DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG7497 and PTGIR

DIOPT Version :9

Sequence 1:NP_001287100.1 Gene:CG7497 / 39966 FlyBaseID:FBgn0036742 Length:412 Species:Drosophila melanogaster
Sequence 2:NP_000951.1 Gene:PTGIR / 5739 HGNCID:9602 Length:386 Species:Homo sapiens


Alignment Length:370 Identity:82/370 - (22%)
Similarity:137/370 - (37%) Gaps:111/370 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    37 IIMVLGVFGNSLALFILARKKLNKNSKYTLMLRCLATNNLVALLGMLTTTLLKMYLSKEVLQSFI 101
            ::.|.||.||.|||.||:.::..:.|.:.:::..||..:|:.          ..:||..|..::.
Human    22 LMFVAGVVGNGLALGILSARRPARPSAFAVLVTGLAATDLLG----------TSFLSPAVFVAYA 76

  Fly   102 R-VDCVGLV------------VWRFFGLSSGCIAAVMAAERWMALARPFIYHKHITYELIRKSIN 153
            | ...:||.            ...||||:|..|...||.||.:||:.|::|.:.......|.::.
Human    77 RNSSLLGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLALSHPYLYAQLDGPRCARLALP 141

  Fly   154 SILMIAVVITFLPFVGFGAYIDESNPDQLKCIRYRDAPGVW-----------NKTYAVLFMVFGT 207
            :|....|:...||.:|.|.:       |..|      ||.|           ...:::.:.....
Human   142 AIYAFCVLFCALPLLGLGQH-------QQYC------PGSWCFLRMRWAQPGGAAFSLAYAGLVA 193

  Fly   208 LLCIVIVACNLFVAHTL-LCVIGRSRTAKRHMHYDLVSRDKNSAISIDPESSSGTTLYQTQLSTG 271
            ||...|..||..|  || ||.:.|.:  |||..            |:.|...:|..         
Human   194 LLVAAIFLCNGSV--TLSLCRMYRQQ--KRHQG------------SLGPRPRTGED--------- 233

  Fly   272 SGNSHRSVQPARQYRHSVSVTMAATDSSPVEIKFAKLMAFLSISFVICWMPQMI-AIPLAIAPNR 335
                                          |:....|:|.:::...:|.:|..| ....|:||: 
Human   234 ------------------------------EVDHLILLALMTVVMAVCSLPLTIRCFTQAVAPD- 267

  Fly   336 VPASNKFFIIADVLTALHFTSDPYVYVLSRSKSINWSLLGCIKRW 380
             .:|....::|....|.:...||:|::|.|.     ::...:|.|
Human   268 -SSSEMGDLLAFRFYAFNPILDPWVFILFRK-----AVFQRLKLW 306

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7497NP_001287100.1 7tm_4 36..>221 CDD:304433 51/207 (25%)
PTGIRNP_000951.1 7tm_GPCRs 14..304 CDD:333717 80/366 (22%)
TM helix 1 16..40 CDD:320095 10/17 (59%)
TM helix 2 50..72 CDD:320095 5/31 (16%)
TM helix 3 93..115 CDD:320095 7/21 (33%)
TM helix 4 138..154 CDD:320095 2/15 (13%)
TM helix 5 181..204 CDD:320095 4/22 (18%)
TM helix 6 235..260 CDD:320095 5/24 (21%)
TM helix 7 271..296 CDD:320095 6/24 (25%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 52 1.000 Domainoid score I11441
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 71 1.000 Inparanoid score I5311
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D412827at33208
OrthoFinder 1 1.000 - - FOG0000857
OrthoInspector 1 1.000 - - oto91840
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - LDO PTHR11866
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
77.070

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