Protein Alignment CG7460 and SMOX

DIOPT Version :9

• Sequence 1: NP_001261998.1
• Gene: CG7460 / 39973
• FlyBaseID: FBgn0036749
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: NP_001257620.1
• Gene: SMOX / 54498
• HGNCID: 15862
• Length: 585
• Species: Homo sapiens
• Alignment Length: 591
• Identity: 172/591 - (29%)
• Similarity: 247/591 - (41%)
• Gaps: 153/591 - (25%)

  Fly    11 KTRQTARIVIVGAGSAGIAAATRLLDLGFRNVLLLEAEDRIGGRVHTIPFADNVVDLGAQWCHGE 75
            :.|...|:|::|||.||:|||..||:.||.:|.:|||...|||||.::.......:|||.|.||.
Human    20 RRRGQPRVVVIGAGLAGLAAAKALLEQGFTDVTVLEASSHIGGRVQSVKLGHATFELGATWIHGS 84

  Fly    76 KGNVVYDKVKDLNLLEVTEPH-----------------YETFRCVRSNKEVLPD--DLADQLKTI 121
            .||.:|...:...|||.|...                 |.|....|..|:|:.:  ||.:::..:
Human    85 HGNPIYHLAEANGLLEETTDGERSVGRISLYSKNGVACYLTNHGRRIPKDVVEEFSDLYNEVYNL 149

  Fly   122 ADMSIPDRQAELLDFEGSLGDYINMKYWKELAKLPP-------IDRTIAEEFLEV------FHKF 173
            ........:....:.:.|:|.:...:....:...|.       :...:.:::|:|      .|..
Human   150 TQEFFRHDKPVNAESQNSVGVFTREEVRNRIRNDPDDPEATKRLKLAMIQQYLKVESCESSSHSM 214

  Fly   174 -EASVEAADHLFEVSGKGHLEYWLCEGELLLNWKDKGYKRFLKLLMKAPEDQSEDLGILKDHVRL 237
             |.|:.|.....|:.|..|:             ...|:.|.::||.:         ||....::|
Human   215 DEVSLSAFGEWTEIPGAHHI-------------IPSGFMRVVELLAE---------GIPAHVIQL 257

  Fly   238 NRRIAEINW----------------------------KGADE-------------LTVRCWNGEV 261
            .:.:..|:|                            :|.:|             :.|.|.:.|:
Human   258 GKPVRCIHWDQASARPRGPEIEPRGEGDHNHDTGEGGQGGEEPRGGRWDEDEQWSVVVECEDCEL 322

  Fly   262 ITADHVICTVSLGVLKEQHPKLFVPALPAAKVRAIEGLKLGTVDKFFLEFENPPLPGDW-PGFNC 325
            |.|||||.||||||||.|:...|.|.||..||.||..|.:||.||.|||||.|    .| |..|.
Human   323 IPADHVIVTVSLGVLKRQYTSFFRPGLPTEKVAAIHRLGIGTTDKIFLEFEEP----FWGPECNS 383

  Fly   326 L---WLKEDLEE---LRASELFWLESVFGF---YPVSRQPRILQGWIIGPHARHMETLTEERVLE 381
            |   |  ||..|   |......|...:.||   ||..|...:|.|||.|..|..||...:|.|.|
Human   384 LQFVW--EDEAESHTLTYPPELWYRKICGFDVLYPPERYGHVLSGWICGEEALVMEKCDDEAVAE 446

  Fly   382 GLLWLFRKF-----LPFETAHPVRMLRTQWHANPNFRGSYTFRST---------------YTDAL 426
            ....:.|:|     :|    .|.|:||:.|.:||.|||||::...               ||::.
Human   447 ICTEMLRQFTGNPNIP----KPRRILRSAWGSNPYFRGSYSYTQVGSSGADVEKLAKPLPYTESS 507

  Fly   427 RTGAWDL--------------EAPLQDVCG--RP-RLQFAGESTHKHFYSTVHGAVETGWREAER 474
            :|.....              |.||....|  :| ::.|:||:||:.:|||.|||:.:|.|||.|
Human   508 KTAHGSSTKQQPGHLFSSKCPEQPLDANRGAVKPMQVLFSGEATHRKYYSTTHGALLSGQREAAR 572

  Fly   475 LHLYYR 480
            |...||
Human   573 LIEMYR 578

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7460	NP_001261998.1	Amino_oxidase	32..476	CDD:279874	158/564 (28%)
		NAD_binding_8	33..>74	CDD:290186	17/40 (43%)
SMOX	NP_001257620.1	NAD_binding_8	<45..88	CDD:290186	18/42 (43%)
		PLN02568	50..578	CDD:215308	155/559 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149543
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0685
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D375579at33208
OrthoFinder	1	1.000	-	-		FOG0000632
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR10742
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X429
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.850