DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7497 and ptger2b

DIOPT Version :9

Sequence 1:	NP_001287100.1	Gene:	CG7497 / 39966	FlyBaseID:	FBgn0036742	Length:	412	Species:	Drosophila melanogaster
Sequence 2:	NP_001025421.1	Gene:	ptger2b / 570410	ZFINID:	ZDB-GENE-040724-267	Length:	341	Species:	Danio rerio

Alignment Length:	363	Identity:	76/363 - (20%)
Similarity:	134/363 - (36%)	Gaps:	132/363 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 GVFGNSLALFIL-ARKKLNKNSKYTLMLRCLATNNLVALLGMLTTTLLKMYLSKEVLQSFIR-VD 104
            ||.||.:||.:| .|::....|.:.:::..|.   :..|||..:       ||..||.::.| ..
Zfish    29 GVLGNVVALILLEMRRRKQPASLFHVLVSSLV---ITDLLGTFS-------LSPLVLTAYFRNAS 83

  Fly   105 CVGL-----------VVWRFFGLSSGCIAAVMAAERWMALARPFIYHKHITYELIRKSINSILMI 158
            .:|:           ....||.:.:..|...||.|||:::..||.|.|:.:......:|..|.::
Zfish    84 LLGMNENRLACGHFAYAMTFFSVVTLAILLSMAVERWLSIGHPFFYEKYSSKRCGYITIALIYLL 148

  Fly   159 AVVITFLPFVGFGAYIDESNPDQLKCIRYRDAPGVW-----------NKTYAVLFMVFGTLLCIV 212
            ..:....||:|||.|           ::|  .||.|           :|.:.:::.....|:.:.
Zfish   149 CALFCVTPFLGFGKY-----------VQY--CPGTWCFIDMDPSASEHKAFNIIYASCLLLMIVC 200

  Fly   213 IVACNLFVAHTLLCVIGRSRTAKRHMHYDLVSRDKNSAISIDPESSSGTTLYQTQLSTGSGNSHR 277
            .|.||..|.:.:      ||..:|.                                    .:||
Zfish   201 TVLCNASVIYHI------SRMYRRL------------------------------------KAHR 223

  Fly   278 -SVQPARQYRHSVSVTMAATDSSPVEIKFAKLMAFLSISFVICWMPQMI---------------- 325
             ||:..|.::...|:|.        |::...|:.|::|:||.|.:|.:|
Zfish   224 SSVRRQRGHKRHRSMTK--------EVEHLVLLWFMTIAFVFCSLPLVIQVYHNTLYHRDRHRNN 280

  Fly   326 AIPLAIAPNRVPASNKFFIIADVLTALHFTSDPYVYVL 363
            .|||            .|:.|:.:.      ||:|:::
Zfish   281 VIPL------------LFLSANPII------DPWVFII 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7497	NP_001287100.1	7tm_4	36..>221	CDD:304433	48/202 (24%)
ptger2b	NP_001025421.1	7tm_4	26..>238	CDD:304433	57/273 (21%)
ptger2b	NP_001025421.1	7tm_1	32..297	CDD:278431	73/355 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	57	1.000	Domainoid score	I10806
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I5323
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D412827at33208
OrthoFinder	1	1.000	-	-		FOG0000857
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11866
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R10330
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	7.100