DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7460 and Il4i1

DIOPT Version :9

Sequence 1:	NP_001261998.1	Gene:	CG7460 / 39973	FlyBaseID:	FBgn0036749	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	XP_006229253.1	Gene:	Il4i1 / 100360621	RGDID:	1304831	Length:	648	Species:	Rattus norvegicus

Alignment Length:	547	Identity:	132/547 - (24%)
Similarity:	191/547 - (34%)	Gaps:	166/547 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LSKTRQTARIVIVGAGSAGIAAATRLLDLGFRNVLLLEAEDRIGGRVHTIPFADN----VVDLGA 69
            |::|.:..::|:||||.||:.||..|.|.|.: |.:|||.:|||||:.|  |.|.    :.:|||
  Rat    60 LNRTSKPQKVVVVGAGVAGLVAAKVLSDAGHK-VTILEAGNRIGGRIFT--FRDEKTGWIGELGA 121

  Fly    70 -----------QWCHGEKGNVVYDKVKDLNLLEVTEPHYETFRCVRSNK------EVLPDDLADQ 117
                       |.|          :...|||.:.|:.....:..|:..|      |.:|:.|...
  Rat   122 MRMPSSHRILHQLC----------RSLGLNLTQFTQYDENAWTEVKGVKLRNYVVEKMPEKLGYD 176

  Fly   118 L------------------KTIADMSIPDRQAELLDFEGSLGDYINMKYWKELAKLPPIDRTIAE 164
            |                  |.|.|:.:             ||....|..:.|        .|:.|
  Rat   177 LNHRERGHSPEDIYQMALNKAIKDVKV-------------LGCKKAMNMFSE--------HTLLE 220

  Fly   165 EFLEVFHKFEASVEAADHLFEVSGKGHLEY------WLCEGELLLNWKDKGYKRFL---KLLMKA 220
            ..|:..:..:.:|:....:....|..:|..      ..|..:.|      .|.|.:   .||.:|
  Rat   221 YLLKEGNLSQPAVQLLGDVMSKEGFFYLSLAEAFRAHACLSDRL------RYSRIVGGWDLLPRA 279

  Fly   221 PEDQSEDLGILKDHVRLNRRIAEINWKGADELTVRCWNG------EVITADHVICTVSLGVLKEQ 279
            .      |..|...|.||..:..|: :|..|:.|.....      ||:|||.|:.|.|...|:..
  Rat   280 L------LSSLSGTVLLNAPVVSIS-QGRHEVHVHFTTSLQSHSLEVMTADVVLLTASGPALQRI 337

  Fly   280 HPKLFVPALPAAKVRAIEGLKLGTVDKFFLEFENPPLPGDWPGFNCLWLKEDL-----EELRASE 339
            .   |.|.|...:..|:..|......|.||.|..|           .|.:|.:     ...|.|.
  Rat   338 S---FSPPLTRKRQEALRALHYVAASKVFLSFHRP-----------FWHEEHIMGGHSNTDRPSR 388

  Fly   340 LFWLESVFGFYPVSRQPRILQG---W--IIGPHARHMETLTEERVLEGLLWLFRKFLPFETAH-P 398
            |.       |||...:..:|..   |  ...|.|......|...||:.|..|          | |
  Rat   389 LI-------FYPAPGEGSLLLASYTWSDAAAPFAGLSTEQTLHLVLKDLAAL----------HGP 436

  Fly   399 V-------RMLRTQWHANPNFRGSYTFRSTYTDALRTGAWDLEAPLQDVCGRPRLQFAGESTHKH 456
            |       |.:..:|..:|..:|.:..:.... ...|..:|...|.      .|:.||||.|
  Rat   437 VVYRLWDGRGVVKRWAEDPYSQGGFVVQPPLF-GQGTEDYDWSVPY------GRIYFAGEHT--- 491

  Fly   457 FYSTVHGAVET----GWREAERLHLYY 479
              :..||.|||    |.|.|.|::..|
  Rat   492 --ALPHGWVETAVKSGLRAALRINSNY 516

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7460	NP_001261998.1	Amino_oxidase	32..476	CDD:279874	120/519 (23%)
CG7460	NP_001261998.1	NAD_binding_8	33..>74	CDD:290186	20/55 (36%)
Il4i1	XP_006229253.1	Amino_oxidase	83..513	CDD:396255	120/519 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343438
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840