Protein Alignment CG6034 and kdm1a

DIOPT Version :10

• Sequence 1: NP_649005.1
• Gene: CG6034 / 39974
• FlyBaseID: FBgn0036750
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_001229924.1
• Gene: kdm1a / 558450
• ZFINID: ZDB-GENE-030131-7828
• Length: 833
• Species: Danio rerio
• Alignment Length: 627
• Identity: 150/627 - (23%)
• Similarity: 243/627 - (38%)
• Gaps: 228/627 - (36%)

  Fly    13 TKETAKIVIIGAGASGVAAATKLLEQGFKNVLLFEAEDRIGGRINTILFANSLIDLGAQWCHGEE 77
            ||:|.|:::||||.||:|||.:|...|. :|.:.|:.||:|||:.|....|.:.||||....|..
Zfish   249 TKKTGKVIVIGAGVSGLAAARQLQSFGM-DVTVLESRDRVGGRVATFRKGNYVADLGAMVVTGLG 312

  Fly    78 GN---VVYEKV----------------------------KDLD---------VLDRTGDYVVHFI 102
            ||   ||.::|                            |:.|         :|:.| .|:.|.:
Zfish   313 GNPMAVVSKQVNMELAKIKQKCPLYEANGQAGERCTSVPKEKDEMVEQEFNRLLEAT-SYLSHQL 376

  Fly   103 RSNKEILTDVHNKALTELTNAFEVPGE-HEGSVGDAFNAYWKENIHQLVPNDKTIAKEAQDCLKK 166
            ..|     .::||.:: |..|.||..: .|..|.|....:||:.:       || .:|.:|.|.|
Zfish   377 DFN-----FLNNKPVS-LGQALEVVIQLQEKHVKDEQIEHWKKIV-------KT-QEELKDLLNK 427

  Fly   167 VICSMDACDNLSELSYRN----------FRNFAIAGGDQNLSWRQKGYWKFLSVLLNSSD----- 216
            ::.:.:....|.: .|:.          ...|.:....::|:...|.|.:.:.:.:...:
Zfish   428 MVTTKEKVKELHQ-QYKEASEVKPPRDITAEFLVKSKHRDLTALCKEYDELVEMQVKLEERLQEL 491

  Fly   217 --NQPGDQGILKGHVHLNKRIAKI----------------------NWEGDGE-------LTLRC 250
              |.|.|       |:|:.|..:|                      :|:.|.:       ||:|
Zfish   492 EANPPSD-------VYLSSRDRQILDWHFANLEFANATPLSTLSLKHWDQDDDFEFTGSHLTVR- 548

  Fly   251 WNG-----------------------QFVSA--------------------DHVICTVSLGVLRE 272
             ||                       ::.|:                    |.|:||:.|||:::
Zfish   549 -NGYSCVPVALAEGLDIKLNTAVRQVRYTSSGCEVIAVNTRSTTQTFIYKCDAVLCTLPLGVMKQ 612

  Fly   273 KHHKL-FVPALPASKIRSIEGLKLGTVNKFYLEFEEQPVPENIREMAFLWLEEDLKELRSGKYFW 336
            :...: |||.||..|..:|:.:..|.:||..|.|:                          :.||
Zfish   613 QPPAVQFVPPLPEWKTAAIQRMGFGNLNKVVLCFD--------------------------RVFW 651

  Fly   337 LESVCYFHRVDC---------------QPRLLQGWIIGAHSRYVETISEE-------QVLEGIMW 379
            ..||..|..|..               :..:|...:.|..:..:|.||::       .:|:||
Zfish   652 DPSVNLFGHVGSTTASRGELFLFWNLYKAPILLALMAGEAAGIMENISDDVIVGRCLAILKGI-- 714

  Fly   380 MFRKFLKFSVPYPKNFLRSQWQSNPNFRGSYSY---------YSTYADELRTGRTDLASPLVDVT 435
                |...:||.||..:.|:|:::|..||||||         |...|..:..|      |.:...
Zfish   715 ----FGSSAVPQPKETVVSRWRADPWARGSYSYVAAGSSGNDYDLMAQPITPG------PAIPGA 769

  Fly   436 GR--PRIQFAGEASSRNHFSTVHGAIESGWREAERLNEFYEG 475
            .:  ||:.||||.:.||:.:|||||:.||.|||.|:.:.:.|
Zfish   770 SQPVPRLFFAGEHTIRNYPATVHGALLSGLREAGRIADQFLG 811

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6034	NP_649005.1	Amino_oxidase	33..470	CDD:396255	136/600 (23%)
kdm1a	NP_001229924.1	PLN02328	157..805	CDD:215187	148/619 (24%)
		COG1340	<375..>493	CDD:440951	24/132 (18%)