Protein Alignment CG7497 and ptger2

DIOPT Version :10

• Sequence 1: NP_648999.2
• Gene: CG7497 / 39966
• FlyBaseID: FBgn0036742
• Length: 412
• Species: Drosophila melanogaster
• Sequence 2: XP_031747410.1
• Gene: ptger2 / 100493226
• XenbaseID: XB-GENE-967341
• Length: 407
• Species: Xenopus tropicalis
• Alignment Length: 408
• Identity: 92/408 - (22%)
• Similarity: 155/408 - (37%)
• Gaps: 100/408 - (24%)

  Fly    41 LGVFGNSLALFILARKKLNKNSKYTLMLRCLATNNLVA-LLG--MLTTTLLKMYLSKEVLQSFIR 102
            |||.||.:||.:|..::.....|.:| ...|||..::. |:|  ||:..:|..|.|...|::...
 Frog    30 LGVLGNLIALVLLEHRRRGIRGKISL-FHILATGLVITDLMGTCMLSPVVLSAYSSNLTLKALGG 93

  Fly   103 VDCVGLVV-------WRFFGLSSGCIAAVMAAERWMALARPFIYHKHITYELIRKSINSILMIAV 160
            .|  ..:|       ..||.|::..:...||.||.||:..|:.|.|.|:...      .::|..|
 Frog    94 SD--NFIVCHYFAFAMTFFSLATMLVLFAMALERAMAIGHPYFYEKFISKRC------GLVMFPV 150

  Fly   161 VITF------LPFVGFGAYIDESNPDQLKCIRYRDAPGVW-----------NKTYAVLFMVFGTL 208
            :.:|      .|.:|.|.|           |:|  .||.|           ..|..|...::.||
 Frog   151 IYSFCIFFCLFPAMGAGEY-----------IQY--CPGTWCFINMRGQHIDGSTSNVYSTLYATL 202

  Fly   209 LCIVIVA---CNLFVAHTLLCVIGRSRTAKRHMHYDLVSRDKNSAIS--IDP------------- 255
            |.|||:|   ||..|   ::.::...:..|..:...:|::.:..::|  ||.
 Frog   203 LLIVIIAVLTCNFIV---IISLVRMHKRQKSRLGSLMVTKKERMSMSEEIDHLILLSLMTIIFFI 264

  Fly   256 -------ESSSGTT--------LYQTQLSTGSGNSHRSVQPARQYRHSVSVTMAATDSSPVEIKF 305
                   .||.|..        |:...:..|....:...|..:.|.:.........|...:.::|
 Frog   265 CSVPFTCRSSKGNEGLFSKNPGLWAKLIKEGLSRENEFTQEVQVYMNRFCPDCHNDDRDLLALRF 329

  Fly   306 AKLMAFLSISFVICWMPQMIAIPLAIAPNRVPASNKFFIIADVLTALHFTSDPYVYVLSRSKSIN 370
               ::|.||  :..|:..::..|:......|....|.|.|.::..:...||.     ||.:|..|
 Frog   330 ---LSFNSI--IDPWVFTILRPPVLRLMRYVLCCQKTFKIKEIAKSPSLTSR-----LSNTKLTN 384

  Fly   371 WSLLGCIKRWRSGWRPGG 388
            ..:     ::.|..:|.|
 Frog   385 VDI-----KYGSAQKPDG 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7497	NP_648999.2	7tm_GPCRs	34..365	CDD:475119	86/383 (22%)
		TM helix 1	34..55	CDD:410628	8/13 (62%)
		TM helix 2	68..87	CDD:410628	7/21 (33%)
		TM helix 3	99..127	CDD:410628	6/34 (18%)
		TM helix 4	150..166	CDD:410628	3/21 (14%)
		TM helix 5	195..218	CDD:410628	10/25 (40%)
		TM helix 6	306..328	CDD:410628	4/21 (19%)
		TM helix 7	340..365	CDD:410628	6/24 (25%)
ptger2	XP_031747410.1	7tmA_PGE2_EP2	18..353	CDD:320267	79/352 (22%)
		TM helix 1	19..45	CDD:320267	8/14 (57%)
		TM helix 2	56..82	CDD:320267	8/25 (32%)
		TM helix 3	100..130	CDD:320267	9/29 (31%)
		TM helix 4	142..164	CDD:320267	4/27 (15%)
		TM helix 5	191..220	CDD:320267	12/31 (39%)
		TM helix 6	246..311	CDD:320267	10/64 (16%)
		TM helix 7	320..345	CDD:320267	6/29 (21%)