVHLNKRIAKINW--- 240
            |:|...|..:....|..::.  ..|:.:.:.:|.:|         :.|..:.|.|.:..::|
Frog   216 EVSLSEFGEWTEIPGAHHVI--PCGFIRIVEILSSS---------VPKSLIQLRKPVKCVHWNRS 269

  Fly   241 ----------------EGDG-ELTLRCWNGQFVSADHVICTVSLGVLREKHHKLFVPALPASKIR 288
                            |..| .:.:.|.:.:|::|||||.|.||||:::.|..||.|:||..|:.
Frog   270 IRKQIDRVADHNNDQVEDKGYPVFVECEDYEFIAADHVIVTASLGVMKKFHETLFRPSLPEEKVT 334

  Fly   289 SIEGLKLGTVNKFYLEFEEQPVPENIREMAFLWLEEDLKELRSGKY---FWLESVCYFHRVDCQP 350
            :|:.|.:.|.:|.:|||||.........:.|:|  ||..|..|..|   .|.:.:|.|..:....
Frog   335 AIDKLGISTTDKIFLEFEEPFWSPECNSIQFVW--EDEAESESLTYPEELWYKKICSFDVLYPPE 397

  Fly   351 R---LLQGWIIGAHSRYVETISEEQVLEGIMWMFRKFL-KFSVPYPKNFLRSQWQSNPNFRGSYS 411
            |   :|.|||.|..:..:|...:|.|.|....:.|||. ..::|.|:..:||.|.|||.|.||||
Frog   398 RYGYVLSGWICGEEALIMEKYDDETVAETCTELLRKFTGNPNIPKPRRIMRSSWGSNPYFFGSYS 462

  Fly   412 YYSTYADELRTGRTDLASPL----VDVTGRPRIQFAGEASSRNHFSTVHGAIESGWREAERLNEF 472
            |  |...........||.||    ...|...::.|:|||:.|.::||.|||:.||.|||:||.|.
Frog   463 Y--TQVGSSGEDVEKLAKPLPYTESSKTAPLQVMFSGEATHRKYYSTTHGALLSGQREADRLAEM 525

  Fly   473 YE 474
            |:
Frog   526 YQ 527

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6034	NP_649005.1	Amino_oxidase	33..470	CDD:279874	151/501 (30%)
CG6034	NP_649005.1	NAD_binding_8	<35..88	CDD:290186	24/52 (46%)
smox	NP_001039135.1	PLN02568	23..526	CDD:215308	163/519 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D375579at33208
OrthoFinder	1	1.000	-	-		FOG0000632
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10742
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2622
SonicParanoid	1	1.000	-	-		X429
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	8.050