DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7460 and smox

DIOPT Version :9

Sequence 1:	NP_001261998.1	Gene:	CG7460 / 39973	FlyBaseID:	FBgn0036749	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	NP_001039135.1	Gene:	smox / 733959	XenbaseID:	XB-GENE-5840847	Length:	534	Species:	Xenopus tropicalis

Alignment Length:	545	Identity:	169/545 - (31%)
Similarity:	250/545 - (45%)	Gaps:	124/545 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 RIVIVGAGSAGIAAATRLLDLGFRNVLLLEAEDRIGGRVHTIPFADNVVDLGAQWCHGEKGNVVY 81
            ||||:|||.||::||..||:.||.:|.:|||.|||||||.:|.......:|||.|.||..||.:|
Frog    26 RIVIIGAGLAGLSAAKTLLEKGFTDVTILEASDRIGGRVQSIKLEHATFELGATWIHGSNGNPIY 90

  Fly    82 DKVKDLNLLEVTE-----------------PHYETFRCVRSNKEVLPD--DLADQLKTIADMSIP 127
            ...:|..|||.|.                 .||.|....|..|:::.:  |:.:::..:......
Frog    91 HLAEDNGLLEETTDGERSVGRISLYSKNGVAHYLTNSGHRIPKDLVEEFSDVYNEVYNLTQEFFQ 155

  Fly   128 DRQAELLDFEGSLGDYINMKYWKELAKLP-------PIDRTIAEEFLEVFHKFEASVEAADH-LF 184
            :.:....:.:.|:|.:......|.:.:.|       .:...:.::||:|     .|.|::.| :.
Frog   156 NGKPVNAESQNSVGVFTRDVVRKRIKEDPDDSESTKKLKLAMVQQFLKV-----ESCESSSHSMD 215

  Fly   185 EVSGKGHLEYWLCE-GELLLNWKD---------KGYKRFLKLLMKAPEDQSEDLGILKDHVRLNR 239
            |||        |.| ||    |.:         .|:.|.:::|..:         :.|..::|.:
Frog   216 EVS--------LSEFGE----WTEIPGAHHVIPCGFIRIVEILSSS---------VPKSLIQLRK 259

  Fly   240 RIAEINW-----KGADELT---------------VRCWNGEVITADHVICTVSLGVLKEQHPKLF 284
            .:..::|     |..|.:.               |.|.:.|.|.|||||.|.||||:|:.|..||
Frog   260 PVKCVHWNRSIRKQIDRVADHNNDQVEDKGYPVFVECEDYEFIAADHVIVTASLGVMKKFHETLF 324

  Fly   285 VPALPAAKVRAIEGLKLGTVDKFFLEFENPPLPGDWPGFNCLWLKE-DLEELRASELFWLESVFG 348
            .|:||..||.||:.|.:.|.||.|||||.|....:......:|..| :.|.|...|..|.:.:..
Frog   325 RPSLPEEKVTAIDKLGISTTDKIFLEFEEPFWSPECNSIQFVWEDEAESESLTYPEELWYKKICS 389

  Fly   349 F---YPVSRQPRILQGWIIGPHARHMETLTEERVLEGLLWLFRKF-----LPFETAHPVRMLRTQ 405
            |   ||..|...:|.|||.|..|..||...:|.|.|....|.|||     :|    .|.|::|:.
Frog   390 FDVLYPPERYGYVLSGWICGEEALIMEKYDDETVAETCTELLRKFTGNPNIP----KPRRIMRSS 450

  Fly   406 WHANPNFRGSYTFRST---------------YTDALRTGAWDLEAPLQDVCGRPRLQFAGESTHK 455
            |.:||.|.|||::...               ||::.:|      ||||       :.|:||:||:
Frog   451 WGSNPYFFGSYSYTQVGSSGEDVEKLAKPLPYTESSKT------APLQ-------VMFSGEATHR 502

  Fly   456 HFYSTVHGAVETGWREAERLHLYYR 480
            .:|||.|||:.:|.|||:||...|:
Frog   503 KYYSTTHGALLSGQREADRLAEMYQ 527

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7460	NP_001261998.1	Amino_oxidase	32..476	CDD:279874	156/524 (30%)
CG7460	NP_001261998.1	NAD_binding_8	33..>74	CDD:290186	20/40 (50%)
smox	NP_001039135.1	PLN02568	23..526	CDD:215308	168/542 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D375579at33208
OrthoFinder	1	1.000	-	-		FOG0000632
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR10742
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X429
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	7.020