DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7497 and Ptger3

DIOPT Version :9

Sequence 1:	NP_001287100.1	Gene:	CG7497 / 39966	FlyBaseID:	FBgn0036742	Length:	412	Species:	Drosophila melanogaster
Sequence 2:	NP_001346674.1	Gene:	Ptger3 / 19218	MGIID:	97795	Length:	366	Species:	Mus musculus

Alignment Length:	368	Identity:	89/368 - (24%)
Similarity:	143/368 - (38%)	Gaps:	111/368 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 VIIMVLGVFGNSLALFILARKKLNKNSK-YTLMLRCLATNNLVALLGMLTTT--LLKMYLSK--- 94
            :.:||.|..||:||:.:::|....:.|| ....|.|:....|..|:|.|.|:  ::.:|||:
Mouse    33 ITMMVTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTSPVVILVYLSQRRW 97

  Fly    95 EVLQSFIRVDCV--GLVVWRFFGLSSGCIAAVMAAERWMALARPFIYHKHITYELIRKSINSILM 157
            |.|....|: |.  ||.: ..|||||..:|:.||.||.:|:..|..|..|:.....|..:..:.:
Mouse    98 EQLDPSGRL-CTFFGLTM-TVFGLSSLLVASAMAVERALAIRAPHWYASHMKTRATRAVLLGVWL 160

  Fly   158 IAVVITFLPFVGFGAYIDESNPDQLKCIRYRDAPGVW---------NKT----------YAVLFM 203
            ..:....||.:|.|.|          .:::   ||.|         |:|          :|..|.
Mouse   161 SVLAFALLPVLGVGRY----------SVQW---PGTWCFISTGPAGNETDPAREPGSVAFASAFA 212

  Fly   204 VFGTLLCIVIVACNLFVAHTLLCVIGRSRTAKRHMHYDLVSRDKNSAISIDPESSSGTTLYQTQL 268
            ..|.|..:|..||||   .|:..::.|.|.              .:|:|
Mouse   213 CLGLLALVVTFACNL---ATIKALVSRCRA--------------KAAVS---------------- 244

  Fly   269 STGSGNSHRSVQPARQYRHSVSVTMAATDSSPVEIKFAKLMAFLSISFVICWMPQMIAIPLAIAP 333
                       |.:.|:....:.|         .|:...:|..||    :||.|.:|.: |.:..
Mouse   245 -----------QSSAQWGRITTET---------AIQLMGIMCVLS----VCWSPLLIMM-LKMIF 284

  Fly   334 NRVPASN-----------KFFIIADVLTALHFTSDPYVYVLSR 365
            |::....           ..|:||..|.:|:...||:||:|.|
Mouse   285 NQMSVEQCKTQMGKEKECNSFLIAVRLASLNQILDPWVYLLLR 327

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7497	NP_001287100.1	7tm_4	36..>221	CDD:304433	60/211 (28%)
Ptger3	NP_001346674.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..22
		7tm_GPCRs	26..335	CDD:333717	89/368 (24%)
		TM helix 1	28..52	CDD:320095	7/18 (39%)
		TM helix 2	66..88	CDD:320095	7/21 (33%)
		TM helix 3	108..130	CDD:320095	9/22 (41%)
		TM helix 4	153..169	CDD:320095	0/15 (0%)
		TM helix 5	204..227	CDD:320095	7/22 (32%)
		TM helix 6	255..280	CDD:320095	9/38 (24%)
		TM helix 7	302..327	CDD:320095	10/24 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835067
Domainoid	1	1.000	54	1.000	Domainoid score	I11155
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	65	1.000	Inparanoid score	I5355
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11866
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R10330
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.980