DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6052 and ABCA12

DIOPT Version :9

Sequence 1:	NP_649002.3	Gene:	CG6052 / 39971	FlyBaseID:	FBgn0036747	Length:	1725	Species:	Drosophila melanogaster
Sequence 2:	NP_001318859.1	Gene:	ABCA12 / 836292	AraportID:	AT5G61700	Length:	917	Species:	Arabidopsis thaliana

Alignment Length:	971	Identity:	236/971 - (24%)
Similarity:	431/971 - (44%)	Gaps:	217/971 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 WDKLKLLMWKNWILQ----WNQKMQIVFALVLPVLFLCLILVLRIIVLPEKMDEIRYPTVSISDL 79
            |.:...|:.||...|    |..     ..|:|..|||||||    :.:.:.:|.:   ...:||:
plant    10 WTQANALLRKNLTYQRKHIWTN-----VRLILVPLFLCLIL----LAIQQVLDAL---MKGVSDM 62

  Fly    80 NLYMRMVPLGNRILHENGSLNIPRNFLCYTPNNPINSAIVGATAIRLRLLGTRAYD--------- 135
            :             :..|::.:|.. :|..||.|....::......||.:.|..:.
plant    63 S-------------NCGGNVTLPGG-ICPIPNPPSLPPMLQIPQHELRSVKTDFFSYKDLPDKLC 113

  Fly   136 --------TALHMEQDMVLHNFLAGVQFEDNENVNTND---------------AG---------- 167
                    |.|.....:.|...|:...|..:..||::|               ||
plant   114 RETGSCPVTILFTGDKLPLGKALSANIFSTSFVVNSSDLLPTLANNVLGSTEAAGEDNYEDPGIA 178

  Fly   168 -----------------YPLNLNYSLRFPSELRTMQGPII--------------DTWR------T 195
                             :||:|.   :..:.::.:||..:              .:||      .
plant   179 SDLPIYSIQPSCSANSTWPLSLG---QIQTAVKCVQGLCLWRNNSVEVNDELFKGSWRGNPAGMP 240

  Fly   196 SRLFLSYDTSGSRNRLDNDGGVPVGY---IREGFLPIQ-----------HALTMSWLALASGVTD 246
            :.:..:||...:..:..|   |.:.|   ..:.|...|           :.::.::|....| ..
plant   241 NEIVAAYDLMSTDRKNFN---VTIWYNSTYNDEFATGQALKLVRVPRSINLISNAYLKFLKG-PG 301

  Fly   247 TGIPAIHLQRFPYRAYTYDQLLSGLRQLLPFVILLSFIYPASTVTKYVTSEKELQLKEIMKLIGV 311
            |.|....|:..|......:|.::.|...|.|..::..::|  .:...:..||:.:|:.|||:.|:
plant   302 TRILFEFLKEVPKEETKMNQDIASLLGPLFFTWVVLLLFP--VILTSLVYEKQERLRIIMKMHGL 364

  Fly   312 HNWLHWVAWFVKSYIMLMLVVFLIMSLI----MVKFYASVAVLTF--SSWVPVLLFLHTYVVTSV 370
            .:..:|         |:....||.:|::    :|.|.:::.:..|  :.:....:|...|....:
plant   365 GDGPYW---------MISYAYFLTISMLYVISLVGFGSAIGLKYFRRNDYSIQFVFYFIYSNLQI 420

  Fly   371 CLCFMLAVLFSKASTASAVAAIFWFLTYIPYSFGYYYYERL----SLMSKLLISL-IFSNSALGF 430
            .|.|:::.:|||..|.:.:|   :.|.|.....|.:.::::    |...:.:::: ::...:|..
plant   421 SLAFLVSSIFSKVKTVTVIA---YILVYGTGLLGSFLFQKMIETQSFPEEWILAMELYPGFSLYR 482

  Fly   431 GIHVIVMWEGTGEGITWRNMFHPVSTDDSLTLFYIIMTMSFGSIMFISICLYVEQVF-PGEY--- 491
            |::....:...|.|:.|:::     :|..:...:.||::.:  .:.:.:..|::||| .|::
plant   483 GLYEFSQYASRGNGMKWQDL-----SDSGMGEVFCIMSVEW--FLALIVAYYIDQVFTSGKHPFF 540

  Fly   492 ----------GVPRRWNFMCHKNYWRQYVPSLNIVPSFQTIL----HG-SAKAKSCRRAREVG-- 539
                      .:|||              |::..:.|.:..:    |. :.:.:|.::.|..|
plant   541 FLVNLFKSPSSLPRR--------------PTVQRLDSKRVFIDMDKHDVTQERESVQKLRNEGST 591

  Fly   540 ---IQLFNLQKNY-GK-----LKAVKGISLKMHRNEITVLLGHNGAGKTTTINMITGIVKPTSGT 595
               |...||:|.| |:     ..||:|:.|.:...|...:||.||||||:.|:|:||::||:|||
plant   592 GHAILCDNLKKVYPGRDGNPPKMAVRGLYLSVSSGECFGMLGPNGAGKTSFISMMTGLLKPSSGT 656

  Fly   596 AIVNGYDIRTHLAKARESLGICPQNNILFKEMSVRDHIIFFSKLKGIRG---TKAVENEVGKYMT 657
            |:|.|.||...:.|...|:|:|||:::|::.::.|:|::|:.:||.|:|   |:|||..: |.::
plant   657 ALVQGLDICKDMNKVYTSMGVCPQHDLLWETLTGREHLLFYGRLKNIKGSDLTQAVEESL-KSVS 720

  Fly   658 MLK--LQDKSYVAAKNLSGGMKRKLSLCCALCGNAKVVLCDEPSSGIDAAGRRSLWDLLQSEKDG 720
            :..  :.||   .|.|.||||||:||:..:|.||.|||..||||:|:|.|.|::||::::..|..
plant   721 LYDGGVGDK---PAGNYSGGMKRRLSVAISLIGNPKVVYLDEPSTGLDPASRKNLWNVIKRAKQN 782

  Fly   721 RTILLTTHYMDEADVLGDRIAILSEGKLQCQGTSFYLKKRFGTGYLLVCIMQSGCDVGAVTQLIR 785
            ..|:||||.|:||:.|.||:.|..:|.|||.|.|..||.|:|..|:......|..: ..|.:|:.
plant   783 TAIILTTHSMEEAEFLCDRLGIFVDGGLQCIGNSKELKSRYGGSYVFTMTTSSKHE-EEVERLVE 846

  Fly   786 KYVPPIKPERVLGTELTYRLPTEYSKKFAELLQDLDEKCAQLQLVGYGLSGATLEDVFMAV 846
            ...|..|....|.....:.||.: ..:.||:.:.:::..|...:..:||:..||||||:.|
plant   847 SVSPNAKKIYHLAGTQKFELPKQ-EVRIAEVFRAVEKAKANFTVFAWGLADTTLEDVFIKV 906

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6052	NP_649002.3	rim_protein	21..>54	CDD:130324	11/36 (31%)
CG6052	NP_649002.3	rim_protein	<149..1709	CDD:130324	206/820 (25%)
ABCA12	NP_001318859.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000051
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100045
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810