Protein Alignment CG6052 and abca8

DIOPT Version :9

• Sequence 1: NP_649002.3
• Gene: CG6052 / 39971
• FlyBaseID: FBgn0036747
• Length: 1725
• Species: Drosophila melanogaster
• Sequence 2: XP_031749971.1
• Gene: abca8 / 549630
• XenbaseID: XB-GENE-1005441
• Length: 1619
• Species: Xenopus tropicalis
• Alignment Length: 1810
• Identity: 464/1810 - (25%)
• Similarity: 827/1810 - (45%)
• Gaps: 351/1810 - (19%)

  Fly    25 LMWKNWILQWNQKMQIVFALVLPVLFLCLILVLRIIVLPEKMDEIRYPTVSISDLNLYMRMVPLG 89
            |.|||.:|:|.:|...:...:..:.|:.::|::.::.| ....::.|.:.:
 Frog    17 LFWKNLLLKWRRKWHTILEWLQNLAFVLVMLLISVMGL-STFVQLEYNSPA-------------- 66

  Fly    90 NRILHENGSLNIPRNF-LCYTPNNPINSAIVGATAIRLRLLGTRA--YDTALHMEQDMVLHNFLA 151
             .:|....:::...|| :.|...:|.:..|:...|..:.:.|.:.  |....::..||. :..:.
 Frog    67 -EVLGRLDAVDRSNNFKVGYVYTSPTSRDIMEKVAKSIIIPGIKVQEYSDEGNLLDDMT-NKAVV 129

  Fly   152 GVQFEDNENVNTNDAGYPLNLNYSLRFPSELRTMQG-------PIIDTWRTSRLFLSYDTSGSRN 209
            ||.|.|..:.:..   ||:|   ::.:|::.....|       ....|:..||.|||...|
 Frog   130 GVTFVDKFSYHIR---YPIN---NIAYPNDYFAFMGFCAPGSQACYPTYYWSRQFLSLQAS---- 184

  Fly   210 RLDNDGGVPVGYIREGFLPIQHALTMSWLALASGVTDTGIPAIHLQRFPYRAYTYDQLLSGLRQL 274
             :|:       .|.|  |...|::   |..:||.||      :.::          ..::..||.
 Frog   185 -IDS-------AIIE--LTSNHSV---WDNMASVVT------VRMK----------STVASFRQY 220

  Fly   275 L---PFVILLSFIYPA--STVTKYVTSEKELQLKEIMKLIGVHNWLHWVAWFVKSYIMLMLVVFL 334
            .   .|:.|:...|.:  ..::.|:|.|:. :::|::|::.:.:...|::|.: .|:..:|::..
 Frog   221 FHIGTFIFLMPMCYVSLMYLLSLYITRERR-EMRELLKMMRLKDLAFWLSWGL-LYLFYILILAN 283

  Fly   335 IMSLIMVKFYASVAVLTFSSWVPVLLFLHTYVVTSVCLCFMLAVLFSKASTASAVAAIFWFLTYI 399
            :|:|:...|     |...||:..::.....|.:..:...|||:.|| ::..|:|:|.  :|:|..
 Frog   284 LMTLVTKAF-----VFVQSSYGIIMFLFVFYGIALMSFTFMLSALF-RSPRATAIAG--FFITLF 340

  Fly   400 PYSFGYYYYERLSLMSK-------LLISLIFSNSALGFGIHVIVMWEGTGEGITWRNMFHPVSTD 457
            ..:.|      |.|:.|       :|:| ||...|...|:...|..|...:|:.:.:|     ..
 Frog   341 LSALG------LVLLRKDFPQALAVLLS-IFPQFAFAVGLTESVHMESDLQGVYFSDM-----AG 393

  Fly   458 DSLTLFYIIMTMSFGSIMFISICLYVEQVFPGEYGVPRRWNFMCHKNYW--RQYVPSL------- 513
            ||..:....::::..||.::.:.||.|:|...::|:.....|....:||  ::..|.|
 Frog   394 DSSHVLSSFISLALDSIFYMGLTLYFEKVLADKHGLKYEPFFFMKSSYWSKKKLSPVLTQTEDSG 458

  Fly   514 --NIVPSFQTI---LHGSAKAKSCRRAREVGIQLFNLQKNYGKLKAVKGISLKMHRNEITVLLGH 573
              ::...|:.:   |||    |...|..:|..:..:..||   ::|::|:.|.::..:||.||||
 Frog   459 ESSMGEFFERVPIDLHG----KEAIRINKVMKKYCDQDKN---IEALRGLDLNIYEGQITALLGH 516

  Fly   574 NGAGKTTTINMITGIVKPTSGTAIVNGYDI--RTHLAKARESLGICPQNNILFKEMSVRDHIIFF 636
            :||||||.:|:::|:...:.|:|.|..|.:  ..||.:.::..|.|||:::.|..::|::::..|
 Frog   517 SGAGKTTLLNILSGLCPASDGSATVYSYKLSDMQHLEEIKKRTGFCPQSDVKFNPLTVKENLTVF 581

  Fly   637 SKLKGIRGTKAVENEVGKYMTMLKLQDKSYVAAKNLSGGMKRKLSLCCALCGNAKVVLCDEPSSG 701
            :|:||| ..|.::::|.|.::.|::.|...|.|.|||||.:|||:|..||.|:.:|:|.|||::|
 Frog   582 AKIKGI-PRKQIKHKVQKVLSDLQMNDIENVEADNLSGGQRRKLTLGIALLGDPQVLLLDEPTAG 645

  Fly   702 IDAAGRRSLWDLLQSEKDGRTILLTTHYMDEADVLGDRIAILSEGKLQCQGTSFYLKKRFGTGYL 766
            :|...|..:|.:|:..|..|..|.:|.:|||||:|.||.|::|.|:|:|.|:|.:||:::|.||.
 Frog   646 LDPCSRHHIWTILKENKADRVTLFSTQFMDEADILADRKAVISNGRLKCVGSSLFLKRKWGIGYH 710

  Fly   767 LVCIMQSGCDVGAVTQLIRKYVPPIKPERVLGTELTYRLPTEYSKKFAELLQDLDEKCAQLQLVG 831
            |...:...|||..:|.:|:::||..|.......||||.||.|....|.:|...||.:... .:|.
 Frog   711 LRMQVSPTCDVELMTSIIKQHVPDAKLTAQNEEELTYTLPFENMDAFPDLFLHLDGQVGN-SIVN 774

  Fly   832 YGLSGATLEDVFMAVNTDKRVQGG-------AEGPPVD------GSIDFKELVFDSKT------- 876
            ||:|..||:|||:.:..:..::.|       ..|.|.|      |..|...|:.||.:
 Frog   775 YGVSMTTLDDVFLKLEGEGEIEKGDYGVFSPDSGAPEDKDCFSAGMEDSLLLMSDSGSATLSGLS 839

  Fly   877 --REK----RRIRRCFMFWQALFLKKFYTTTRNYWLLGIQLVLPIAVMALTILNSRGGRIYYELP 935
              |::    .|:|       .|.||....|.|:..:|....::||.:..:.|      :|::::
 Frog   840 LWRQQVLAIARVR-------LLKLKHDSKTFRSILILLALFIIPIIMTTIVI------KIFHKV- 890

  Fly   936 AMPISINQYSSAYVVLEDNTTDKTSSLADAYSKHLE-HYARRCTLLR----TGDLKFEDY----- 990
                              .|.:.|.||   |.:|.| .:.|..|.|:    ||. ..||:
 Frog   891 ------------------ITWELTPSL---YFQHPEDRFHRYYTDLQIYNNTGS-SIEDFLGALK 933

  Fly   991 ---ILSHDVNHSRRIDFHFLAG-LTVSE----NNFIVWLNNKPLHTAPLTLNLLHNALAIKLLGQ 1047
               |....||....::..|..| :.||:    ..|.:..|.|..:..|:.:|::.||| :.:...
 Frog   934 EQNIAVQVVNGEYDMETTFYRGAIEVSQATKGYGFTIVGNPKAQNALPVLVNIISNAL-LMIFNS 997

  Fly  1048 DASTYVTNEPLP--YSDDTRTLRLNKGQVLGAEISINLSLTMCFITAFYAIPIIRERETRAKLLQ 1110
            .....|.|.|:.  ..:|..::....|        ..|.|....:...:|:..|.:|..:|:...
 Frog   998 TEHIRVWNHPVTEYLVEDFESVTFYSG--------FMLLLFASGLAPHFAMSSIEDRRIKARTQL 1054

  Fly  1111 FLSGVDVCAYWTSH------IVWDYLVFVLSALSSILTIAAFKEIGYITPLDLSRYFYMLLIFGF 1169
            .:||:...|||...      :.|..|..:::.|.|                     |...:||.|
 Frog  1055 RISGIFPSAYWFGQALVDVPLYWILLFLMVAILFS---------------------FNSQVIFSF 1098

  Fly  1170 -PGIMLSYAASGCFSDAATGFTRISIINTLMG------TGLFLMFMTLNFEAFQLKDVAEKLAWY 1227
             |.|:|   .:|.....|.....:.:|:.:.|      .|..:.|:...|....|.||.
 Frog  1099 VPAIIL---ITGVIGYGAAVVLYVYVISFVFGRGKSHHDGWSIFFVISAFIPMILLDVV------ 1154

  Fly  1228 FRLSPHYSLASSTHSIHIGYNIRRGCS-IGGIRKLPKQLRCRNVPICCDIPGYYGWRKPGVLVEI 1291
                       ||:::.|.:.:....| :.||      :||.:|        |:..|.......:
 Frog  1155 -----------STYAVGITFFLLLPASTLSGI------IRCIDV--------YHFDRSTLEDEHL 1194

  Fly  1292 TYMI--MLGSTLFLLIVMHDAKVCNLIAEKLGNCFSKRK----RVEGGTSIENDSVVAEQRVVRE 1350
            .|:.  .|...:|.:|:....:|..:.:.|. |.|.::|    :.|.|...:.:.:...:||...
 Frog  1195 LYLFFPFLHIVIFSVILWVLERVFGMRSLKT-NLFYRKKVQKNQEELGEDTDEEVLAERERVKMS 1258

  Fly  1351 MINSGRKDVPLLV-------YKISK-----RYRSKLAVKAISFHVPHAECFGLLGINGAGKTSTF 1403
            ...:..::.|:::       ||:.|     :...|.|.|.|||.|...|..||||.||||||::.
 Frog  1259 STTNNMEEKPIIIVDSLRKEYKVKKGKSFFKKNKKAATKNISFCVRKGEVLGLLGPNGAGKTTSI 1323

  Fly  1404 KMLAGDEKITSGEAYIDGTN-----ISTHKVYRKIGYCPQFDALFEDLTGRETLNIYCLLRGVQR 1463
            .||||:.:.|:||..:.||:     .|.:.....:|||||.:.|:.:||.::.|.||..::|:::
 Frog  1324 YMLAGEIRPTAGEVLLCGTDPDKSQNSQYDPTGSLGYCPQDNPLWPNLTVKQHLEIYAAVKGLKK 1388

  Fly  1464 RHVTPICWGLAISFGFAKHMDKQTKHYSGGNRRKLSTAISVLGNPSVLYLDEPTSGMDPAARRQL 1528
            :........::.:....:|::|..:..|.|..||:..|||:||||:::.||||::|:||..:::|
 Frog  1389 KDAETAIKRVSEALELKEHLEKAARKLSAGVSRKVCFAISMLGNPNIVLLDEPSTGLDPKGQQRL 1453

  Fly  1529 WQII-GLIRTAGKSIVLTSHSMDECEALCSRLAIMVDGEFKCLGSVQSLKNQFSKGLILKVKVKH 1592
            |:.| ...|...:..:||:|.|:|.||:|.|:||||.|:.:|:||:|.||::|.||.:|::|||:
 Frog  1454 WRAIRSAFRNKDRGAILTTHYMEEAEAVCDRVAIMVSGKLRCIGSIQQLKSKFGKGYLLEIKVKN 1518

  Fly  1593 KKKTFQRVVEDSSSSNDKKSISETDLKFLQMASVMESSQADRILKVNRFISKEIPDAELKEEYNG 1657
                                                |:|.|:|   :..|.:..|.|..::.::.
 Frog  1519 ------------------------------------SNQVDQI---HNEIIQIFPHAARQDRFSS 1544

  Fly  1658 LITYYIP--HSKTLSKIFQLLETNSHKLNIEDYLIMQTRLEEIFLDFASKRDSSD 1710
            |:.|.||  :.::|||.|..||......|||:|...|..|.::|::...:::..|
 Frog  1545 LLVYKIPVENVQSLSKAFLDLEEAKRAYNIEEYSFSQPTLTQVFIELTKEQERED 1599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6052	NP_649002.3	rim_protein	21..>54	CDD:130324	8/28 (29%)
		rim_protein	<149..1709	CDD:130324	441/1680 (26%)
abca8	XP_031749971.1	rim_protein	<225..1601	CDD:130324	414/1546 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D131191at2759
OrthoFinder	1	1.000	-	-		FOG0000051
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010