DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6034 and Paox

DIOPT Version :9

Sequence 1:	NP_649005.1	Gene:	CG6034 / 39974	FlyBaseID:	FBgn0036750	Length:	479	Species:	Drosophila melanogaster
Sequence 2:	NP_001099781.1	Gene:	Paox / 293589	RGDID:	1561125	Length:	531	Species:	Rattus norvegicus

Alignment Length:	467	Identity:	139/467 - (29%)
Similarity:	215/467 - (46%)	Gaps:	75/467 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 NSLIDLGAQWCHG-EEGNVVYEKVKDLDVLD-----------RTGDYVVHFIRSNKEILTDVHNK 115
            :.:::|||.|.|| .:||.|::...:..:|.           .||.:|.....|.....|.|..:
  Rat    81 SGVVELGAHWIHGPSQGNPVFQLAAEFGLLGEKELSEENQLVETGGHVALPSVSCTSSGTSVSLE 145

  Fly   116 ALTELTNAF--------EVPGEHE---GSVGDAFNAYWKENIHQLV------PNDKTIAKEAQDC 163
            .:||:.:.|        |...|.|   .|||:    :.|:.|.|.|      .|.|.:.....:.
  Rat   146 LVTEMGSLFYGLIDRTREFLNESETPMASVGE----FLKKEISQQVANWTEDENTKRLKLAVLNT 206

  Fly   164 LKKVICSMDACDNLSELSYRNFRNFAIAGG-DQNLSWRQKGYWKFLSVLLNSSDNQPGDQGILKG 227
            ...:.|.:....::..::...|..:.:..| |..||   .||....:.:|.|         :.|.
  Rat   207 FFNIECCVSGTHSMDLVALAPFGEYTVLPGLDCTLS---GGYQGLTNCILAS---------LPKE 259

  Fly   228 HVHLNKRIAKINWEGD-------GE---LTLRCWNGQFVSADHVICTVSLGVLREKHHKLFVPAL 282
            .:..:|.:..|:|.|.       ||   :.:.|.:|..:.|.|||.||.||.|:|.....|.|.|
  Rat   260 VMVFDKPVKTIHWNGSFQEAAFPGETFPVLVECEDGARLPAHHVIVTVPLGFLKEHQDTFFEPPL 324

  Fly   283 PASKIRSIEGLKLGTVNKFYLEFEEQPVPENIREMAFLWLEEDLKELR----SGKYFWLESVCYF 343
            ||.|..:|..|..||.||.:|||||.....:.:.:..:|  ||...|:    |.:..|.:.:..|
  Rat   325 PAKKAEAIRKLGFGTNNKIFLEFEEPFWEPDCQFIQVVW--EDTSPLQDSPLSLQDTWFKKLIGF 387

  Fly   344 HRVDC--QPRLLQGWIIGAHSRYVETISEEQVLEGIMWMFRKFL-KFSVPYPKNFLRSQWQSNPN 405
            ..:..  ...:|..:|.|..|.::||:|:|:||..:..:.|:.. ...:|..|:.|||:|.|.|.
  Rat   388 LVLPSFESSHVLCAFIAGLQSEFMETLSDEEVLLSLTQVLRRVTGNPQLPAAKSVLRSRWHSAPY 452

  Fly   406 FRGSYSYYS--TYADELRTGRTDL-ASPL-VDVTG-RPRIQFAGEASSRNHFSTVHGAIESGWRE 465
            .||||||.:  :..|:|     || |.|| .|.|| :.::.|||||:.|..:||.|||:.|||||
  Rat   453 TRGSYSYVAVGSTGDDL-----DLMAQPLPADGTGTQLQVLFAGEATHRTFYSTTHGALLSGWRE 512

  Fly   466 AERLNEFYEGRA 477
            |:||...::.:|
  Rat   513 ADRLIGLWDSQA 524

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6034	NP_649005.1	Amino_oxidase	33..470	CDD:279874	137/458 (30%)
CG6034	NP_649005.1	NAD_binding_8	<35..88	CDD:290186	9/25 (36%)
Paox	NP_001099781.1	Amino_oxidase	77..517	CDD:279874	137/458 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343421
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0685
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D375579at33208
OrthoFinder	1	1.000	-	-		FOG0000632
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_102123
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X429
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.650