Protein Alignment CG7460 and IL4I1

DIOPT Version :9

• Sequence 1: NP_001261998.1
• Gene: CG7460 / 39973
• FlyBaseID: FBgn0036749
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: NP_001244946.1
• Gene: IL4I1 / 259307
• HGNCID: 19094
• Length: 589
• Species: Homo sapiens
• Alignment Length: 534
• Identity: 132/534 - (24%)
• Similarity: 199/534 - (37%)
• Gaps: 139/534 - (26%)

  Fly     9 LSKTRQTARIVIVGAGSAGIAAATRLLDLGFRNVLLLEAEDRIGGRVHTIPFADN----VVDLGA 69
            |::|.:..|:::||||.||:.||..|.|.|.: |.:|||::|||||:.|  :.|.    :.:|||
Human    75 LNRTLKPQRVIVVGAGVAGLVAAKVLSDAGHK-VTILEADNRIGGRIFT--YRDQNTGWIGELGA 136

  Fly    70 -----------QWCHGEKGNVVYDKVKDLNLLEVTEPHYETFRCVRSNK------EVLPDDLADQ 117
                       :.|.|          ..|||.:.|:....|:..|...|      |.:|:.|...
Human   137 MRMPSSHRILHKLCQG----------LGLNLTKFTQYDKNTWTEVHEVKLRNYVVEKVPEKLGYA 191

  Fly   118 LK---------TIADMSIPDRQAELLDFEGSLGDYINMKYWKELAKLPPIDRTIAEEFLEVFHKF 173
            |:         .|..|::  .|| |.|.: :||....||.::.        .|:.|..|...:..
Human   192 LRPQEKGHSPEDIYQMAL--NQA-LKDLK-ALGCRKAMKKFER--------HTLLEYLLGEGNLS 244

  Fly   174 EASVE------AADHLFEVSGKGHLEYWLCEGELLLNWKDKGYKRFL---KLLMKAPEDQSEDLG 229
            ..:|:      :.|..|.:|....|....|..:.|      .|.|.:   .||.:|.      |.
Human   245 RPAVQLLGDVMSEDGFFYLSFAEALRAHSCLSDRL------QYSRIVGGWDLLPRAL------LS 297

  Fly   230 ILKDHVRLNRRIAEINWKGADELTVR------CWNGEVITADHVICTVSLGVLKEQHPKLFVPAL 288
            .|...|.||..:..:. :|..::.|:      ..|.:|:.||.|:.|.|...:|.   ..|.|.|
Human   298 SLSGLVLLNAPVVAMT-QGPHDVHVQIETSPPARNLKVLKADVVLLTASGPAVKR---ITFSPPL 358

  Fly   289 PAAKVRAIEGLKLGTVDKFFLEFENPPLPGDWPGFNCLWLKEDLE-----ELRASELFWLESVFG 348
            |.....|:..|......|.||.|..|           .|.:|.:|     ..|.|.:.
Human   359 PRHMQEALRRLHYVPATKVFLSFRRP-----------FWREEHIEGGHSNTDRPSRMI------- 405

  Fly   349 FYPVSRQPRILQG---WIIGPHARHMETLTEERVLEGLLWLFRKFLPFETAHPVRMLRTQWHANP 410
            |||..|:..:|..   |  ...|.....|:.|..|       |..|....|....::|..|.
Human   406 FYPPPREGALLLASYTW--SDAAAAFAGLSREEAL-------RLALDDVAALHGPVVRQLWD--- 458

  Fly   411 NFRGSYTFRSTYTDALRTGAWDLEAPL-----QDVCGRP--RLQFAGESTHKHFYSTVHGAVETG 468
               |:...:....|....|.:.::.|.     :|....|  |:.||||.|     :..||.|||.
Human   459 ---GTGVVKRWAEDQHSQGGFVVQPPALWQTEKDDWTVPYGRIYFAGEHT-----AYPHGWVETA 515

  Fly   469 WREAERLHLYYRAR 482
            .:.|.|..:...:|
Human   516 VKSALRAAIKINSR 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7460	NP_001261998.1	Amino_oxidase	32..476	CDD:279874	120/503 (24%)
		NAD_binding_8	33..>74	CDD:290186	18/55 (33%)
IL4I1	NP_001244946.1	NAD_binding_8	86..143	CDD:290186	25/59 (42%)
		Amino_oxidase	91..523	CDD:279874	124/510 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149553
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840