DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6052 and Abcg8

DIOPT Version :9

Sequence 1:	NP_649002.3	Gene:	CG6052 / 39971	FlyBaseID:	FBgn0036747	Length:	1725	Species:	Drosophila melanogaster
Sequence 2:	NP_080456.1	Gene:	Abcg8 / 67470	MGIID:	1914720	Length:	673	Species:	Mus musculus

Alignment Length:	359	Identity:	80/359 - (22%)
Similarity:	147/359 - (40%)	Gaps:	83/359 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly  1361 LLVYKISKRYRS-----KLAVKAISFHVPHAECFGLLGINGAGKTSTFKMLAG---DEKITSGEA 1417
            |..:||..|..|     :|.::.:||.|...:...::|.:|.|:.|...::.|   ..|:.||:.
Mouse    69 LAQFKIPWRSHSSQDSCELGIRNLSFKVRSGQMLAIIGSSGCGRASLLDVITGRGHGGKMKSGQI 133

  Fly  1418 YIDGTNISTHKVYRK-IGYCPQFDALFEDLTGRETLNIYCLLRGVQRRHVTPICWGLAISFGFAK 1481
            :|:| ..||.::.|| :.:..|.|.|..:||.||||.....:|             |..:|..|:
Mouse   134 WING-QPSTPQLVRKCVAHVRQHDQLLPNLTVRETLAFIAQMR-------------LPRTFSQAQ 184

  Fly  1482 HMDKQ----------------------TKHYSGGNRRKLSTAISVLGNPSVLYLDEPTSGMDPAA 1524
            . ||:                      .:..|||.||::|..:.:|.||.:|.|||||||:|...
Mouse   185 R-DKRVEDVIAELRLRQCANTRVGNTYVRGVSGGERRRVSIGVQLLWNPGILILDEPTSGLDSFT 248

  Fly  1525 RRQLWQIIGLIRTAGKSIVLTSHS-MDECEALCSRLAIMVDGEFKCLGSVQSLKNQFSKGLILKV 1588
            ...|...:..:....:.::::.|. ..:...|...:.:|..|....||:.|.:...|:
Mouse   249 AHNLVTTLSRLAKGNRLVLISLHQPRSDIFRLFDLVLLMTSGTPIYLGAAQQMVQYFT------- 306

  Fly  1589 KVKHKKKTFQRVVE--DSSSSNDKKSISETDLKFLQMASVMESSQADRILKVNRFISKEIPDAEL 1651
            .:.|....:....:  ...:|.|::| .|.::..::.|..:.:...:::...:.|:.|    ||.
Mouse   307 SIGHPCPRYSNPADFYVDLTSIDRRS-KEREVATVEKAQSLAALFLEKVQGFDDFLWK----AEA 366

  Fly  1652 KEEYNGLITYYIPHSKTLSKIFQLLETNSHKLNI 1685
            ||                      |.|::|.:::
Mouse   367 KE----------------------LNTSTHTVSL 378

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6052	NP_649002.3	rim_protein	21..>54	CDD:130324
CG6052	NP_649002.3	rim_protein	<149..1709	CDD:130324	80/359 (22%)
Abcg8	NP_080456.1	ABCG_White	71..296	CDD:213201	60/239 (25%)
		3a01204	89..664	CDD:273361	74/339 (22%)
		ABC2_membrane	402..606	CDD:279410
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910