DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6052 and ABCA6

DIOPT Version :9

Sequence 1:	NP_649002.3	Gene:	CG6052 / 39971	FlyBaseID:	FBgn0036747	Length:	1725	Species:	Drosophila melanogaster
Sequence 2:	NP_001327229.1	Gene:	ABCA6 / 823931	AraportID:	AT3G47770	Length:	926	Species:	Arabidopsis thaliana

Alignment Length:	987	Identity:	246/987 - (24%)
Similarity:	415/987 - (42%)	Gaps:	246/987 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 LMWKNWILQ----WNQKMQIVFALVLPVLFLCLILVLRIIVLPEKMD------------------ 67
            |..||...|    |:....||..|.|.|:.:|:..|...:| ...:|
plant    16 LFKKNLTYQKRNIWSNVRLIVIPLYLCVVLVCIQAVFDSLV-NNSVDNQCGCRCADDDKNGDGKC 79

  Fly    68 EIRYPTVSISDLNLYM--------RMVPLGNRILHENGSLNIPRNFLCYTPNNPINSAIVG---- 120
            ||:...:..|..|..:        .::||    ||...|:|  |:....|.:.|:...:.|
plant    80 EIKSCGLQYSSQNQAVFCAFPNPPPLLPL----LHIPPSVN--RDSCQRTGSCPVTILVTGNNQS 138

  Fly   121 -ATAIRLRLLGTRAYDTALHMEQDMVLHNFLAGVQFEDNENVNTN--DAGY-------------- 168
             .|.:...||.|   ...::...|:.|.|....|....:|...||  |.|.
plant   139 LGTTLSENLLST---SFTVNSSSDLFLRNLAYNVLSTTSETDYTNYRDPGIYSDLPIFNIQPQCT 200

  Fly   169 P---LNLNY---SLRFPSELRTMQGPIIDTWRTSRLFLSYDTSGSRNRLDNDGGVPVGYIREGFL 227
            |   |:|::   .|.|..|:|.:||  ::.||.:.|.:            ||      .|.:||.
plant   201 PATILSLSFRQPPLEFHKEVRCVQG--LNLWRNNSLEV------------ND------EIFKGFR 245

  Fly   228 PIQHALTMSWLALASGVTDTGIPAIHLQRFPYRAY-----------------------TYDQLLS 269
            ...|...::.:|.|..:.:|.....::..:.|..|                       .|.|.|.
plant   246 KENHEEIINEVAAAYDLLNTDRNKFNVTIWYYTTYKGDLQDWRVKYVRVPRSVNMVSNAYLQFLR 310

  Fly   270 G-------------------LRQ---------------LLPF-VILLSFIYPASTVTKYVTSEKE 299
            |                   ||.               ||.| |||.|.:|           ||:
plant   311 GPGTKILFDFVKEMPKQETRLRMDMASLIGPIFFTWVILLLFPVILTSLVY-----------EKQ 364

  Fly   300 LQLKEIMKLIGVHNWLHWV---AWFVKSYIMLMLVVFLIMSLIMVKFYASVAVLTFSSWVPVLLF 361
            .:|:.|||:.|:.:..:|:   |:|:....:.::.:.:..|.|.:||:      .|:.:....:|
plant   365 QRLRIIMKMHGLGDAPYWMISYAYFLAISTLYIVCLMIFGSAIGLKFF------RFNDYTIQFMF 423

  Fly   362 LHTYVVTSVCLCFMLAVLFSKASTASAVAAIFWFLTYIPYSFGY-YYYERLSLMSK-LLISLIFS 424
            ...|:...:.:.|:::..||||.|||.||.|:.|.:.:..:|.: :..|.||...: :.:..::.
plant   424 YFLYINLQISIAFLVSSAFSKAVTASVVAYIYVFGSGLLGAFLFQFLIESLSFPRRWIFVMELYP 488

  Fly   425 NSALGFGIHVIVMWE-----GTGEGITWRNMFHPVSTDDSLTLFYIIMTMSFGSIMFISICLYVE 484
            ..:|..|::....:.     ...:|:.|:: |...:.|:..|:..:..      ::.:....|::
plant   489 GFSLYRGLYEFSQYAFQRNLNGRDGMKWKD-FRGSAMDEVFTIIIVEW------VVALVATYYID 546

  Fly   485 QVFPGEYG-------------VPRRWNFMCHKNYWRQYVPSLNIVPSFQTILHGSAKAKSCRRAR 536
            :|......             .|:..:|...::.....:..|:::...:|:     |.....|::
plant   547 RVSSSSKDTFAFLKNPFKLSPTPQMLSFQKERSDVSVEMEKLDVIQEKETV-----KQLIFERSK 606

  Fly   537 EVGIQLFNLQKNY-------GKLKAVKGISLKMHRNEITVLLGHNGAGKTTTINMITGIVKPTSG 594
            ..||...||:|.|       .|| ||.|:||.:...|...:||.||||||:.|||:||:|||:||
plant   607 NHGIVCDNLKKVYQGRDGNPPKL-AVCGLSLAVPSGECFGMLGPNGAGKTSFINMMTGLVKPSSG 670

  Fly   595 TAIVNGYDIRTHLAKARESLGICPQNNILFKEMSVRDHIIFFSKLKGIRG---TKAVENEV---- 652
            :|.|.|.||...:.|...|:|:|||:::|::.::.::|::|:.:||.::|   .:|||..:
plant   671 SAFVQGLDICKDMDKVYISMGVCPQHDLLWETLTGKEHLLFYGRLKNLKGHDLNQAVEESLKSVN 735

  Fly   653 -----------GKYMTMLKLQDKSYVAAKNLSGGMKRKLSLCCALCGNAKVVLCDEPSSGIDAAG 706
                       |||                 ||||||:||:..:|.|:.|||..||||:|:|.|.
plant   736 LFHGGVADIPAGKY-----------------SGGMKRRLSVAISLIGSPKVVYMDEPSTGLDPAS 783

  Fly   707 RRSLWDLLQSEKDGRTILLTTHYMDEADVLGDRIAILSEGKLQCQGTSFYLKKRFGTGYLLVCIM 771
            |.:||.:::..|....|:||||.|:||:.|.||:.|..:|:|||.|....||.|:|..|:|....
plant   784 RINLWTVIKRAKKHAAIILTTHSMEEAEFLCDRLGIFVDGRLQCIGNPKELKGRYGGSYVLTITT 848

  Fly   772 --QSGCDVGAVTQLIRKYVPPIKPERVLGTELTYRLPTEYSKKFAELLQDLDEKCAQLQLVGYGL 834
              :...||..:.|.:......|  ..:.||: .:..|.| ..:.:|:.|.::.......:..:|.
plant   849 SPEHEKDVETLVQEVSSNARKI--YHIAGTQ-KFEFPKE-EVRISEVFQAVENAKRNFTVFAWGF 909

  Fly   835 SGATLEDVFMAV 846
            :..||||||:.|
plant   910 ADTTLEDVFIKV 921

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6052	NP_649002.3	rim_protein	21..>54	CDD:130324	11/32 (34%)
CG6052	NP_649002.3	rim_protein	<149..1709	CDD:130324	211/828 (25%)
ABCA6	NP_001327229.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000051
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100045
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810