Protein Alignment Crtc and crtc2

DIOPT Version :9

• Sequence 1: NP_001261997.1
• Gene: Crtc / 39970
• FlyBaseID: FBgn0036746
• Length: 889
• Species: Drosophila melanogaster
• Sequence 2: XP_031746644.1
• Gene: crtc2 / 101733698
• XenbaseID: XB-GENE-22068304
• Length: 845
• Species: Xenopus tropicalis
• Alignment Length: 995
• Identity: 227/995 - (22%)
• Similarity: 309/995 - (31%)
• Gaps: 369/995 - (37%)

  Fly     2 ANPRKFSEKIALQKQKQAEGTAEFERIMKEVYATKRDEPPANQKILDGLVGGQEVSQSSPGAGNG 66
            :||||||||||||:|:|||.||.||.:|.::.:|:...    ||:....:.|.....|.|.. |.
 Frog    16 SNPRKFSEKIALQRQRQAEETAAFEEVMMDIGSTRLQV----QKLRMAHMRGPYYGGSLPNV-NQ 75

  Fly    67 TGGGGSGS------GSGASGGGASPDGLGGGGGSPTAYRESRGRSVGVGPMRRPSERKQDRSPYG 125
            .|.|||..      ....|.......||        ..|..|.....:.|:|| ..|:.|.|||.
 Frog    76 IGSGGSAEFQCPPHSPLESSRSTRHHGL--------VERVQRDPRRMMSPLRR-YMRQLDSSPYN 131

  Fly   126 SS--STQQ-------------TLDNGQLNPHLLGPPTAESLWRRSSSDSALHQSALVAGFNSDVN 175
            :|  |.||             ..|.||    |...|||   ..|::||||||.|.:
 Frog   132 ASYLSPQQEPSWRRNMPWGNYPSDTGQ----LFRLPTA---LNRTNSDSALHTSVM--------- 180

  Fly   176 SMGANYQQQQHQQQQQPGQPRSHSPHHGINRTMSPQAQRRKSPLLQPHQLQLQQLQQQQQQMQHQ 240
                              .|.|..|:........|   .|::..|.|.....:.|......:...
 Frog   181 ------------------NPSSQDPYGAAQGMALP---NRRTAFLFPAPAIEEDLHSDSSHLLSP 224

  Fly   241 HQLHQQLQMQQLQQHQQQHQQQQQQQNTPYNN--AKFTNPV-FRPLQDQVNFANTGSLPDLTALQ 302
            ....:.|          ....:.:....|..|  .....|. ..|:...:|  :.|||||||.|
 Frog   225 CDAKRML----------MSSSRPKSCEVPGINICPSVDEPTSIPPVPSVLN--SGGSLPDLTNL- 276

  Fly   303 NYGPQQQQQQSQQQPSQQQQQLQQTLSPVMSPHNHRRERDQSPSPFSPAGGGGGAG--------- 358
                                   ...||:.:|      .|...|.||...||...|
 Frog   277 -----------------------HLPSPLPTP------LDLDESGFSSLSGGSSTGNLANTMTHL 312

  Fly   359 -------------PG-SPYQQQQ-------HSPTGNTQQQ-----------------QQQHQQPS 385
                         || ||...|.       .|...|...|                 |..:..||
 Frog   313 GISRMGLAPEYEIPGYSPSSVQNSLSRSSLQSSLSNPNLQASLSNPSLQASLSNPSLQTSYSNPS 377

  Fly   386 NSPHLSFTNLA-----TTQAAVTTFN-----------PLPTLGPHNATDYRQPPNPP-------- 426
            ....||..:|.     ::|:..:.::           |:||  |.|.:..|:.|..|
 Frog   378 LQSSLSSQSLTSSLSNSSQSLPSAYSTPSSPSSSFPPPVPT--PMNTSPRRRVPLSPLTLPLGGD 440

  Fly   427 ---------SPRSSPGLLSSVS-----------------------ATDLH-SSAPASPIRQQQQ- 457
                     ||..|| .|||::                       |:.|| |..|..|:.|.||
 Frog   441 SRRAHQKQFSPTMSP-TLSSITQGVPLDTSKFPGDQRLPPYHFSHASLLHPSQQPQQPLHQSQQP 504

  Fly   458 AHQQQQ--QQQQAQQQQQQFDNSYNSLNTSFHNQFEIFSLGDSNSSPEQQGFANNFVALDFDDLS 520
            .|||.|  .||...||.||          ..|.|.:         .|.||........
 Frog   505 LHQQLQPPSQQPLHQQLQQ----------PLHQQLQ---------PPSQQPLHQQLQP------- 543

  Fly   521 GGGGGGPSGGGGSNGGGLTNGYNKPEMLDFSELSGSP------EASGNNNHMRRGVSNLNNNGLS 579
                  ||              .:|.......||..|      ..|....|..:..|:.......
 Frog   544 ------PS--------------QQPLHQQLQPLSQQPLHQQLQPPSQQPLHRSQQPSHQAQQSSQ 588

  Fly   580 NGVVGSTHNGSTNLNGAGNNNSSSGGGTAQDPLGITTSPVPSPLGCPSSPLPIPIPMSAQSS--- 641
            ..::   |.....|:.:.:|..:| ...:|.||..:.|.|..     |.|...|.|.|.:.|
 Frog   589 QPLL---HQSQQPLHQSPHNLQNS-VHQSQQPLPHSQSSVNQ-----SQPAATPSPQSQRQSQAP 644

  Fly   642 --PQQQHHHHQQQQQQHHQQQHHQQQQLSLSLHHSPHHSPMHSPHHGNSPLSSSSPVS---HNA- 700
              |.|| ...:|.||..:|..||.||.|.               .:...||..:.|.|   |:|
 Frog   645 MNPSQQ-QSVKQSQQMSNQSSHHSQQPLQ---------------QYSQKPLQQAPPGSQQFHSAS 693

  Fly   701 ------CSNSNVVMNHQQ--------QQQQHHHQQHHHQG--------SSQSH------TPTTAN 737
                  |..::....:||        ..:|.:..:.|..|        |.:.|      |||...
 Frog   694 QHFPAPCQQNSGGQPYQQLFEHYSLGSLEQFNMLEGHSGGFGLTGGFFSGEQHGGTLNGTPTLNK 758

  Fly   738 -----------IPSIIFSDYSSNADYTREIFDSL----------------DLDLGQMDVAGLQML 775
                       ||.||.:...|...:::||..:|                ||::..:.:.||.||
 Frog   759 QNLNNCSRHEPIPDIILTAVDSPPGFSKEITSALSCVPGFEVDQSLGLEEDLNIEPLTLDGLNML 823

  Fly   776 SDQNPIMIADPNIEDSFRRD 795
            ||.. .::.||.:|||||.|
 Frog   824 SDPY-ALLTDPMVEDSFRSD 842

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Crtc	NP_001261997.1	TORC_N	3..61	CDD:289639	26/57 (46%)
		TORC_C	739..795	CDD:289641	22/71 (31%)
crtc2	XP_031746644.1	TORC_N	17..71	CDD:403936	26/57 (46%)
		TORC_M	168..315	CDD:403937	40/218 (18%)
		PRK10263	<610..>704	CDD:236669	30/114 (26%)
		TORC_C	771..844	CDD:403938	23/73 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	50	1.000	Domainoid score	I11470
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	133	1.000	Inparanoid score	I4476
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001294
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1320
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.050