DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7460 and amx-3

DIOPT Version :9

Sequence 1:	NP_001261998.1	Gene:	CG7460 / 39973	FlyBaseID:	FBgn0036749	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	NP_001355373.1	Gene:	amx-3 / 184919	WormBaseID:	WBGene00000139	Length:	450	Species:	Caenorhabditis elegans

Alignment Length:	508	Identity:	136/508 - (26%)
Similarity:	210/508 - (41%)	Gaps:	116/508 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 RIVIVGAGSAGIAAATRLLDLGFRNVLLLEAEDRIGGRVHTIPFADNVVDLGAQWCHGEKGNVVY 81
            ::.|:|||.||:.:|.....:|. :..:.|..:||||||:...:.|..:..||::.:| ..|.||
Worm     3 KVCIIGAGLAGLRSAIHFEQVGI-DYTIFEGSNRIGGRVYPFEYQDGYLHFGAEYVNG-VDNEVY 65

  Fly    82 DKVKDLNLLEVTEPHYETFRCVRSNKEVLPDDL--ADQLKTIADMS---IPDRQAELLDFEGSLG 141
            :.|:..:|.:.|:|.              .|||  .||..:|..::   :|.:   :||......
Worm    66 NLVEKYDLFDKTKPR--------------TDDLWMLDQDNSITLVNGHLVPKK---ILDKFNDYI 113

  Fly   142 DYINMKYWKELAKLP--PIDRTIAEEFLEVFHKFEASVEAADH-LFEVSGKGHLEYWLCE----- 198
            .|:|:..:::..|:.  .::..|..:|:|    |...|...|| ::|.....:..|:..|
Worm   114 RYLNVALYEKSIKINQLSVENEINNQFIE----FLRDVPENDHEIYESLINVYKNYFQTEWSSPV 174

  Fly   199 GELLLN----WKDKGYKRFLKLLMKAPEDQSEDLG------ILKD--------HVRLNRRIAEIN 245
            |||.|:    |.|           ...|:.|..|.      ||||        ::|||..:  ||
Worm   175 GELSLSNLSIWDD-----------GTEEEDSAVLNKQGFYEILKDFRSKIPAGNIRLNCEV--IN 226

  Fly   246 WKGADELTVRCWNGEVITADHVICTVSLGVLKEQHPKLFVPALPAAKVRAIEGLKLGTVDKFFLE 310
            .|..:.:.|...||||:..|..|.|.|||.||:.|..||.|.|.:.|..||..:..|...|.|||
Worm   227 VKEEENIMVTLKNGEVLHFDACIVTCSLGYLKKHHKTLFTPQLTSVKQDAINRMGFGNNLKVFLE 291

  Fly   311 FENPPLPGDWPGFNCLWLKEDLEELRASELFWLESVFGFYPVSRQPRILQGWIIGPHAR------ 369
            :.:    ..|...|.:.:....|.         |....|.|.|....||..||.|...:
Worm   292 YSD----SWWNSLNTILILTHGEN---------EDFMVFQPSSWAENILLCWIAGSGPKKICDKT 343

  Fly   370 --HMETLTEERVLEGLLWLFRKFLPFETAHPVRMLRTQWHANPNFR-GSYTFRSTYTDALRTGAW 431
              .::.|.:..:.:.|    :.:|..:.:  |::.|..| .|..|. |||::   .|.....|
Worm   344 DFELKILLDTHLHDQL----KNYLDVKAS--VKIYRKNW-INDEFTLGSYSY---LTPGQIVG-- 396

  Fly   432 DLEAPLQDVC---------GRPRLQFAGESTHKHFYSTVHGAVETGWREAERL 475
                  :|:|         ..|.:.||||.|....|.|..|||.:|.|||.|:
Worm   397 ------EDICILAQPVLKDNNPVICFAGEHTDSTMYQTTVGAVRSGLREASRI 443

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7460	NP_001261998.1	Amino_oxidase	32..476	CDD:279874	129/493 (26%)
CG7460	NP_001261998.1	NAD_binding_8	33..>74	CDD:290186	11/40 (28%)
amx-3	NP_001355373.1	Amino_oxidase	11..443	CDD:366721	131/498 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D375579at33208
OrthoFinder	1	1.000	-	-		FOG0000632
OrthoInspector	1	1.000	-	-		mtm4748
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X429
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920