Protein Alignment Ccn and ccn3

DIOPT Version :10

• Sequence 1: NP_730294.1
• Gene: Ccn / 39972
• FlyBaseID: FBgn0052183
• Length: 470
• Species: Drosophila melanogaster
• Sequence 2: XP_002938019.1
• Gene: ccn3 / 100494006
• XenbaseID: XB-GENE-1013046
• Length: 344
• Species: Xenopus tropicalis
• Alignment Length: 277
• Identity: 78/277 - (28%)
• Similarity: 111/277 - (40%)
• Gaps: 87/277 - (31%)

  Fly    40 NCSVGNTTFAHGVTFKLDCKTQCVCENGRHACSTLCPNE-QLPAPEDTISCRSPRLVEVPGHCCK 103
            ||......:.:..||:..||..|.|.||...|...|..: .||.|:    |..||.|:|||.||:
 Frog    94 NCIFDGVVYRNRATFQPSCKYHCTCLNGHIGCVPRCNLDLMLPGPD----CPFPRRVKVPGECCE 154

  Fly   104 MWLCEN---------------PTA-------DVYATCHNSTTSGNWTACSRSCGLGTATRHTTTH 146
            .|:|::               |.|       |:: ||...||  .|:|||::||:|.::|.|..:
 Frog   155 KWVCDSKEEMAIGGFAMAAYRPEATLGIDASDMF-TCIAQTT--EWSACSKTCGMGVSSRVTNRN 216

  Fly   147 AGCHQLSNLRLCENRRCDKDDHEDNKWSRSRPLTHKRKQHRAHSHSHQRYHHHKEHEEPA-HRIR 210
            ..|.....:|||..|.|:                                      |||. |..:
 Frog   217 PRCEMQKQIRLCMVRPCE--------------------------------------EEPGWHMEK 243

  Fly   211 KGHEC-RSIQRLGPARIRLGECVSRKLYRPKLCGRCHRGVKCCAPAVSTTIQVELLCPLNAVDPI 274
            ||..| |..:...|..:....|.|.:.|:||.||:|..| :||.|..:.|:.||..||
 Frog   244 KGKRCVRMRKTTKPIHLHYKNCSSVQPYKPKFCGQCSDG-RCCTPHTTKTMHVEFECP------- 300

  Fly   275 NYVQRRQANKKRQMKEP 291
                     :||.:|:|
 Frog   301 ---------QKRIIKKP 308

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ccn	NP_730294.1	VWC	41..104	CDD:450195	23/63 (37%)
		TSP1_spondin	118..163	CDD:480609	17/44 (39%)
ccn3	XP_002938019.1	IGFBP	21..74	CDD:459717
		VWC	95..155	CDD:214564	23/63 (37%)
		TSP1_CCN	190..233	CDD:465952	17/44 (39%)
		CT	253..322	CDD:214482	22/73 (30%)