DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6034 and smox

DIOPT Version :9

Sequence 1:	NP_649005.1	Gene:	CG6034 / 39974	FlyBaseID:	FBgn0036750	Length:	479	Species:	Drosophila melanogaster
Sequence 2:	NP_001315115.1	Gene:	smox / 387290	ZFINID:	ZDB-GENE-031201-3	Length:	539	Species:	Danio rerio

Alignment Length:	525	Identity:	166/525 - (31%)
Similarity:	253/525 - (48%)	Gaps:	90/525 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 KIVIIGAGASGVAAATKLLEQGFKNVLLFEAEDRIGGRINTILFANSLIDLGAQWCHGEEGNVVY 82
            :||:||||.:|:||...|||.||.||.:.||.||||||:.:|....:.::|||.|.||..||.||
Zfish    26 RIVVIGAGLAGLAATKTLLENGFTNVTVLEASDRIGGRVQSIQHGKTTLELGATWIHGANGNPVY 90

  Fly    83 EKVKDLDVLDRTGDY--------------VVHFIRSN-----KEIL---TDVHNKALTELTNAF- 124
            ...:|..:|:.|.:.              |.|:..:|     |:::   :|::|: :.|||..|
Zfish    91 HLAEDNGLLEHTTEEERSVGRISLYAKNGVAHYQTNNGKRIPKDLVEEFSDLYNE-VYELTQEFF 154

  Fly   125 ----EVPGEHEGSVGDAFNAYWKENIHQLVPNDKTIAKEAQDCLKKVICSMDACD----NLSELS 181
                .|..|.:.|||.......::.| .|.|.|....::.:..:.:....:::|:    |:.|:|
Zfish   155 QNGKPVGAESQNSVGIFTRDVVRKKI-MLDPYDSESIRKLKLSMLQQYLKVESCESSSPNMDEVS 218

  Fly   182 YRNFRNFAIAGGDQNLSWRQKGYWKFLSVLLNSSDNQPGDQGILKGHVHLNKRIAKINWE----- 241
            ...|..:....|..::.  ..|:.|.:.:|.         |.|....:||:|.:.:::|.
Zfish   219 LSEFGEWTEIPGAHHVI--PTGFIKVVEILA---------QDIPSCVLHLSKPVRRVHWNCSSQD 272

  Fly   242 ----GD------------GELTLRCWNGQFVSADHVICTVSLGVLREKHHKLFVPALPASKIRSI 290
                ||            ..:.:.|.:|:.:.|||||.|.|||||::.|..||.|.||..|.::|
Zfish   273 AEEFGDQVDHNQDQRPSPSPVCVECEDGERLLADHVILTASLGVLKKAHKTLFSPGLPQDKAQAI 337

  Fly   291 EGLKLGTVNKFYLEFEEQPVPENIREMAFLWLEEDLKELRSGKY---FWLESVCYF---HRVDCQ 349
            :.|.:.|.:|.:|||.|.........:.|:|  ||..:|.|..|   .|...:|.|   :..:..
Zfish   338 QKLGISTTDKIFLEFAEPFWSPECNSIQFVW--EDEAQLESQAYPEELWYRKICSFDVLYPPERY 400

  Fly   350 PRLLQGWIIGAHSRYVETISEEQVLEGIMWMFRKFL-KFSVPYPKNFLRSQWQSNPNFRGSYSYY 413
            ..:|.|||.|..:..:|...:|.|.|....:.|:|. ..::|.|:..|||.|.|||..|||||:
Zfish   401 GHMLSGWICGEEALRMERCDDETVAEICTELLRQFTGNQNIPKPRRILRSSWGSNPYIRGSYSF- 464

  Fly   414 STYADELRTGRT-----DLASPL--VDVTGRPRIQ--FAGEASSRNHFSTVHGAIESGWREAERL 469
                  .|.|.:     .||.||  :..|..|.:|  |||||:.|.::||.|||:.||.|||.||
Zfish   465 ------TRVGSSGRDVEKLAEPLPYIKNTKAPPLQVLFAGEATHRKYYSTTHGALLSGQREANRL 523

  Fly   470 NEFYE 474
            .|.|:
Zfish   524 MELYQ 528

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6034	NP_649005.1	Amino_oxidase	33..470	CDD:279874	154/504 (31%)
CG6034	NP_649005.1	NAD_binding_8	<35..88	CDD:290186	26/52 (50%)
smox	NP_001315115.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583685
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0685
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D375579at33208
OrthoFinder	1	1.000	-	-		FOG0000632
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_102123
Panther	1	1.100	-	-	O	PTHR10742
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2622
SonicParanoid	1	1.000	-	-		X429
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	11	10.780