Protein Alignment CG6052 and PDR12

DIOPT Version :9

• Sequence 1: NP_649002.3
• Gene: CG6052 / 39971
• FlyBaseID: FBgn0036747
• Length: 1725
• Species: Drosophila melanogaster
• Sequence 2: NP_015267.1
• Gene: PDR12 / 856049
• SGDID: S000005979
• Length: 1511
• Species: Saccharomyces cerevisiae
• Alignment Length: 1381
• Identity: 257/1381 - (18%)
• Similarity: 463/1381 - (33%)
• Gaps: 496/1381 - (35%)

  Fly   409 ERLSLMSKLLISLI------FSNSALGFGIHVIVMW----------EGTGEGITWRNMFHPVSTD 457
            |||..|::::....      |..:.|.|.:..::.:          |....||.::|
Yeast    62 ERLESMARVISHKTKKEMDSFEINDLDFDLRSLLHYLRSRQLEQGIEPGDSGIAFKN-------- 118

  Fly   458 DSLTLFYIIMTMSFGSIMFISICLYVEQVFPGEYGVPRRWNFMCHKNYWRQYVPSLNIVPSFQTI 522
              ||...:..:.::|.        .||::|.....:|..   :..|...:..||..||:
Yeast   119 --LTAVGVDASAAYGP--------SVEEMFRNIASIPAH---LISKFTKKSDVPLRNII------ 164

  Fly   523 LHGSAKAKSCRRAREVGIQLFNLQKNYGKLKAVKGISLKMHRNEITVLLGHNGAGKTTTINMITG 587
                   ::|....|.|..||                          ::|..|||.:|.:..::|
Yeast   165 -------QNCTGVVESGEMLF--------------------------VVGRPGAGCSTFLKCLSG 196

  Fly   588 IVK---PTSGTAIVNGYDIRTHLAKARESLGICPQNNILFKEMSVRDHIIFFSKLKGIR------ 643
            ...   ...|....:|.|....::|.:..:..||:.:..|.:::|::.|.|..|.|..|
Yeast   197 ETSELVDVQGEFSYDGLDQSEMMSKYKGYVIYCPELDFHFPKITVKETIDFALKCKTPRVRIDKM 261

  Fly   644 -GTKAVENEVGKYMTMLKLQDKSYVA------AKNLSGGMKRKLSLCCALCGNAKVVLCDEPSSG 701
             ..:.|:|....:.|:..|: .:|..      .:.:|||.::::||..|...||.:...|..:.|
Yeast   262 TRKQYVDNIRDMWCTVFGLR-HTYATKVGNDFVRGVSGGERKRVSLVEAQAMNASIYSWDNATRG 325

  Fly   702 IDAAGRRSLWDLLQSEKDGRTILLTTHYMDEADV------------LGDRIAILSEGKLQCQGTS 754
            :||:         .:.:..:.|...|:.::.:.:            |.|:..:|..|:      .
Yeast   326 LDAS---------TALEFAQAIRTATNMVNNSAIVAIYQAGENIYELFDKTTVLYNGR------Q 375

  Fly   755 FYLKKRFG-----TGYLLVCIMQSGCDVGAVTQLIRKYVPPIKPERVLGTELTYRLPTEYSKKFA 814
            .|    ||     .||    ..:.|.               :||.|:...|....:..::..:..
Yeast   376 IY----FGPADKAVGY----FQRMGW---------------VKPNRMTSAEFLTSVTVDFENRTL 417

  Fly   815 ELLQDLDEKCAQLQLVGYGLSGATLEDVFMAVNTDKRVQGGAEGPPVDGSIDFKELV--FD---- 873
            ::....::|..:        |.:..|:.::                  .|.|::||:  :|
Yeast   418 DIKPGYEDKVPK--------SSSEFEEYWL------------------NSEDYQELLRTYDDYQS 456

  Fly   874 ----SKTREKRRIRRCFMFWQALFLKKFYTTTRNYW-------LLGIQLVLPIAVMALTILNSRG 927
                ::||::..:.:.....|.......|..  |||       :.|.|.|             :|
Yeast   457 RHPVNETRDRLDVAKKQRLQQGQRENSQYVV--NYWTQVYYCMIRGFQRV-------------KG 506

  Fly   928 GRIYYELPAMPISINQYSSAYVV-------LEDNTTDKT-SSLADAYSKHLEHYARRCTLLRTGD 984
            ...|.::         |.|::::       :.....||: |:.|.|||:              |.
Yeast   507 DSTYTKV---------YLSSFLIKALIIGSMFHKIDDKSQSTTAGAYSR--------------GG 548

  Fly   985 LKFEDYILSHDVNHSRRIDFHFLAGLTVSENNFIVWLNNKPLHTAPLTLNLLHNALAIKLLGQDA 1049
            :.|  |:|.          |..:..|....|:|    :::|:.....:.::.|      |..:..
Yeast   549 MLF--YVLL----------FASVTSLAEIGNSF----SSRPVIVKHKSYSMYH------LSAESL 591

  Fly  1050 STYVTNEPLPYSDDTRTLRLNKGQVLGAEISINLSLTMCFIT-----------AF--YAIPIIRE 1101
            ...:|..|..:                  ::|   :.:|.||           ||  |.:.::..
Yeast   592 QEIITEFPTKF------------------VAI---VILCLITYWIPFMKYEAGAFFQYILYLLTV 635

  Fly  1102 RETRAKLLQFL-----SGVDVCAYWTSHIVWDYLVFVLSALSSILTIAAFKEIGYITPLDLSRYF 1161
            ::..:.:.:|:     ||||      :|.|....|.:|...:           |::.|:....::
Yeast   636 QQCTSFIFKFVATMSKSGVD------AHAVGGLWVLMLCVYA-----------GFVLPIGEMHHW 683

  Fly  1162 YMLLIFGFPGIMLSYAASGCFS--------------DAATGFTRISIINTLMGTGLFLMFMTLNF 1212
            ...|.|..|   |:||.....|              .:..|:..|||.|
Yeast   684 IRWLHFINP---LTYAFESLVSTEFHHREMLCSALVPSGPGYEGISIAN---------------- 729

  Fly  1213 EAFQLKDVAEKLAWYFRLS-PHYSLASSTHSIHIGYNIRRGCSIGGIRKLPKQLRCRNVPICCDI 1276
               |:.|.|..:.....:| ..|.|    |..|..|.
Yeast   730 ---QVCDAAGAVKGNLYVSGDSYIL----HQYHFAYK---------------------------- 759

  Fly  1277 PGYYGWRKPGVLVEITYMIMLGSTLFLLIVMHDAKVCNLIAEKLGNCFSKRKRVEGGTSI----- 1336
               :.||..||.:..|:    |..:|.:|          ::|.|       |.||||..:
Yeast   760 ---HAWRNWGVNIVWTF----GYIVFNVI----------LSEYL-------KPVEGGGDLLLYKR 800

  Fly  1337 --------EN-DSVVAEQRVVREMINSGRKDVPLLV------------YKISKRYRSKLAVKAIS 1380
                    || |:..|.:..:.|.:|....|:..::            |.|.....::..:..:.
Yeast   801 GHMPELGTENADARTASREEMMEALNGPNVDLEKVIAEKDVFTWNHLDYTIPYDGATRKLLSDVF 865

  Fly  1381 FHVPHAECFGLLGINGAGKTSTFKMLAGDEKITSGEAYIDGTNISTHK-----VYRKIGYCPQFD 1440
            .:|...:...|:|.:|||||:...:||  ::|..|  .|.|..:...|     ..|..||..|.|
Yeast   866 GYVKPGKMTALMGESGAGKTTLLNVLA--QRINMG--VITGDMLVNAKPLPASFNRSCGYVAQAD 926

  Fly  1441 ALFEDLTGRETLNIYCLLR-------GVQRRHVTPICWGLAISFGFAKHMDKQTKHYSGGNRRKL 1498
            ....:|:.||:|.....||       ..:..:|..|...|.:.......:.|..:..:...|:||
Yeast   927 NHMAELSVRESLRFAAELRQQSSVPLEEKYEYVEKIITLLGMQNYAEALVGKTGRGLNVEQRKKL 991

  Fly  1499 STAISVLGNPS-VLYLDEPTSGMDPAARRQLWQIIGLIRT---AGKSIVLTSHSMDECEALCSRL 1559
            |..:.::..|| :|:|||||||:|   .:..|.|:..:|.   :|:||:.|.|...
Yeast   992 SIGVELVAKPSLLLFLDEPTSGLD---SQSAWSIVQFMRALADSGQSILCTIHQPS--------- 1044

  Fly  1560 AIMVDGEFKCLGSVQSLKNQFSKGLILKVKVKHKKKTFQRVVEDSSSSNDKKSISETDLKFLQMA 1624
                          .:|..||.:.|:||   |..|..:         ..|....|||.||:.:..
Yeast  1045 --------------ATLFEQFDRLLLLK---KGGKMVY---------FGDIGPNSETLLKYFERQ 1083

  Fly  1625 SVME----SSQADRIL 1636
            |.|:    .:.|:.||
Yeast  1084 SGMKCGVSENPAEYIL 1099

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6052	NP_649002.3	rim_protein	21..>54	CDD:130324
		rim_protein	<149..1709	CDD:130324	257/1381 (19%)
PDR12	NP_015267.1	3a01205	89..1468	CDD:273362	251/1354 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	105	1.000	Inparanoid score	I1418
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050