DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7460 and paox1

DIOPT Version :9

Sequence 1:	NP_001261998.1	Gene:	CG7460 / 39973	FlyBaseID:	FBgn0036749	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	NP_001107075.1	Gene:	paox1 / 564675	ZFINID:	ZDB-GENE-081104-436	Length:	490	Species:	Danio rerio

Alignment Length:	520	Identity:	157/520 - (30%)
Similarity:	239/520 - (45%)	Gaps:	97/520 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 IVIVGAGSAGIAAATRLLDLGFRNVLLLEAEDRIGGRVHTIPFADNVVDLGAQWCHG--EKGNVV 80
            ||:||||.||:|||.:|.:.||.:|.:|||.:.:||||.|....:..||.|||:.||  || |.|
Zfish     8 IVVVGAGVAGLAAAKKLKEYGFNDVTVLEAAENVGGRVATATLGNACVDTGAQYIHGTSEK-NPV 71

  Fly    81 YDKVKDLNLLEVTEPHYETFRCVRSNKEVLPDDLADQLKTIADMSIPDRQAELLDFEGSLGDYIN 145
            |..:|.| |.::.|...|.|...:.:|  :..:.|.:.....:..|..|.:.  :...|||::..
Zfish    72 YCLLKGL-LNQLPEMGEEAFYNNKGHK--VNANFARRAYEHGESFIYHRGSG--NSGKSLGEHYA 131

  Fly   146 MK--------YWKELAKLPPIDRTIAEEFLEVFHKFEASVEAADHLFEVSGKGHLEYWLCEGELL 202
            :|        ...|.|::..:...:.::.|       ..:.|:| |..:|    |:.|    :..
Zfish   132 VKTQGVIERLQEDEKARMQSVFALVGKDML-------IDIGASD-LHRIS----LDSW----QYY 180

  Fly   203 LNWKDK----GYKRFLKLLMKAPEDQSEDLGILKDHVRLNRRIAEINWKG---------ADELTV 254
            ::..|.    |:...|..|:|      ||..  ||.:.|.|.:..|.|.|         :.|..|
Zfish   181 IDMGDSVNITGFMYQLVDLLK------EDFP--KDRLLLKREVRTIKWDGSFPSPQNEASPEGKV 237

  Fly   255 R-------CWNGEVITADHVICTVSLGVLKEQHPKLFVPALPAAKVRAIEGLKLGTVDKFFLEFE 312
            |       |.:||.|.|||||.|||||.||.|...||:|:||..|:..|..|..|.:.|.||.:|
Zfish   238 RQYPVCIVCEDGEEILADHVIVTVSLGCLKAQASDLFIPSLPTEKIEVINKLCFGNIAKIFLAYE 302

  Fly   313 NPPLPGDWPGFNCLWLKEDLEELRASELFWLESVFGF---YPVSRQPRILQGWIIGPHARHMETL 374
            ......|....:.::..:....:..:::.||:|:..|   .|..|...:|.||..|..|..:||:
Zfish   303 EAFWENDVGSISFIYEDDTPASISTNKMQWLKSMQSFSVLRPKERFGNVLIGWCPGEIADLVETM 367

  Fly   375 TEERVLEGLLWLFRKF------LPFETAHPVRMLRTQWHANPNFRGSYTFRSTYTDALRTGAWDL 433
            |:..:...:....:.|      :|    .|..:|.|:|.:|...:|||||       |..|   :
Zfish   368 TDNELSAAVTDHLKMFFGPSANIP----QPKSILCTKWRSNKFIKGSYTF-------LPVG---V 418

  Fly   434 EAPLQDVCGRP-----------RLQFAGESTHKHFYSTVHGAVETGWREAERLHLYYR---ARTS 484
            :..:.|...:|           ::.||||:|.|..|.||.||:.:|.|||:||..:|:   |.||
Zfish   419 DGQVMDTLAQPLEGSQFPDAHLQVMFAGEATMKTLYGTVQGALLSGHREADRLAAHYKDAVASTS 483

Fly 485 484
Zfish 484 483

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7460	NP_001261998.1	Amino_oxidase	32..476	CDD:279874	141/493 (29%)
CG7460	NP_001261998.1	NAD_binding_8	33..>74	CDD:290186	17/40 (43%)
paox1	NP_001107075.1	Amino_oxidase	22..471	CDD:279874	140/492 (28%)
paox1	NP_001107075.1	NAD_binding_8	<24..78	CDD:290186	25/54 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583682
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D375579at33208
OrthoFinder	1	1.000	-	-		FOG0000632
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10742
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X429
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.950