Protein Alignment Crtc and crtc3

DIOPT Version :9

• Sequence 1: NP_001261997.1
• Gene: Crtc / 39970
• FlyBaseID: FBgn0036746
• Length: 889
• Species: Drosophila melanogaster
• Sequence 2: XP_005166549.1
• Gene: crtc3 / 570024
• ZFINID: ZDB-GENE-070712-2
• Length: 667
• Species: Danio rerio
• Alignment Length: 882
• Identity: 200/882 - (22%)
• Similarity: 286/882 - (32%)
• Gaps: 314/882 - (35%)

  Fly     2 ANPRKFSEKIALQKQKQAEGTAEFERIMKEVYATKRDEPPANQKILDGLVGGQEVSQSSPGAGNG 66
            :|||||||||||..|||||.|..||::|.::..::              |..|::.|........
Zfish    10 SNPRKFSEKIALHNQKQAEETRAFEQLMTDLTVSR--------------VQFQKIQQLRLSQNRA 60

  Fly    67 TGGGGSGSGSGASGG------GASPDGLGGGGGS---PTAYRESRGRSVGVGPMRRPSE---RKQ 119
            ...|||.......|.      |..|.||....|:   ....|..|.|:....|.|||.:   |:.
Zfish    61 QYYGGSLPNVNQIGNASTDFQGTFPSGLDSVRGTRHHGLVERVHRDRNRINSPHRRPIDKHGRQA 125

  Fly   120 DRSPYGSSSTQQTLDNGQLNPHLLGPPTAE--------SLWRRSSSDSALHQSALVAGFNSDVNS 176
            :.||||:.......||......|  |.|.|        |...|::||||||.||:..   :..:.
Zfish   126 ESSPYGTMYLSPPPDNSWRREQL--PWTEEKRPGFRLISQLNRTNSDSALHTSAMNP---NPQDP 185

  Fly   177 MGANYQQQQHQQQQQPGQPRSHS-------------------PHH----GINRTMSPQ---AQRR 215
            .|.|       ||...|.|:.::                   |:.    |:|:.|..|   |::.
Zfish   186 FGMN-------QQMGRGPPQRNASMNEAEVDSSGDVFSFPAVPNEENLLGVNKPMPKQLWEAKKV 243

  Fly   216 KSPLLQPHQLQLQQLQ-----QQQQQMQH-QHQLHQQLQMQQLQQHQQQHQQQQQQQNTPYNNAK 274
            :|...:|...::..:.     :|...:.| |..|:....:..|                  :|..
Zfish   244 QSLSSRPKSCEVPGINIFPSPEQNAGLSHYQGTLNTGGSLPDL------------------SNLH 290

  Fly   275 FTNPVFRPLQ-DQVNFAN------TGSLPDLTALQNYGPQQQQQQSQQQPSQQ----QQQLQQTL 328
            |.:|:..||. |:..:.|      ||:||........|..|....|...||.|    ..||..:|
Zfish   291 FPSPLPTPLDPDEAGYPNLSGGSSTGNLPAAMMHLGIGNSQGLSSSLSNPSIQASLTNSQLHSSL 355

  Fly   329 SPVMSPHNHRRERDQSPSPFSPAGGGGGAGP---GSPYQQQQHSPTGNTQQQQQQHQQPSNSPHL 390
            |   :|..|...|..|.|  :|...|..:.|   .:|......||.|:.::...:...|:.||.|
Zfish   356 S---NPSLHSSLRLSSMS--NPPPTGMASSPRRRPAPISPLTLSPGGDQRRSLSKQLSPTMSPSL 415

  Fly   391 SFTNLATTQAAVTTFNPLPTLGPHNATDYRQPPNPPSPRSSPGLLSSVSATDLHSSAPASPIRQQ 455
            |    ..||......:.||...|.....|:|...|..|:|...:..|       |..|.  ::|:
Zfish   416 S----PITQGVALDTSNLPMEPPPPYPLYQQSQQPQPPQSHQAIQQS-------SQHPG--VQQR 467

  Fly   456 QQAHQQQQQQQQAQQQQQQ----FDNSYNSLNTSFHNQFEIFSLGDSNSSPEQQGFANN-FVALD 515
            ....||||||||.|||..|    ..|.....|:|.||              ...||.|: |:...
Zfish   468 AAGGQQQQQQQQQQQQHHQPVSPLQNIQLDFNSSAHN--------------SMAGFFNDPFMEQQ 518

  Fly   516 FDDLSGGGGGGPSGGGGSNGGGLTNGYNKPEMLDFSELSGSPEASGNNNHMRRGVSNLNNNGLSN 580
            |           ||..........:.||   ||:
Zfish   519 F-----------SGRQSKCSAYQQDQYN---MLE------------------------------- 538

  Fly   581 GVVGSTHNGSTNLNGAGNNNSSSGGGTAQDPLGITTSPVPSPLGCPSSPLPIPIPMSAQSSPQQQ 645
                             |..||..||.  ||        .|.|.|..:.|     |....|....
Zfish   539 -----------------NVMSSMAGGF--DP--------SSNLYCSQAAL-----MGLGGSHGNL 571

  Fly   646 HHHHQQQQQQHHQQQHHQQQQLSLSLHHSPHHSPMHSPHHGNSPLSSSSPVSHNACSNSNVVMNH 710
            |.|.|.:|.                                         :.::.|....
Zfish   572 HDHFQMRQN-----------------------------------------MLYSNCGGGG----- 590

  Fly   711 QQQQQQHHHQQHHHQGSSQSHTPTTANIPSIIFSDYSSNADYTREIFDSL--------------- 760
                                     ..:|:||.:| .||...:::|...|
Zfish   591 -------------------------GGVPNIILTD-DSNPSLSKDISSVLSAVPECLDSEGVFPL 629

  Fly   761 --DLDLGQMDVAGLQMLSDQNPIMIADPNIEDSFRRD 795
              :|.:..:.:.||.||||.: :::.||::|||||.|
Zfish   630 EDELRIEPLSLDGLSMLSDPD-MVLPDPSVEDSFRSD 665

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Crtc	NP_001261997.1	TORC_N	3..61	CDD:289639	23/57 (40%)
		TORC_C	739..795	CDD:289641	22/72 (31%)
crtc3	XP_005166549.1	TORC_N	11..68	CDD:289639	26/70 (37%)
		TORC_M	166..330	CDD:289640	40/191 (21%)
		TORC_C	594..667	CDD:289641	23/74 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595715
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28MKB
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	101	1.000	Inparanoid score	I4976
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001294
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13589
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1320
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.980