Protein Alignment CG7497 and Ptgdr

DIOPT Version :10

• Sequence 1: NP_648999.2
• Gene: CG7497 / 39966
• FlyBaseID: FBgn0036742
• Length: 412
• Species: Drosophila melanogaster
• Sequence 2: NP_071577.2
• Gene: Ptgdr / 63889
• RGDID: 619707
• Length: 357
• Species: Rattus norvegicus
• Alignment Length: 410
• Identity: 97/410 - (23%)
• Similarity: 148/410 - (36%)
• Gaps: 140/410 - (34%)

  Fly    34 IGVIIMVLGVFGNSLALFILARKKLNK----------NSKYTLMLRCLATNNLVALLG--MLTTT 86
            :|.::...|:.||.|||.:|||..|..          :..|.|:.....|:    |||  :::..
  Rat    21 MGGVLFSAGLLGNLLALVLLARSGLGSCRPGPLHPPPSVFYVLVCGLTVTD----LLGKCLISPM 81

  Fly    87 LLKMYLS----KEVLQSFIRVDCVGLV-VWRFFGLSSGCIAAVMAAERWMALARPFIYHKHITYE 146
            :|..|..    ||:|.:.....|.... :..||||:|......||.|.|::|..||.|.:|||
  Rat    82 VLAAYAQNRSLKELLPASGNQLCEAFAFLMSFFGLASTLQLLAMALECWLSLGHPFFYQRHIT-- 144

  Fly   147 LIRKSINSILMIAVVITF------LPFVGFGAYIDESNPDQLKCIRYRDAPGVW------NKT-- 197
                :...:|:..|...|      |||.|||           |.::|  .||.|      :|.
  Rat   145 ----ARRGVLVAPVAGAFSLAFCALPFAGFG-----------KFVQY--CPGTWCFIQMIHKKRS 192

  Fly   198 -----YAVLFMVFGTLLCIVIVACNLFVAHTLLCVIGRSRTAKRHMHYDLVSRDKNSAISIDPES 257
                 ::||:.....||.:..|.|||.....|..:..|    :|| |....|||:
  Rat   193 FSVIGFSVLYSSLMALLVLATVVCNLGAMSNLYAMHRR----QRH-HPRRCSRDR---------- 242

  Fly   258 SSGTTLYQTQLSTGSGNSHRSVQPARQYRHSVSVTMAATDSSPVEIKFAKLMAFLSISFVICWMP 322
                      ..:||...|.|..|..:..|.|                  |:|..::.|.:|.:|
  Rat   243 ----------AQSGSDYRHGSPNPLEELDHFV------------------LLALTTVLFTMCSLP 279

  Fly   323 QMI-----AIPLAIAPNRVPASNKFFIIADVLTALHFTS-----DPYVYVLSRSKSI-------- 369
            .:.     |..|.   :|....      ::.|.||.|.|     ||:::::.|:...
  Rat   280 LIYRAYYGAFKLV---DRADGD------SEDLQALRFLSVISIVDPWIFIIFRTSVFRMLFHKTF 335

  Fly   370 -------NWSLLGCIKRWRS 382
                   ||    |...|::
  Rat   336 TRPLIYRNW----CSHSWQT 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7497	NP_648999.2	7tm_GPCRs	34..365	CDD:475119	92/376 (24%)
		TM helix 1	34..55	CDD:410628	8/20 (40%)
		TM helix 2	68..87	CDD:410628	4/20 (20%)
		TM helix 3	99..127	CDD:410628	7/28 (25%)
		TM helix 4	150..166	CDD:410628	3/21 (14%)
		TM helix 5	195..218	CDD:410628	7/29 (24%)
		TM helix 6	306..328	CDD:410628	6/26 (23%)
		TM helix 7	340..365	CDD:410628	7/29 (24%)
Ptgdr	NP_071577.2	7tm_GPCRs	16..331	CDD:475119	93/384 (24%)
		TM helix 1	18..42	CDD:410628	8/20 (40%)
		TM helix 2	61..83	CDD:410628	6/25 (24%)
		TM helix 3	105..127	CDD:410628	6/21 (29%)
		TM helix 4	150..166	CDD:410628	3/15 (20%)
		TM helix 5	195..218	CDD:410628	6/22 (27%)
		TM helix 6	263..285	CDD:410628	6/39 (15%)
		TM helix 7	298..323	CDD:410628	7/30 (23%)