DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7497 and Ptger3

DIOPT Version :9

Sequence 1:	NP_001287100.1	Gene:	CG7497 / 39966	FlyBaseID:	FBgn0036742	Length:	412	Species:	Drosophila melanogaster
Sequence 2:	XP_038957686.1	Gene:	Ptger3 / 24929	RGDID:	3435	Length:	417	Species:	Rattus norvegicus

Alignment Length:	395	Identity:	94/395 - (23%)
Similarity:	149/395 - (37%)	Gaps:	122/395 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 APPKALYANRNR-----------LIIGVIIMVLGVFGNSLALFILARKKLNKNSK-YTLMLRCLA 72
            ||..::.|:.|:           :...:.:||.|..||:||:.:::|....:.|| ....|.|:.
  Rat     6 APEHSVEAHSNQSSAADGCGSVSVAFPITMMVTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIG 70

  Fly    73 TNNLVALLGMLTTT--LLKMYLSK---EVLQSFIRVDCV--GLVVWRFFGLSSGCIAAVMAAERW 130
            ...|..|:|.|.|:  ::.:|||:   |.|....|: |.  ||.: ..|||||..:|:.||.||.
  Rat    71 WLALTDLVGQLLTSPVVILVYLSQRRWEQLDPSGRL-CTFFGLTM-TVFGLSSLLVASAMAVERA 133

  Fly   131 MALARPFIYHKHITYELIRKSINSILMIAVVITFLPFVGFGAYIDESNPDQLKCIRYRDAPGVW- 194
            :|:..|..|..|:.....|..:..:.:..:....||.:|.|.|          .:::   ||.|
  Rat   134 LAIRAPHWYASHMKTRATRAVLLGVWLSVLAFALLPVLGVGRY----------SVQW---PGTWC 185

  Fly   195 --------NKT----------YAVLFMVFGTLLCIVIVACNLFVAHTLLCVIGRSRTAKRHMHYD 241
                    |:|          :|..|...|.|..:|..||||             .|.|.
  Rat   186 FISTGPAGNETDSAREPGSVAFASAFACLGLLALVVTFACNL-------------ATIKA----- 232

  Fly   242 LVSRDKNSAISIDPESSSGTTLYQTQLSTGSGNSHRSVQPARQYRHSVSVTMAATDSSPVEIKFA 306
            ||||.:..|.:....:..|....:|                                   .|:..
  Rat   233 LVSRCRAKAAASQSSAQWGRITTET-----------------------------------AIQLM 262

  Fly   307 KLMAFLSISFVICWMPQMIAIPLAIAPNRVPASN-----------KFFIIADVLTALHFTSDPYV 360
            .:|..||    :||.|.:|.: |.:..|::....           ..|:||..|.:|:...||:|
  Rat   263 GIMCVLS----VCWSPLLIMM-LKMIFNQMSVEQCKTQMGKEKECNSFLIAVRLASLNQILDPWV 322

  Fly   361 YVLSR 365
            |:|.|
  Rat   323 YLLLR 327

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7497	NP_001287100.1	7tm_4	36..>221	CDD:304433	60/211 (28%)
Ptger3	XP_038957686.1	TM helix 5	203..232	CDD:410628	10/41 (24%)
		TM helix 6	252..282	CDD:410628	10/69 (14%)
		TM helix 7	302..327	CDD:410628	10/24 (42%)
		7tm_GPCRs	26..335	CDD:421689	90/375 (24%)
		TM helix 1	27..53	CDD:410628	7/25 (28%)
		TM helix 2	65..91	CDD:410628	7/25 (28%)
		TM helix 3	107..137	CDD:410628	14/30 (47%)
		TM helix 4	149..171	CDD:410628	3/21 (14%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338666
Domainoid	1	1.000	50	1.000	Domainoid score	I11355
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	57	1.000	Inparanoid score	I5326
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D412827at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11866
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.960