DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7460 and Maob

DIOPT Version :9

Sequence 1:	NP_001261998.1	Gene:	CG7460 / 39973	FlyBaseID:	FBgn0036749	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	NP_766366.2	Gene:	Maob / 109731	MGIID:	96916	Length:	520	Species:	Mus musculus

Alignment Length:	516	Identity:	131/516 - (25%)
Similarity:	201/516 - (38%)	Gaps:	127/516 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 IVIVGAGSAGIAAATRLLDLGFRNVLLLEAEDRIGGRVHTIPFADNV--VDLGAQWCHGEKGNVV 80
            :::||.|.:|:|||..|.|.|. :|::|||.||:|||.:||. ..||  ||||..:. |...|.:
Mouse     7 VIVVGGGISGMAAAKLLHDCGL-SVVVLEARDRVGGRTYTIR-NKNVKYVDLGGSYV-GPTQNRI 68

  Fly    81 YDKVKDLNLLEVTEPHYETFRCVRSNKEV-------------LP------------------DDL 114
            ....|:|.|        ||::.....:.:             .|                  |::
Mouse    69 LRLAKELGL--------ETYKVNEVERLIHFVKGKSYAFRGPFPPVWNPITYLDNNNLWRTMDEM 125

  Fly   115 ADQLKTIADMSIPDRQAELLDFEGSLGDYINMK------YWKELAKLPPIDRTIAEEFLEVFHKF 173
            ..::.:.|....|..:.         .||:.||      .|.:..|      .||..|:.:
Mouse   126 GQEIPSDAPWKAPLAEE---------WDYMTMKELLDKICWTKSTK------QIATLFVNL---- 171

  Fly   174 EASVEAADHLFEVSGKGHLEY-WLCEGEL-LLNWKDKGYKRFLKLLMKAPEDQSEDLGILKDHVR 236
              .|.|..|  |||....|.| ..|.|.. :::..:.|.:|  |.:..:.:.......||.|.|:
Mouse   172 --CVTAETH--EVSALWFLWYVKQCGGTTRIISTTNGGQER--KFIGGSGQVSERIKDILGDRVK 230

  Fly   237 LNRRIAEINWKGADELTVRCWNGEVITADHVICTVSLGVLKEQHPKLFVPALPAAKVRAIEGLKL 301
            |.|.:..|:..| :.:.|:..|.|:..|.:||..:...:..:.|   :.|.||..:.:.|..:.|
Mouse   231 LERPVIHIDQTG-ENVIVKTLNHEIYEAKYVISAIPPALGMKIH---YSPPLPMLRNQLISRVPL 291

  Fly   302 GTVDKFFLEFENPPLPGDWPGFNCLWLKED------LEELRASELFWLESV--FGFYPVSRQPRI 358
            |:|.|..:.::.|           .|.|:|      :|...|...:.|:..  .|.|..
Mouse   292 GSVIKCMVYYKEP-----------FWRKKDFCGTMVIEGEEAPIAYTLDDTKPDGTYAA------ 339

  Fly   359 LQGWIIGPHARHMETLTEERVLEGLLWLFRKFLPFETA-HPVRMLRTQWHANPNFRGSYT----- 417
            :.|:|:...||.:..||:|..|..|..|:.|.|..:.| .||......|.......|.||
Mouse   340 IMGFILAHKARKLVRLTKEERLRKLCELYAKVLNSQEALQPVHYEEKNWCEEQYSGGCYTTYFPP 404

  Fly   418 -FRSTYTDALRTGAWDLEAPLQDVCGRPRLQFAGESTHKHFYSTVHGAVETGWREA-ERLH 476
             ..:.|...||          |.|   .::.|||..|..|:...:.||||.|.|.| |.||
Mouse   405 GILTQYGRVLR----------QPV---GKIFFAGTETASHWSGYMEGAVEAGERAAREILH 452

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7460	NP_001261998.1	Amino_oxidase	32..476	CDD:279874	122/500 (24%)
CG7460	NP_001261998.1	NAD_binding_8	33..>74	CDD:290186	20/42 (48%)
Maob	NP_766366.2	NAD_binding_8	9..75	CDD:290186	30/68 (44%)
Maob	NP_766366.2	Amino_oxidase	14..451	CDD:279874	126/506 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839585
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S7858
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.790