DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7460 and si:ch211-127i16.2

DIOPT Version :9

Sequence 1:	NP_001261998.1	Gene:	CG7460 / 39973	FlyBaseID:	FBgn0036749	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	XP_021327915.1	Gene:	si:ch211-127i16.2 / 558050	ZFINID:	ZDB-GENE-091204-54	Length:	523	Species:	Danio rerio

Alignment Length:	524	Identity:	129/524 - (24%)
Similarity:	197/524 - (37%)	Gaps:	145/524 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 IVIVGAGSAGIAAATRLLDLGFR-NVLLLEAEDRIGGRV--HTIPFADNVV--DLGAQWCHGEKG 77
            :|:||||.:|::||.||.....| :||:|||.||:|||.  ..:|.|:.|.  |:|.||....:.
Zfish     8 VVVVGAGLSGLSAARRLQKRNPRLSVLVLEARDRVGGRTVSEDLPAANGVEQWDMGGQWVSSSQI 72

  Fly    78 NVVYDKVKD------------------------LNLLEVTEPHYETFRCVRSNKEVLPDDL---- 114
            :|: :.:|:                        :.:...|.|.:...        |:.|.:
Zfish    73 HVM-ELIKEFGVEVFTQYTEGKKVHHIGGPNAKIKMYNTTVPQFSPL--------VMLDFIQVMW 128

  Fly   115 -ADQL-KTIA---DMSIPDRQAELLDFEGSLGDYINMKYW-----KELAKLPPID---RTIAEEF 166
             .|:| |||:   .||.|:  |||.| ..:|..::....|     :|||....|.   .|....|
Zfish   129 KVDKLTKTISVEDPMSSPN--AELYD-SMTLYTFMEQNIWTKDIKEELAVCSRIVFGLETSQISF 190

  Fly   167 LEVFHKFEASVEAADHLFEVS-GKGHLEYWLCEGELLLNWKDKGYKRFLKLLMKAPEDQSEDLGI 230
            | .|..:.|:......|.|.| |.|  :.:..:|         |.::..|:|:       |.:|
Zfish   191 L-FFLLYSAAAGGTLRLLETSPGSG--QEFRVKG---------GTQQLSKMLV-------EQIG- 235

  Fly   231 LKDHVRLNRRIAEINWKGADELTVRCWNGEVITADHVICTVSLGVLKEQHPK------LFVPALP 289
             .|.|||...:..|           |.:.|.|.......|||...:....|.      .:.|.||
Zfish   236 -SDRVRLGAAVTAI-----------CQDSENIKVTTSAGTVSCKAVIVACPSHLAAQIHYEPPLP 288

  Fly   290 AAKVRAIEGLKLGTVDKFFLEFENPPLPGDWPGFNCLWLKEDLE---ELRASELFWLESVFGFYP 351
            :.:.|.|:.|.:|.:.||.:.:.           ...|.::...   .:|.||...|...|....
Zfish   289 SERQRLIQSLPMGHMTKFIITYP-----------TAFWREKGFSGEIVVRPSESCPLSVTFDATS 342

  Fly   352 VSRQPRILQGWIIGPHARHM--ETLTEER--VLEGLLWLFRKFLPFETAHPVRMLRTQW------ 406
            ....|.:: |:|.|..||..  :.|.|.|  |:..|:    |:|..|.:..:......|
Zfish   343 PKGNPALV-GFITGIQARDWCDKKLEERRDAVISSLV----KYLGPEASTYIHYAEKDWGKEQYS 402

  Fly   407 ---HANPNFRGSYTFRSTYTDALRTGAWDLEAPLQDVCGRPRLQFAGESTHKHFYSTVHGAVETG 468
               ..|....|..||   |..:||           ..||  |:.:||..|...:...:.|||:.|
Zfish   403 GGCPVNVMTPGMLTF---YHPSLR-----------KPCG--RIHWAGTETATIWCGYLDGAVQAG 451

  Fly   469 WREA 472
            .|.|
Zfish   452 QRAA 455

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7460	NP_001261998.1	Amino_oxidase	32..476	CDD:279874	121/510 (24%)
CG7460	NP_001261998.1	NAD_binding_8	33..>74	CDD:290186	20/45 (44%)
si:ch211-127i16.2	XP_021327915.1	Amino_oxidase	15..459	CDD:307636	124/517 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583707
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840