Protein Alignment CG6034 and MAOA

DIOPT Version :9

• Sequence 1: NP_649005.1
• Gene: CG6034 / 39974
• FlyBaseID: FBgn0036750
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_000231.1
• Gene: MAOA / 4128
• HGNCID: 6833
• Length: 527
• Species: Homo sapiens
• Alignment Length: 506
• Identity: 114/506 - (22%)
• Similarity: 193/506 - (38%)
• Gaps: 114/506 - (22%)

  Fly    19 IVIIGAGASGVAAATKLLEQGFKNVLLFEAEDRIGGRINTILFANSLIDLGAQWCHGEEGNVVYE 83
            :|:||.|.||::||..|.|.|. :||:.||.||:|||..||
Human    16 VVVIGGGISGLSAAKLLTEYGV-SVLVLEARDRVGGRTYTI------------------------ 55

  Fly    84 KVKDLDVLDRTGDYV----VHFIRSNKEILTDVHNKALTELTNAFEVPGE---HEGSVGDAFN-- 139
            :.:.:|.:|..|.||    ...:|.:||:..:.:...::|....: |.|:   ..|:....:|
Human    56 RNEHVDYVDVGGAYVGPTQNRILRLSKELGIETYKVNVSERLVQY-VKGKTYPFRGAFPPVWNPI 119

  Fly   140 AY------WK--ENIHQLVPN------------DKTIAKEAQDCLKKVICSMDACDNLSELSYRN 184
            ||      |:  :|:.:.:|.            ||...||..|    .||........:.|
Human   120 AYLDYNNLWRTIDNMGKEIPTDAPWEAQHADKWDKMTMKELID----KICWTKTARRFAYL---- 176

  Fly   185 FRNFAIAGGDQNLS-----WRQK---GYWKFLSVLLNSSDNQ-PGDQG--------ILKGHVHLN 232
            |.|..:......:|     |..|   |..:..||.....:.: .|..|        :|...|.||
Human   177 FVNINVTSEPHEVSALWFLWYVKQCGGTTRIFSVTNGGQERKFVGGSGQVSERIMDLLGDQVKLN 241

  Fly   233 KRIAKINWEGDGELTLRCWNGQFVSADHVICTVSLGVLREKHHKLFVPALPASKIRSIEGLKLGT 297
            ..:..::...| .:.:...|.:.....:||..:. ..|..|.|  |.|.|||.:.:.|:.|.:|.
Human   242 HPVTHVDQSSD-NIIIETLNHEHYECKYVINAIP-PTLTAKIH--FRPELPAERNQLIQRLPMGA 302

  Fly   298 VNKFYLEFEEQPVPENIREMAFLWLEED------LKELRSGKYFWLESVCYFHRVDCQPRLLQGW 356
            |.|..:.::|          || |.::|      :::..:.....|:..    :.|.....:.|:
Human   303 VIKCMMYYKE----------AF-WKKKDYCGCMIIEDEDAPISITLDDT----KPDGSLPAIMGF 352

  Fly   357 IIGAHSRYVETISEEQVLEGIMWMFRKFL-KFSVPYPKNFLRSQWQSNPNFRGSYSYYSTYADEL 420
            |:...:..:..:.:|...:.|..::.|.| .....:|.::....|.......|.|:.|.......
Human   353 ILARKADRLAKLHKEIRKKKICELYAKVLGSQEALHPVHYEEKNWCEEQYSGGCYTAYFPPGIMT 417

  Fly   421 RTGRTDLASPLVDVTGRPRIQFAGEASSRNHFSTVHGAIESGWREA-ERLN 470
            :.||. :..|:      .||.|||..::......:.||:|:|.|.| |.||
Human   418 QYGRV-IRQPV------GRIFFAGTETATKWSGYMEGAVEAGERAAREVLN 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6034	NP_649005.1	Amino_oxidase	33..470	CDD:279874	104/490 (21%)
		NAD_binding_8	<35..88	CDD:290186	14/52 (27%)
MAOA	NP_000231.1	YobN	15..460	CDD:224152	112/503 (22%)
		Interaction with membrane phospholipid headgroups. /evidence=ECO:0000305	520..522

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149521
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840