Protein Alignment CG7460 and PAOX

DIOPT Version :10

• Sequence 1: NP_649004.1
• Gene: CG7460 / 39973
• FlyBaseID: FBgn0036749
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: NP_690875.1
• Gene: PAOX / 196743
• HGNCID: 20837
• Length: 511
• Species: Homo sapiens
• Alignment Length: 504
• Identity: 160/504 - (31%)
• Similarity: 233/504 - (46%)
• Gaps: 67/504 - (13%)

  Fly    17 RIVIVGAGSAGIAAATRLL-DLGFRNVLLLEAEDRIGGRVHTIPFADNVVDLGAQWCHG-EKGNV 79
            |:::||.|.||:.||.||. ...|.::.:|||..|.|||:.:......||::||.|.|| .:||.
Human    15 RVLVVGGGIAGLGAAQRLCGHSAFPHLRVLEATARAGGRIRSERCFGGVVEVGAHWIHGPSRGNP 79

  Fly    80 VYDKVKDLNLLEVTEPHYETFRCVRSNKEV-LP------DDLADQLKTIADMS-----IPDRQAE 132
            |:....:..||...|...|. :.|.:...| ||      ...:..|:.:|:|:     :.|:..|
Human    80 VFQLAAEYGLLGEKELSQEN-QLVETGGHVGLPSVSYASSGASVSLQLVAEMATLFYGLIDQTRE 143

  Fly   133 LLDFE----GSLGDYINMKYWKELAKLPPIDRT--IAEEFLEVFHKFEASVEAADHLFEVSGKGH 191
            .|...    .|:|:|:..:..:.:|.....:.|  :....|..|...|..|.....:..|:....
Human   144 FLHAAETPVPSVGEYLKKEIGQHVAGWTEDEETRKLKLAVLNSFFNLECCVSGTHSMDLVALAPF 208

  Fly   192 LEYWLCEGELLLNWKDKGYKRFLKLLMKA-PEDQSEDLGILKDHVRLNRRIAEINWKGADE---- 251
            .||.:..|  |.....|||:.....:|.| |||.          |...:.:..|:|.|:.:
Human   209 GEYTVLPG--LDCTFSKGYQGLTNCMMAALPEDT----------VVFEKPVKTIHWNGSFQEAAF 261

  Fly   252 ------LTVRCWNGEVITADHVICTVSLGVLKEQHPKLFVPALPAAKVRAIEGLKLGTVDKFFLE 310
                  ::|.|.:|:...|.|||.||.||.|:|.....|.|.|||.|..||..:..||.:|.|||
Human   262 PGETFPVSVECEDGDRFPAHHVIVTVPLGFLREHLDTFFDPPLPAEKAEAIRKIGFGTNNKIFLE 326

  Fly   311 FENPPLPGDWPGFNCLWLKEDLEELR--ASEL--FWLESVFGF--YPVSRQPRILQGWIIGPHAR 369
            ||.|....|......:|  ||...|.  |.||  .|...:.||  .|......:|.|:|.|..:.
Human   327 FEEPFWEPDCQLIQLVW--EDTSPLEDAAPELQDAWFRKLIGFVVLPAFASVHVLCGFIAGLESE 389

  Fly   370 HMETLTEERVLEGLLWLFRKF-----LPFETAHPVRMLRTQWHANPNFRGSYTFRSTYTDALRTG 429
            .||||::|.||..|..:.|:.     ||    .|..:||::||:.|..||||::.:..:..   |
Human   390 FMETLSDEEVLLCLTQVLRRVTGNPRLP----APKSVLRSRWHSAPYTRGSYSYVAVGSTG---G 447

  Fly   430 AWDLEA---PLQDVCGRPRLQFAGESTHKHFYSTVHGAVETGWREAERL 475
            ..||.|   |......:.::.||||:||:.||||.|||:.:|||||:||
Human   448 DLDLLAQPLPADGAGAQLQILFAGEATHRTFYSTTHGALLSGWREADRL 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7460	NP_649004.1	Amino_oxidase	32..476	CDD:396255	152/489 (31%)
PAOX	NP_690875.1	PLN02568	14..497	CDD:215308	160/504 (32%)