Protein Alignment CG6052 and abt-2

DIOPT Version :9

• Sequence 1: NP_649002.3
• Gene: CG6052 / 39971
• FlyBaseID: FBgn0036747
• Length: 1725
• Species: Drosophila melanogaster
• Sequence 2: NP_490949.3
• Gene: abt-2 / 171782
• WormBaseID: WBGene00000020
• Length: 2146
• Species: Caenorhabditis elegans
• Alignment Length: 1710
• Identity: 458/1710 - (26%)
• Similarity: 800/1710 - (46%)
• Gaps: 290/1710 - (16%)

  Fly   144 MVLHNFLAGVQFEDNENVNTNDAGYPLNLNYSLRFPSELRTMQGPIIDTWRTSRLFLSYDTSGSR 208
            |..|.:..|:.|    |:::|...:.....|.:|...|:       :|:  |:....|.....||
 Worm   558 MDTHQYFTGIVF----NIDSNATEFDGFTTYKIRHYPEM-------VDS--TTSFMDSKSNPFSR 609

  Fly   209 NR--LDNDGGVPVGYIREGFLPIQHALTMSWLALASGVTDTGIPAIHLQRFPYRAYTYDQLLSGL 271
            ::  :|      :.||..||..:|.::..:.::..:..||..: .::.|:.||.....|.....|
 Worm   610 DKPLID------LKYITFGFSFLQESIDRAIMSELTNQTDANL-GVYAQQEPYPCTVKDTFNVAL 667

  Fly   272 RQLLPFVILLSFIYPASTVTKYVTSEKELQLKEIMKLIGVHNWLHWVAWFVKSYIMLMLVVFLIM 336
              .:|..:|:|||:|::.:.|.:..|||.::||.|:.:|:.:.:|:::|.:.| ::|..:..||:
 Worm   668 --FMPLFLLISFIFPSALLVKNIVYEKEQKIKEQMRAMGLGDAVHFISWGLIS-LVLNFISVLII 729

  Fly   337 SLIMVKFYASVA-VLTFSSWVPVLLFLHTYVVTSVCLCFMLAVLFSKASTASAVAAIFWFLTYIP 400
            |:|     :.|| :..::.:..:|..|..::.:|:.:....:.||:.|:.|:|...:.||:.:||
 Worm   730 SII-----SKVAKIFDYTDYTLLLFVLILFLFSSIAMSIFFSTLFTNANIATAATCVLWFVFFIP 789

  Fly   401 YSFGYYYYERLSLMSKLLISLIFSNSALGFGIHVIVMWEGTG--EGITWRNMF---HPVSTDDSL 460
              |.....:|:|..:...||||...:|:|   |...:.|...  |..||.:::   :|| ...|:
 Worm   790 --FQLLRTDRISSPTFNRISLILPPTAMG---HCFKLLESFNAMERATWSDLWEMNNPV-LGISV 848

  Fly   461 TLFYIIMTMSFGSIMFISICLYVEQVFPGEYGVPRRWNFMCHKNYWRQ--YVPSLNIVPS--FQT 521
            .|..|::.:.  :.:|:.:..|:..|.||::||.:...|.....||..  |...:..|..  |.|
 Worm   849 ELCMIMLVVD--TAVFLILAWYISAVAPGDFGVRQPLWFPFTLKYWAPGLYKNRVEFVDDEHFDT 911

  Fly   522 ILHGSAKAKSCRRAREVGIQLFNLQKNY-GKLKAVKGISLKMHRNEITVLLGHNGAGKTTTINMI 585
            | ..|....|......:.:.:.::.|.| ...||:..::|:::..:||.||||||||||||::::
 Worm   912 I-PNSDSFDSEPTNLTLAVHINSMSKVYENGTKALDCLNLRLYEGQITGLLGHNGAGKTTTMSIL 975

  Fly   586 TGIVKPTSGTAIVNGYDIRTHLAKARESLGICPQNNILFKEMSVRDHIIFFSKLKGIRGTKAVEN 650
            .|:..|:||||.:...||||.|.:.|:.||||||:|:||..::|.:.:..|:.|||:..:: :.:
 Worm   976 CGLYAPSSGTAKIYQRDIRTDLRRVRDVLGICPQHNVLFSHLTVSEQLRLFAALKGVPDSE-LTS 1039

  Fly   651 EVGKYMTMLKLQDKSYVAAKNLSGGMKRKLSLCCALCGNAKVVLCDEPSSGIDAAGRRSLWDLLQ 715
            :|.:.:..:.|.:|:...|..|||||||:|.:..|..|.::.|:.|||::|:|...|:.:|.|||
 Worm  1040 QVDEILASVSLTEKANKLASTLSGGMKRRLCIGIAFIGGSRFVILDEPTAGVDVTARKDIWKLLQ 1104

  Fly   716 SEKDGRTILLTTHYMDEADVLGDRIAILS---------EGK----------LQCQGTSFYLKKR- 760
            ..|:||||||:||:|||||||.|||||||         :||          |.|: .::.||.:
 Worm  1105 RNKEGRTILLSTHHMDEADVLSDRIAILSQDFEKPDLLDGKRLIFQHFYALLVCR-INYTLKSKR 1168

  Fly   761 -FGTGYLLVCIMQSGCDVGAVTQL------IRKYVPPIKPE-RVLGTELTYRL---PTEYSKKFA 814
             |....::...:.:..::..:.|:      :...:||:..| .::|....:.:   .|..:....
 Worm  1169 TFLFQVIIPLFLLALAELFVLLQVSTARPDLMVSMPPLPLETSIMGNHSDFYVNSWDTAENSTAN 1233

  Fly   815 ELLQDL------DEKCA-----------QLQLV-----GY-------GLSGATLEDVFMAVNTDK 850
            ::|..:      ..:||           :.:|:     |:       |:...::::.:...|
 Worm  1234 DILHAMFSSPGTGPRCAKDVPNDLLDTMRRELMFRNRYGFGRNKPAPGVDKDSVDNEYQCQN--- 1295

  Fly   851 RVQGGAE-----------GPPVDGSIDF---------------------KELVFDSKTREKRRIR 883
             :||..:           .|...|..||                     .:.:||...|...:.|
 Worm  1296 -IQGEFDYTEDISNATYNAPIYCGCEDFGWNCTLEDWKWNETNWLRLNTTDRIFDLTGRNLTQFR 1359

  Fly   884 RCFMFWQALFLKKFYTTTRNYWLLGIQL--VLPIAVMALTILNSRGGRIYYELPAMPISINQYSS 946
            ....|.|      ...||..::|.|..|  |...|.....|..|:.|.:.        :|...:.
 Worm  1360 LITRFAQ------LANTTAPFFLGGFSLGHVNQRAQSQADIDTSKRGWLE--------TIKDIAQ 1410

  Fly   947 AYVVLEDNTTDKTSSLADAYSKHLEHYARRCTLLRTGDLKFEDYILSHDVNHSRRIDFHFLAGLT 1011
            :..::..|||    .:..|..|.|:.:|:..|             |:..||       ..|..|.
 Worm  1411 SMRIINLNTT----GIEPATPKVLDPFAQNIT-------------LNQVVN-------DLLQNLD 1451

  Fly  1012 VSENNFIVWLNNKPLHTAPLTLNLLHNAL------AI--KLLGQDASTYVTNEPLPYSDDTRTLR 1068
            |.| |..||.|||.....|:..|:|.|||      ||  :.||.....:..|:.:..:.|...|:
 Worm  1452 VRE-NVKVWFNNKIWPGFPIASNILSNALLRQEDYAIDPEDLGILTMNHPMNKTISQTLDQNALK 1515

  Fly  1069 LNKGQVLGA-EISINLSLTMCFITAFYAIPIIRERETRAKLLQFLSGVDVCAYWTSHIVWDYLVF 1132
            ..  |.|.. .|:| |.|.:..|.|.:.:.::.:|...|..||.:.|:....||.:..::|.:|:
 Worm  1516 FT--QALAVFRITI-LLLVLSMIPAGFTVYLVEDRICEALHLQLVGGLRKVTYWVTSYLYDMVVY 1577

  Fly  1133 VLSALSSILTIAAFKEIGYITPLDLSRYFYMLLIF---GFPGIMLSYAASGCFSDAATGFTRISI 1194
            .|..:..:|....|:...:..  |.:.:|..||:|   |...|:.:|.....||.||..|..|:|
 Worm  1578 TLVIIVIMLIYLCFRVSDFTA--DGATFFAFLLLFFVHGMSTILYAYVFQKAFSVAALSFVLIAI 1640

  Fly  1195 INTLMGTGLFLMFMTLNFEAFQLKDVAEKLAWYFRLSPHYSLASSTHSI----HIGYNIRRGCSI 1255
            .:..:|....|..:.|  |:..::|.:        |.|.:::.|....:    ::|..|.||..|
 Worm  1641 GSYFVGIVCALTVIML--ESLMVQDPS--------LIPAHTVCSIVFLVLPQYNLGIAIFRGLMI 1695

  Fly  1256 GGIRKLPKQ-LRCRNVPICCD---IPGYYGWRKPGVLVEITYMIMLGSTLFLLIVMHDAKVCNLI 1316
            ..:|.:... |:..|.|...:   :|....:.:.|:.:         ..||:.:::  |.:| ||
 Worm  1696 YQVRAIGSNFLQQMNRPDMINQLPLPSLLAFDQMGIHI---------MCLFIHVII--ATIC-LI 1748

  Fly  1317 AEKLGNCFSKRKRVEGGT---------SIENDSVVAEQRVVREMINSGRKDVPLLVYKISKRYRS 1372
            ..::......|||....|         :.:::.||.|::.|..:......:..|:|..::|.|..
 Worm  1749 FSQMDEFGFVRKRERNLTDAMMLREPSTCDDEDVVKERQRVDAIPMDSSDNHALIVRNLAKAYNP 1813

  Fly  1373 K-LAVKAISFHVPHAECFGLLGINGAGKTSTFKMLAGDEKITSGEAYIDGTNISTH-----KVYR 1431
            : ||||.|||.|...|||||||:||||||:||.||....:...|...:..|.|:|.     :.::
 Worm  1814 ELLAVKGISFAVEPGECFGLLGLNGAGKTTTFAMLTAKIRPGHGSIEMQNTRINTGSFSDVRNFQ 1878

  Fly  1432 KIGYCPQFDALFEDLTGRETLNIYCLLRGVQRRHVTPICWGLAISFGFAKHMDKQTKHYSGGNRR 1496
            ::|||||||||...|:.||.|..|..:||:....:..|...|.|:.....:.:.||...||||||
 Worm  1879 QLGYCPQFDALNMKLSTRENLKFYARIRGIVPTQIDSIIDRLLIALHLRPYANTQTSSLSGGNRR 1943

  Fly  1497 KLSTAISVLGNPSVLYLDEPTSGMDPAARRQLWQIIGLIRTAGKSIVLTSHSMDECEALCSRLAI 1561
            |||.|::::..||:::||||::||||.:::.||::|..:..:||::|||||||:||||||:|:||
 Worm  1944 KLSVAVALVSQPSLIFLDEPSAGMDPGSQQFLWKVIERLCKSGKAVVLTSHSMEECEALCTRIAI 2008

  Fly  1562 MVDGEFKCLGSVQSLKNQFSKGLILKVKVKHKKKTFQRVVEDSSSSNDKKSISETDLKFLQMASV 1626
            |..|..:|||..|.||:::.||.:|.:|:             ....|.|           ::|.:
 Worm  2009 MDRGRIRCLGGKQHLKSKYGKGSMLTMKM-------------GKDENAK-----------EIAGI 2049

  Fly  1627 MESSQADRILKVNRFISKEIPDAELKEEYNGLITYYIPH-SKTLSKIFQLLETNSHKLNIEDYLI 1690
            |.|...|              .:.::..:...|..:|.. :.:::::.:::.......:::|:.:
 Worm  2050 MRSKLGD--------------GSRVEAIHCSTIFIHIEQGTASVARVLEIVNQVKKMYDVDDFTL 2100

  Fly  1691 MQTRLEEIFLDFASKRDSSD 1710
            .|:.|:.:|...|...:.|:
 Worm  2101 TQSTLDNVFQSIAESDNLSE 2120

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6052	NP_649002.3	rim_protein	21..>54	CDD:130324
		rim_protein	<149..1709	CDD:130324	455/1702 (27%)
abt-2	NP_490949.3	rim_protein	39..2117	CDD:130324	457/1705 (27%)
		ABC_subfamily_A	929..1134	CDD:213230	92/205 (45%)
		ABC_subfamily_A	1802..2024	CDD:213230	101/221 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53524
OrthoDB	1	1.010	-	-		D131191at2759
OrthoFinder	1	1.000	-	-		FOG0000051
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100045
Panther	1	1.100	-	-	O	PTHR19229
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.930