DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6034 and paox

DIOPT Version :9

Sequence 1:	NP_649005.1	Gene:	CG6034 / 39974	FlyBaseID:	FBgn0036750	Length:	479	Species:	Drosophila melanogaster
Sequence 2:	NP_001314981.1	Gene:	paox / 562105	ZFINID:	ZDB-GENE-090312-204	Length:	510	Species:	Danio rerio

Alignment Length:	513	Identity:	159/513 - (30%)
Similarity:	229/513 - (44%)	Gaps:	89/513 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 AKIVIIGAGASGVAAATKLLEQGFKNVLLFEAEDRIGGRINTILFANSLIDLGAQWCHG-EEGNV 80
            ::|.|||.|.||:.||.||::.||.||.:.||..|.||||.|....:::|::||.|.|| .:.|.
Zfish    12 SQIFIIGCGISGIGAAQKLIKHGFHNVRIIEATARSGGRIRTGRLGDNIIEIGANWIHGPSKENP 76

  Fly    81 VYEKVKDLDVLDRTG--------DYVVH-------FIRSNKEILTDVHNKALTELTNAFE----- 125
            |:....|..:||:..        |...|       |..|.:::..:....||.......|
Zfish    77 VFRLACDYQLLDKESMSEENQAIDIGGHPLFVPNWFTSSGRKLGPETMGPALEFFMTLLERSQQF 141

  Fly   126 --VPGEHEGSVGDAFNA--------YWKENIHQLVPNDKTIAKEAQ-DCLKKVICSMDACDNLSE 179
              ..||...|||:...|        .|||:      .|....:.|. :.|.|:.|.:.....:.:
Zfish   142 HSTGGEPLPSVGEFIKAEAERLAPEEWKED------RDNFAVRMAMINTLLKLECCVSGTHTMDD 200

  Fly   180 LSYRNFRNF-AIAGGDQNLSWRQKGYWKFLSVLLNSSDNQPGDQGILKGH---------VHLNKR 234
            :....|..: .:.|.|...                     ||....|..|         |..||.
Zfish   201 VGLGAFGMYTTLPGLDCTF---------------------PGGYEGLTDHMMKELPRDIVLYNKP 244

  Fly   235 IAKINWE---------GDG-ELTLRCWNGQFVSADHVICTVSLGVLREKHHKLFV-PALPASKIR 288
            :..|:|.         |.. .:|:.|.||:..:|||||.||.||.:: ||...|: |:.|..|:.
Zfish   245 VKCIHWNYTKNGPNTGGTSFPVTIECVNGETFAADHVIVTVPLGYMK-KHQNTFLSPSFPLHKLH 308

  Fly   289 SIEGLKLGTVNKFYLEFEEQPVPENIREMAFL-WLEE-DLKELRSG-KYFWLESVCYFHRVDCQP 350
            ||:.:..||.||.::|| |||..:...|:.:| |.:| .|.::.|. |..|:..:..|..:....
Zfish   309 SIQRMGFGTNNKIFVEF-EQPFWDEDCELIYLVWEDETHLTDVVSDLKMSWIRKLTGFTVLKPTE 372

  Fly   351 R---LLQGWIIGAHSRYVETISEEQVLEGIMWMFRKFLKFSVPYPKNFLRSQWQSNPNFRGSYSY 412
            |   :|.|||.|..|.|:|::||.:||:.:..:.|.|.......|:..|||||...|...|||||
Zfish   373 RFGHVLCGWIAGQESEYMESLSELEVLQTVTQLLRIFTGNPTIMPRKLLRSQWFHEPYSCGSYSY 437

  Fly   413 YSTYADELRTGRTDLASPLVDVTGRP-RIQFAGEASSRNHFSTVHGAIESGWREAERL 469
            .:...............||.....:| ::.|||||:.|:.|||||||:.|||||||||
Zfish   438 VAKGCSGYDIDNLAEPLPLKGSNSKPLQVLFAGEATHRSFFSTVHGALLSGWREAERL 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6034	NP_649005.1	Amino_oxidase	33..470	CDD:279874	150/497 (30%)
CG6034	NP_649005.1	NAD_binding_8	<35..88	CDD:290186	21/53 (40%)
paox	NP_001314981.1	Amino_oxidase	26..503	CDD:332356	152/499 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583673
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0685
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D375579at33208
OrthoFinder	1	1.000	-	-		FOG0000632
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_102123
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2622
SonicParanoid	1	1.000	-	-		X429
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.680