Protein Alignment CG7460 and Kdm1a

DIOPT Version :10

• Sequence 1: NP_649004.1
• Gene: CG7460 / 39973
• FlyBaseID: FBgn0036749
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: XP_006539392.1
• Gene: Kdm1a / 99982
• MGIID: 1196256
• Length: 877
• Species: Mus musculus
• Alignment Length: 596
• Identity: 153/596 - (25%)
• Similarity: 241/596 - (40%)
• Gaps: 175/596 - (29%)

  Fly    13 RQTARIVIVGAGSAGIAAATRLLDLGFRNVLLLEAEDRIGGRVHTIPFADNVVDLGAQWCHGEKG 77
            ::|.:::|:|:|.:|:|||.:|...|. :|.||||.||:||||.|....:.|.||||....|..|
Mouse   297 KKTGKVIIIGSGVSGLAAARQLQSFGM-DVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLGG 360

  Fly    78 N--VVYDKVKDLNLLEVTE--PHYE------TFRCVRSNKEVL---------------------- 110
            |  .|..|..::.|.::.:  |.||      |.:..:...|::
Mouse   361 NPMAVVSKQVNMELAKIKQKCPLYEANGQADTVKVPKEKDEMVEQEFNRLLEATSYLSHQLDFNV 425

  Fly   111 ----PDDLADQLKTIADMS---IPDRQAE--------LLDFEGSLGDYINMK--------YWKEL 152
                |..|...|:.:..:.   :.|.|.|        ..:.:..|...:|:|        .:||.
Mouse   426 LNNKPVSLGQALEVVIQLQEKHVKDEQIEHWKKIVKTQEELKELLNKMVNLKEKIKELHQQYKEA 490

  Fly   153 AKLPPIDRTIAEEFL-EVFHK-FEASVEAADHLFEVSGKGHLEYWLCEGEL-------------- 201
            :::.| .|.|..||| :..|: ..|..:..|.|.|..||  ||..|.|.|.
Mouse   491 SEVKP-PRDITAEFLVKSKHRDLTALCKEYDELAETQGK--LEEKLQELEANPPSDVYLSSRDRQ 552

  Fly   202 LLNWKDKGYKRF-----LKLLMKAPEDQSEDLGILKDH-------------------VRLNRRIA 242
            :|:|.....: |     |..|.....||.:|......|                   ::||..:.
Mouse   553 ILDWHFANLE-FANATPLSTLSLKHWDQDDDFEFTGSHLTVRNGYSCVPVALAEGLDIKLNTAVR 616

  Fly   243 EINW--KGADELTVRCWNGE---VITADHVICTVSLGVLKEQHPKL-FVPALPAAKVRAIEGLKL 301
            ::.:  .|.:.:.|...:..   :...|.|:||:.|||||:|.|.: |||.||..|..|::.:..
Mouse   617 QVRYTASGCEVIAVNTRSTSQTFIYKCDAVLCTLPLGVLKQQPPAVQFVPPLPEWKTSAVQRMGF 681

  Fly   302 GTVDKFFLEFENPPLPGDWPGFNCLWLKEDLEELRASELFWLESV--FG--------------FY 350
            |.::|..|.|:                          .:||..||  ||              |:
Mouse   682 GNLNKVVLCFD--------------------------RVFWDPSVNLFGHVGSTTASRGELFLFW 720

  Fly   351 PVSRQPRILQGWIIGPHARHMETLTEE-------RVLEGLLWLFRKFLPFETAHPVRMLRTQWHA 408
            .:.:.| ||...:.|..|..||.::::       .:|:|:      |.......|...:.::|.|
Mouse   721 NLYKAP-ILLALVAGEAAGIMENISDDVIVGRCLAILKGI------FGSSAVPQPKETVVSRWRA 778

  Fly   409 NPNFRGSYTFRSTYTDALRTG-AWDLEA----PLQDVCGR----PRLQFAGESTHKHFYSTVHGA 464
            :|..||||    :|..|..:| .:||.|    |...:.|.    |||.||||.|.:::.:|||||
Mouse   779 DPWARGSY----SYVAAGSSGNDYDLMAQPITPGPSIPGAPQPIPRLFFAGEHTIRNYPATVHGA 839

  Fly   465 VETGWREAERL 475
            :.:|.|||.|:
Mouse   840 LLSGLREAGRI 850

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7460	NP_649004.1	Amino_oxidase	32..476	CDD:396255	145/577 (25%)
Kdm1a	XP_006539392.1	PHA03378	<39..>99	CDD:223065
		PLN02328	204..850	CDD:215187	152/594 (26%)