Protein Alignment Crtc and Crtc3

DIOPT Version :9

• Sequence 1: NP_001261997.1
• Gene: Crtc / 39970
• FlyBaseID: FBgn0036746
• Length: 889
• Species: Drosophila melanogaster
• Sequence 2: XP_006229524.1
• Gene: Crtc3 / 365297
• RGDID: 1309666
• Length: 618
• Species: Rattus norvegicus
• Alignment Length: 867
• Identity: 183/867 - (21%)
• Similarity: 257/867 - (29%)
• Gaps: 333/867 - (38%)

  Fly     2 ANPRKFSEKIALQKQKQAEGTAEFERIMKEVYATKRDEPPANQKILDGLVGGQ--EVSQSSPGAG 64
            ||||||||||||..|:|||.|..||::|.::..::.......|..|....||.  .|||..
  Rat    10 ANPRKFSEKIALHTQRQAEETRAFEQLMTDLTLSRVQFQRLQQLRLTQHHGGSLPNVSQLR---- 70

  Fly    65 NGTGGGGSGSGSGASGGGASP---------DGLGGGGGSPTAYRESRGRSVGVGPMRRPS----E 116
                             |::|         |.:.|........|.:|.|   ..|:.|.|    .
  Rat    71 -----------------GSAPELQPSLHHADNVRGTRHHGLVERPARNR---FHPLHRRSGDKPG 115

  Fly   117 RKQDRSPYGSSSTQQTLDNGQLNPHLLGPPTAE---------SLWRRSSSDSALHQSALVAGFNS 172
            |:.|.:.:.:|.:.|.||.......   ||..|         |...|::||||||.|||
  Rat   116 RQFDGNAFAASYSSQPLDESWPRQQ---PPWKEEKHPGFRLTSALNRTNSDSALHTSAL------ 171

  Fly   173 DVNSMGANYQQQQHQQQQQP----GQPRSHSPHHGI--------NRTMSPQAQRRKSPLLQPHQL 225
                         ..:.|.|    ||....:|:.|.        .....|...:.::.|..|..|
  Rat   172 -------------STKPQDPYGGGGQSAWPAPYMGFCDGENDGRGEAAFPGLLKEENLLNVPKPL 223

  Fly   226 QLQQLQQQQQQMQHQHQLHQQLQMQQLQQHQQQ----------HQQQQQQQNTPYNNAKFTNPVF 280
                          ..||.:..::|.|....:.          |..|              |...
  Rat   224 --------------PKQLWETKEIQSLSGRPRSCDVGGGSAFPHNGQ--------------NTGL 260

  Fly   281 RPLQDQVNFANTGSLPDLTALQNYGPQQQQQQSQQQPSQQQQQLQQTLSPVMSPHNHRRERDQSP 345
            .|....:|  ..|||||||.|....|                 |..:|             |.|.
  Rat   261 SPFLGTLN--TGGSLPDLTNLHYSAP-----------------LPASL-------------DTSD 293

  Fly   346 SPFSPAGGGGGAGPGSPYQQQQHSPTGNTQQQQQQHQQPSNSPHLSFTNLATTQAAVTTFNPLPT 410
            ..|.....|...|                       ..|:...||...|.:..|
  Rat   294 HLFGSMSVGNSVG-----------------------NLPAAMTHLGIRNSSGLQ----------- 324

  Fly   411 LGPHNATDYRQPPNPPSPRSSPGLLSSVSATDLHSSAPASPIRQQQQAHQQQQQQQQAQQQQQQF 475
                            |.||:|.:.::::...|.||..:.|                    |...
  Rat   325 ----------------SSRSNPSIQATLNKIALSSSLNSHP--------------------QPSV 353

  Fly   476 DNSYNSLNTSFHNQFEIFSLGDSNSSPEQQGFANNFVALDFDDLSGGGGGGPSGGGGSNGGGLTN 540
            .|:     ::.|....:|||    |:|          :|...:||     |||.........||
  Rat   354 ANA-----SALHPSLRLFSL----SNP----------SLSTTNLS-----GPSRRRQPPVSPLT- 393

  Fly   541 GYNKPEMLDFSELSGSPEASGNNNHMRRGVSNLNNNGLSNGVVGSTHNGSTNLNGAGNNNSSSGG 605
                        ||..|||....|......|.||....|..|.
  Rat   394 ------------LSPGPEAHQGFNRQLSATSPLNPYPASQMVT---------------------- 424

  Fly   606 GTAQDPLGITTSPVPSPLGCPSSPLPIPIPMSAQSSPQ---QQHHHHQQQQQQHHQQQHHQQQQL 667
             :.|.||....:...:.:   |.|.|.|.|   |..||   ||.|.|:...||........|...
  Rat   425 -SEQSPLSFLPTDAQAQV---SPPPPYPTP---QELPQPLLQQPHAHEPPAQQPQAAPSLSQSDF 482

  Fly   668 SLSLHHSP-----------HHSPMH-SPHHGNS-PLSSSSPVSHNACSNSNVVMNHQQQQQQHHH 719
            .|......           ...||. ||..... ||               |..:|::.|...|.
  Rat   483 QLLTAQGSSLTNFFRDVGFDQQPMRPSPAFPQQVPL---------------VQQSHREPQDSFHL 532

  Fly   720 QQHHHQG-SSQSHTPTTANIPSIIFSDYSSNADYTREIFDSLDLD----------LGQMDVAGLQ 773
            :.:.:.. .|..:|..|.:..:.:|...|.......|:  |||:|          :..:.:.||.
  Rat   533 RPNPYSNCGSFPNTILTEDTNTSLFKGLSGGLSGMPEV--SLDMDTPFPLEEELQIEPLSLDGLN 595

  Fly   774 MLSDQNPIMIADPNIEDSFRRD 795
            ||||.: :.:.||::|::||.|
  Rat   596 MLSDSS-MGLLDPSVEETFRAD 616

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Crtc	NP_001261997.1	TORC_N	3..61	CDD:289639	26/59 (44%)
		TORC_C	739..795	CDD:289641	18/65 (28%)
Crtc3	XP_006229524.1	TORC_N	11..64	CDD:289639	23/52 (44%)
		TORC_M	159..320	CDD:289640	48/262 (18%)
		TORC_C	544..618	CDD:289641	21/76 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166353578
Domainoid	1	1.000	51	1.000	Domainoid score	I11278
eggNOG	1	0.900	-	-		E1_28MKB
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	91	1.000	Inparanoid score	I5012
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001294
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13589
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1320
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.980