Protein Alignment CG7497 and ADRA1B

DIOPT Version :9

• Sequence 1: NP_001287100.1
• Gene: CG7497 / 39966
• FlyBaseID: FBgn0036742
• Length: 412
• Species: Drosophila melanogaster
• Sequence 2: XP_011532737.1
• Gene: ADRA1B / 147
• HGNCID: 278
• Length: 556
• Species: Homo sapiens
• Alignment Length: 469
• Identity: 94/469 - (20%)
• Similarity: 168/469 - (35%)
• Gaps: 142/469 - (30%)

  Fly     3 TTTPVLDLLMPHNSTTVAPPKALYANRNRLIIGVIIMVLGVFGNSLALFILA-RKKLNKNSKYTL 66
            :|.|.||:           .:|:...   |::|..|: ..:.||.|.:..:| .:.|...:.|.:
Human    35 STLPQLDI-----------TRAISVG---LVLGAFIL-FAIVGNILVILSVACNRHLRTPTNYFI 84

  Fly    67 MLRCLATNNLVALLGMLTTTLLKMYLSKEVLQSFI--RVDCVGLVVWRFFGLSSGCIAAVM---- 125
            :       ||.....:|:.|:|....:.|||..::  |:.|   .:|....:.. |.|:::
Human    85 V-------NLAMADLLLSFTVLPFSAALEVLGYWVLGRIFC---DIWAAVDVLC-CTASILSLCA 138

  Fly   126 -AAERWMALARPFIYHKHITYELIRKSINSILMIAVVITFLPFVGFGAYIDESNP-DQLKCIRYR 188
             :.:|::.:.....|...:|......::.|:.:::.||:..|.:|:    .|..| |..:|
Human   139 ISIDRYIGVRYSLQYPTLVTRRKAILALLSVWVLSTVISIGPLLGW----KEPAPNDDKEC---- 195

  Fly   189 DAPGVWNKTYAVLFMVFGT----LLCIVIVACNLFVAHTLLCVIGRSRTAK-------RHMHYDL 242
               ||..:.:..||...|:    |..|:::.|.:::.        ..||.|       :.|
Human   196 ---GVTEEPFYALFSSLGSFYIPLAVILVMYCRVYIV--------AKRTTKNLEAGVMKEM---- 245

  Fly   243 VSRDKNSAISIDPESSSGTTLYQTQLSTGSGNSHRSVQPARQYRHSVSVTMAATDSSPVEIKFAK 307
             |..|...:.|..::....||..|:   ..|::.||....:.::.|            .|.|.||
Human   246 -SNSKELTLRIHSKNFHEDTLSSTK---AKGHNPRSSIAVKLFKFS------------REKKAAK 294

  Fly   308 LMAFLSISFVICWMPQMIAIPL--------------------------AIAPNRVPASNKFF--- 343
            .:..:...|::||:|..||:||                          .:.|.....|...|
Human   295 TLGIVVGMFILCWLPFFIALPLDPDSPPPTHLRVVPAPWGHSSIMNLPLVLPLDATRSGSLFSTL 359

  Fly   344 -----IIADVLTALHFTS--DPYVYVLS---------------------RSKSINWSLLGCIKRW 380
                 :...|....:|.|  :|.:|..|                     |.:.....|.||...:
Human   360 KPPDAVFKVVFWLGYFNSCLNPIIYPCSSKEFKRAFVRILGCQCRGRGRRRRRRRRRLGGCAYTY 424

  Fly   381 RSGWRPGGLRRSQS 394
            |...|.|.|.||||
Human   425 RPWTRGGSLERSQS 438

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7497	NP_001287100.1	7tm_4	36..>221	CDD:304433	40/197 (20%)
ADRA1B	XP_011532737.1	7tm_4	57..>181	CDD:304433	25/135 (19%)
		7tm_1	62..384	CDD:278431	72/371 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910