Protein Alignment CG6052 and abca9

DIOPT Version :9

• Sequence 1: NP_649002.3
• Gene: CG6052 / 39971
• FlyBaseID: FBgn0036747
• Length: 1725
• Species: Drosophila melanogaster
• Sequence 2: XP_031750505.1
• Gene: abca9 / 100496782
• XenbaseID: XB-GENE-6464273
• Length: 1608
• Species: Xenopus tropicalis
• Alignment Length: 1819
• Identity: 466/1819 - (25%)
• Similarity: 805/1819 - (44%)
• Gaps: 378/1819 - (20%)

  Fly    25 LMWKNWILQWNQKMQIVFALVLPVLFLCLILVLRIIVLPEKMDEIRYPTVSISDLNLYMRMVPLG 89
            |.|||.:|:|.:|.......:..:.|:.|:.:..:|       ....|| |.:||:      |.
 Frog    18 LFWKNLLLKWRRKWHSTLEWLQNLAFVFLMFLTIVI-------GFNGPT-SNTDLS------PA- 67

  Fly    90 NRILHENGSLNIPRNF-LCYTPNNPINSAIVGATAIRLRLLGTRAYDTALHMEQDMVLHN-FLAG 152
             |:|   |.|:...|| :.|.....|:..|:...|..:.:...:..:.|...|.....|| .:..
 Frog    68 -RVL---GRLDAFYNFSVGYVRTTSISRDIMEKVAQSIIIPDVKVEEFADEEELMKAFHNTSMVA 128

  Fly   153 VQFEDNENVNTNDAGYPLNLNYSLRF-------PSELRTMQGPIIDTWRTSRLFLSYDTSGSRNR 210
            |.|.|             ..:|.:|:       ||:.....|                      .
 Frog   129 VTFVD-------------KFSYHIRYRMHVMGHPSDYFAFMG----------------------H 158

  Fly   211 LDND--GGVPVGYIREGFLPIQHALTMS----------WLALASGVTDTGIPAIHLQRFPYRAYT 263
            ..||  ..:|..|..||||.:|.::..:          |..:||      |.||.::.   ...|
 Frog   159 CGNDLLYCLPTYYWSEGFLSLQASIDSAIIEVTSNHSVWNNMAS------IVAIKMKS---AQLT 214

  Fly   264 YDQLLSGLRQLLPFVILL-----SFIYPASTVTKYVTSEKELQLKEIMKLIGVHNWLHWVAWFVK 323
            |.:|:    .:..||.::     |.||   .::.|||.|: .::||.::|:.:.:...|::|.:
 Frog   215 YRRLV----HVASFVFVMPMCYVSLIY---LLSLYVTRER-YEMKETLRLMQLKDLAFWLSWGL- 270

  Fly   324 SYIMLMLVVFLIMSLIMVKFYASVAVLTFSSWVPVLLFLHTYVVTSVCLCFMLAVLFSKASTASA 388
            .|...:|:|..:|:||...|     :...||:..::.....|.|..:...|||:.|| ::..|:|
 Frog   271 LYAGYILIVANLMTLITKPF-----IFMTSSYGVIMFLFFLYGVALMSFTFMLSALF-RSPRATA 329

  Fly   389 VAAIFWFLTYIPYSFGYYYYERLSLMSK-------LLISLIFSNSALGFGIHVIVMWEGTGEGIT 446
            ||.  :|:|....:.|      |.|:.|       :|:| ||...|...|:...|..:...||:.
 Frog   330 VAG--FFITLFLSAVG------LVLLRKDFPQALAVLLS-IFPQFAFAVGLLQSVHMDSDLEGVY 385

  Fly   447 WRNMFHPVSTDDSLTLFYIIMTMSFGSIMFISICLYVEQVFPGEYGVPRRWNFMCHKNYWRQYVP 511
            :.::.     .||..:....:::...|:.::.:.||.|:|...::||.....|....:||.:..|
 Frog   386 FSDLM-----GDSSHMLSCFISLVLDSVFYMILTLYFEKVLADKHGVKHEPLFFLKASYWSKEKP 445

  Fly   512 SL--------------NIVPSFQTILHGSAKAKSCRRAREVGIQLFNLQKNYG----KLKAVKGI 558
            |.              :.|......|||           :..|::..::|.:.    ..:|::|:
 Frog   446 SPLMGQTDYSGESSLGDFVEKVPDDLHG-----------KEAIRIHGVKKTFSDKDKSTEALRGL 499

  Fly   559 SLKMHRNEITVLLGHNGAGKTTTINMITGIVKPTSGTAIVNGYDIRT--HLAKARESLGICPQNN 621
            .|.::..:||.||||:||||||.:|:::|:...:.|:|.:..|.:..  ||.:.::.:|.|||.:
 Frog   500 DLNIYEGQITALLGHSGAGKTTLLNILSGMYPASGGSATICNYKLSNMRHLEEIKKRVGFCPQGD 564

  Fly   622 ILFKEMSVRDHIIFFSKLKGIRGTKAVENEVGKYMTMLKLQDKSYVAAKNLSGGMKRKLSLCCAL 686
            |.|..::|:::::.|:.:||| .||.|.::|.|.::.|::.|.....|..||||.:|||:...|:
 Frog   565 IKFDPLTVKENLMVFAMIKGI-PTKQVAHKVQKVLSDLQMNDIENTEAITLSGGQRRKLTFGIAI 628

  Fly   687 CGNAKVVLCDEPSSGIDAAGRRSLWDLLQSEKDGRTILLTTHYMDEADVLGDRIAILSEGKLQCQ 751
            .|:.:|:|.|||::|:|...|..:|.:|:..|..|..|.:|.:|||||:|.||.|::|:|:|:|.
 Frog   629 LGDPQVLLLDEPTAGLDPCSRHHVWTILKENKADRVTLFSTQFMDEADILADRKAVISKGRLKCV 693

  Fly   752 GTSFYLKKRFGTGYLLVCIMQSGCDVGAVTQLIRKYVPPIKPERVLGTELTYRLPTEYSKKFAEL 816
            |:|.:||:::|.||.|...:...|||..:|.:|::.:|..|.......||||.||.|....|.:|
 Frog   694 GSSLFLKRKWGIGYHLRMQVSPSCDVELMTSIIKQRIPSAKLTAQNEEELTYALPFENMDVFPDL 758

  Fly   817 LQDLDEKCAQLQLVGYGLSGATLEDVFMAVNTDKRVQGGAEGPPVDGSIDFKELVFDSKTREKRR 881
            ...||.:... .:|.||:|..||:|||:.:..:..::.|          |:.....:|:|.|.|.
 Frog   759 FSHLDGQVGN-SIVSYGVSMTTLDDVFLKLEGEGEIESG----------DYDVFNPESRTAEDRY 812

  Fly   882 IRRCFMFWQALFLKKFYTTTRNYWLLGIQLVLPIA-------------------VMALTILNS-- 925
            .....|....|.:......|.:.|.|..|.||.:|                   ::.|.||.|
 Frog   813 DISAEMEESLLLMSDSGNVTLSGWELWRQQVLAVARIRFLKLRHDTKSLRSILLLLVLFILASIL 877

  Fly   926 ---------------RGGRIYYELPAMPISINQYSSAYVVLEDNTTDKTSSLADAYSKHLEHYAR 975
                           ....:|::.|..  .:|:|.:. :::.:||   .||:.|.
 Frog   878 SIIMAHISNKFISWELTPSLYFQSPGS--RLNKYYTD-LLIHNNT---GSSIDDF---------- 926

  Fly   976 RCTLLRTGDLKFEDYILSHDVNHSRRID-FHFLAGLTVSE----NNFIVWLNNKPLHTAPLTLNL 1035
                  .|.:| |..|.....|....:| ..:...:.||:    .||.:..|.|..:..|:.||:
 Frog   927 ------IGAVK-EQNIAVQVANGKYDMDTIKYRGAIEVSQAEKGYNFTIVANPKAHNALPVLLNI 984

  Fly  1036 LHNALAIKLLGQDASTYVTNEPLPYSDDTRTLRLNKGQVLGAEISINLSLTMCF---ITAFYAIP 1097
            :.||| :|:........|.|.|:...:          ..:..:..|::...|.|   ::...|:.
 Frog   985 ISNAL-LKVFKVSEHVRVWNHPITMDE----------MDIHHKTYISIMFFMIFASGLSPHIAMS 1038

  Fly  1098 IIRERETRAKLLQFLSGVDVCAYWTSHIVWDY-----LVFVLSALSSILTIAAFKEIGYITPLDL 1157
            ...:....|:....|:|:...|||....:.|.     |:|:::|:     :.||
 Frog  1039 STEDNRINARTQLRLAGLFPSAYWFGQALVDVILYWSLLFLMTAI-----LFAF----------- 1087

  Fly  1158 SRYFYMLLIFGFPGIMLSYAASGCFSDAATGFTRISIINTLMGTGLF------LMFMTLNFEAFQ 1216
            :.|.|.||.|....:|:    :|.|.........:.:|:.:.|.|..      |.|:.:.|  |.
 Frog  1088 NNYSYFLLNFITAMVMI----AGMFGYGMAVILYVYVISFIFGKGKIHRDSWSLFFVIITF--FP 1146

  Fly  1217 LKDVAEKLAWY------FRLSPHYSLASSTHSIHIGYNIRRGCSIGGIRKLPKQLRCRNVPICC- 1274
            ..:......|:      |.::..|.:...|..:..                  .....|..:.|
 Frog  1147 ASNEISIFPWFYIYLFIFPVTTLYGIMDYTEDLQF------------------LQEADNFILPCT 1193

  Fly  1275 ---DIPGYYG--WRKPGVLVEITYMIMLGSTLFLLIVMHDAKVCNLIAEKLGN-----CFSKRKR 1329
               .|..::|  |     .:|..:.:...:|..|..:...........|:|||     ..::::|
 Frog  1194 PYLHIIIFFGLLW-----FLEWKFGLRSLTTDPLFRISRRNMTVKKNPEELGNDVDEDVLAEKER 1253

  Fly  1330 VEGGTSIENDSVVAEQRVVREMINSGRKDVPLLVYKISKR-----YRSKLAVKAISFHVPHAECF 1389
            |:...::.|   |.|:.|:  :::|.||:     ||:.||     ...|.|.|.|||.|...|..
 Frog  1254 VKNAATVAN---VEEKPVI--IVDSLRKE-----YKVKKRGSFFKKNRKAATKNISFCVRKGEVL 1308

  Fly  1390 GLLGINGAGKTSTFKMLAGDEKITSGEAYIDGTNISTHKVYRKIGYCPQFDALFEDLTGRETLNI 1454
            ||||.||||||::..||||:.|.|:||..:.|.:.:....:  :|||||.:.|:.:||.:|.|.|
 Frog  1309 GLLGPNGAGKTTSMYMLAGEVKPTAGEVVLCGNDPAESTGF--LGYCPQDNPLWPNLTVKEHLEI 1371

  Fly  1455 YCLLRGVQRRHVTPICWGLAISFGFAKHMDKQTKHYSGGNRRKLSTAISVLGNPSVLYLDEPTSG 1519
            |..::|:::.........:|.:....:||.|:::..|.|..||:..|||::|||:::.||||::|
 Frog  1372 YAAVKGMKKEDAYIAINRVAAALELKEHMGKESRKLSLGESRKVCFAISMIGNPNIVLLDEPSTG 1436

  Fly  1520 MDPAARRQLWQII-GLIRTAGKSIVLTSHSMDECEALCSRLAIMVDGEFKCLGSVQSLKNQFSKG 1583
            :||.|:::||:.| ...:...:..:||:|.|:|.||:|.|:||||.|:.:|:||:|.||::|.||
 Frog  1437 LDPKAQQRLWRAIRAAFKNKDRGAILTTHYMEEAEAVCDRVAIMVSGKLRCIGSIQQLKSKFGKG 1501

  Fly  1584 LILKVKVKHKKKTFQRVVEDSSSSNDKKSISETDLKFLQMASVMESSQADRILKVNRFISKEIPD 1648
            .:|::|||                                    |:.|.|:|   :..|.:..|.
 Frog  1502 YLLEIKVK------------------------------------ETHQVDQI---HNEIIRIFPH 1527

  Fly  1649 AELKEEYNGLITYYIP--HSKTLSKIFQLLETNSHKLNIEDYLIMQTRLEEIFLDFASKRDSSD 1710
            |..::.::.|:.|.||  :.::||:.|.|||......|||:|...|:.||::|::.|.:::..|
 Frog  1528 AARQDRFSSLLVYKIPMDNVQSLSQAFLLLEEAKRAYNIEEYSFSQSTLEQVFIELAKEQEKED 1591

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6052	NP_649002.3	rim_protein	21..>54	CDD:130324	8/28 (29%)
		rim_protein	<149..1709	CDD:130324	435/1690 (26%)
abca9	XP_031750505.1	rim_protein	<170..1595	CDD:130324	425/1613 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D131191at2759
OrthoFinder	1	1.000	-	-		FOG0000051
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010