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Protein Alignment CG6052 and PDR15

DIOPT Version :9

Sequence 1:	NP_649002.3	Gene:	CG6052 / 39971	FlyBaseID:	FBgn0036747	Length:	1725	Species:	Drosophila melanogaster
Sequence 2:	NP_010694.1	Gene:	PDR15 / 852015	SGDID:	S000002814	Length:	1529	Species:	Saccharomyces cerevisiae

Alignment Length:	1369	Identity:	266/1369 - (19%)
Similarity:	468/1369 - (34%)	Gaps:	457/1369 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   514 NIVPSFQTILHGSAKAKSCRRAREVGIQLFNLQKNYGKLKAVKGISLKMHRNEITVLLGHNGAGK 578
            ||||...|                .|::|....|.....:.:|.:...::..|:.|:||..|:|.
Yeast   161 NIVPKLLT----------------KGLRLLKPSKEEDTFQILKPMDGCLNPGELLVVLGRPGSGC 209

  Fly   579 TTTINMIT----GIVKPTSGTAIVNGY---DIRTHLAKARESLGICPQNNILFKEMSVRDHIIFF 636
            ||.:..|:    |...........||.   |||.|.   |..:....:::|....::|...:...
Yeast   210 TTLLKSISSNSHGFKIAKDSIVSYNGLSSSDIRKHY---RGEVVYNAESDIHLPHLTVYQTLFTV 271

  Fly   637 SKLKGIRG-TKAVENEV-GKYMTMLKLQDKSYVAA------------KNLSGGMKRKLSLC-CAL 686
            :::|..:. .|.|:.|. ..::|.:.:  .:|..:            :.:|||.::::|:. .|:
Yeast   272 ARMKTPQNRIKGVDREAYANHVTEVAM--ATYGLSHTRDTKVGNDLVRGVSGGERKRVSIAEVAI 334

  Fly   687 CGNAKVVLCDEPSSGIDAAGRRSLWDLLQSEKD-GRTILLTTHYMDEADV--LGDRIAILSEGKL 748
            || |:....|..:.|:|:|........|:::.| |:|......|....|.  |.|::.:|.:|..
Yeast   335 CG-ARFQCWDNATRGLDSATALEFIRALKTQADIGKTAATVAIYQCSQDAYDLFDKVCVLDDGYQ 398

  Fly   749 QCQGTSFYLKKRF-GTGYLLVCIMQSGCDVGAVTQLIRKYVPPIK------------PERVLGTE 800
            ...|.:...||.| ..||                     |.||.:            .||::..|
Yeast   399 LYFGPAKDAKKYFQDMGY---------------------YCPPRQTTADFLTSITSPTERIISKE 442

  Fly   801 LT---YRLP------TEY---SKKFAELLQDLDEKCAQLQLVGYGLSGATLEDVFMAVNTDKRVQ 853
            ..   .|:|      .||   |:.:..|::|:|               :|||.     |||
Yeast   443 FIEKGTRVPQTPKDMAEYWLQSESYKNLIKDID---------------STLEK-----NTD---- 483

  Fly   854 GGAEGPPVDGSIDFKELVFDS-KTREKRRIRRCFMFWQALFLKKFYTTTRNYWLL----GIQL-- 911
                        :.:.::.|: ..::.:|......:.....::..|...||:|.:    .:.|
Yeast   484 ------------EARNIIRDAHHAKQAKRAPPSSPYVVNYGMQVKYLLIRNFWRMKQSASVTLWQ 536

  Fly   912 VLPIAVMALTILNSRGGRIYYELPAMPISINQYSSAYVVLEDNTTDKTSSLADAYSKHLEHYARR 976
            |:..:|||..:     |.::|:                |::.|.|.
Yeast   537 VIGNSVMAFIL-----GSMFYK----------------VMKKNDTS------------------- 561

  Fly   977 CTLLRTGDLKFEDYILSHDVNHSRRIDFHFLAGLTVSENNFIVWLNNKPLHTAPLTLNLLHNALA 1041
                                      .|:|                    ..|.:...:|.||.:
Yeast   562 --------------------------TFYF--------------------RGAAMFFAILFNAFS 580

  Fly  1042 IKLLGQDASTYVTNEPLPYSDDTRTLRLNK------GQVLGAEISINLSLTMCFITAFYAIPIIR 1100
            ..|  :..|.|.|.   |.::..||..|..      ..|| :|:...|...:||...||.:...|
Yeast   581 CLL--EIFSLYETR---PITEKHRTYSLYHPSADAFASVL-SEMPPKLITAVCFNIIFYFLVDFR 639

  Fly  1101 ERETRAKLLQFLSGVDVCAYWTSHIVWDYLVFVLSALSSILTIAAFKEIGYITPLDLSRYFYMLL 1165
             |........||..| :..:..||:                    |:.:|     .|::.....:
Yeast   640 -RNGGVFFFYFLINV-IATFTLSHL--------------------FRCVG-----SLTKTLQEAM 677

  Fly  1166 IFGFPGIMLSYAASGCFSDAATGFTRISIINT-LMGTGLFLMF---MTLNFEAFQLKDVAEK--- 1223
            :   |..||..|.|     ..|||   :|..| ::|..:::.:   :...||:..:.:..::
Yeast   678 V---PASMLLLAIS-----MYTGF---AIPKTKILGWSIWIWYINPLAYLFESLMINEFHDRRFP 731

  Fly  1224 LAWYFRLSPHYSLASSTHSIHIGYNIRRGCSIGGIRKLPKQLRCRNVPICCDIPG---------- 1278
            .|.|....|.|...:.|         :|.||..|.                 .||
Yeast   732 CAQYIPAGPAYQNITGT---------QRVCSAVGA-----------------YPGNDYVLGDDFL 770

  Fly  1279 --------YYGWRKPGVLVEITYMIMLGSTLFLL-------------IVMHDAKVCNLIAEKLGN 1322
                    .:.||  |..:.:.|::.......:|             :|...:|:..|  :|.|.
Yeast   771 KESYDYEHKHKWR--GFGIGMAYVVFFFFVYLILCEYNEGAKQKGEMVVFLRSKIKQL--KKEGK 831

  Fly  1323 CFSKRK--RVEGGTSIENDSVVAEQRVV---REMINSGRKDVPL-------------LVYKISKR 1369
            ...|.:  .:|.......||...|::::   .|..:|...:..|             |.|.:..:
Yeast   832 LQEKHRPGDIENNAGSSPDSATTEKKILDDSSEGSDSSSDNAGLGLSKSEAIFHWRDLCYDVPIK 896

  Fly  1370 YRSKLAVKAISFHVPHAECFGLLGINGAGKTSTFKMLAGDEKIT----SGEAYIDGTNISTHKVY 1430
            ...:..:..:...|.......|:|.:|||||:....||  |::|    :|..::|| .:......
Yeast   897 GGQRRILNNVDGWVKPGTLTALMGASGAGKTTLLDCLA--ERVTMGVITGNIFVDG-RLRDESFP 958

  Fly  1431 RKIGYCPQFDALFEDLTGRETLNIYCLLR-------GVQRRHVTPICWGLAISFGFAKHMDKQTK 1488
            |.||||.|.|...:..|.||:|.....||       ..:.|:|..:          .|.::.|
Yeast   959 RSIGYCQQQDLHLKTATVRESLRFSAYLRQPSSVSIEEKNRYVEEV----------IKILEMQ-- 1011

  Fly  1489 HYSGG------------NRRKLSTAISVLGNPSVL-YLDEPTSGMDPAARRQLWQIIGLIRTAGK 1540
            .||..            .|::|:..:.:...|.:| :|||||||:|........|::..:.|.|:
Yeast  1012 QYSDAVVGVAGEGLNVEQRKRLTIGVELAARPKLLVFLDEPTSGLDSQTAWDTCQLMRKLATHGQ 1076

  Fly  1541 SIVLTSHS-----MDECEALCSRLAIMVDGEFKCLGSV----QSLKNQF-SKGL----------- 1584
            :|:.|.|.     |.:.:.|   |.:...|:....|.:    :::.:.| |||.
Yeast  1077 AILCTIHQPSAILMQQFDRL---LFLQKGGQTVYFGDLGEGCKTMIDYFESKGAHKCPPDANPAE 1138

  Fly  1585 -ILKV----KVKHKKKTFQRVVEDSSSSNDKKSISETDLKFLQMASVMESSQADRILKVNRFISK 1644
             :|:|    ...|..:.:..|..   :|::.|::.| :|.:      ||.:...|        ||
Yeast  1139 WMLEVVGAAPGSHATQDYNEVWR---NSDEYKAVQE-ELDW------MEKNLPGR--------SK 1185

  Fly  1645 EIPDAELKEEYNGLITYYIPHSKTLSKIFQLLETNSHKLNIEDYL---IMQTRLEEIFLDFA-SK 1705
            | |.||..:.:...: ||.....|: ::||      ......|||   .:.|...::|:.|. .|
Yeast  1186 E-PTAEEHKPFAASL-YYQFKMVTI-RLFQ------QYWRSPDYLWSKFILTIFNQVFIGFTFFK 1241

  Fly  1706 RDSS 1709
            .|.|
Yeast  1242 ADRS 1245

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.