Protein Alignment CG7497 and ptger4b

DIOPT Version :10

• Sequence 1: NP_648999.2
• Gene: CG7497 / 39966
• FlyBaseID: FBgn0036742
• Length: 412
• Species: Drosophila melanogaster
• Sequence 2: NP_001121839.1
• Gene: ptger4b / 100005416
• ZFINID: ZDB-GENE-060531-102
• Length: 497
• Species: Danio rerio
• Alignment Length: 439
• Identity: 100/439 - (22%)
• Similarity: 172/439 - (39%)
• Gaps: 113/439 - (25%)

  Fly     9 DLLMPHNSTTVAPPKALYANRNRLIIGVIIMVLGVFGNSLALFIL--ARKKLNKNSKYTLMLRCL 71
            |:.:..|:|..:..|......|...|.||:.::||.||.:|:.:|  :||:..:.:.|||:  |
Zfish    26 DMDLQLNATNNSVVKMSKTTLNGYPIPVIMFIVGVVGNVIAIVVLRKSRKEQKETTFYTLV--C- 87

  Fly    72 ATNNLVALLGMLTTTLLKMYLSKEV-LQSFIRVDCVGLV--------VWRFFGLSSGCIAAVMAA 127
                     |:..|.||...|:..| :.::::.:..|.:        :..||.|:...|...|:.
Zfish    88 ---------GLAVTDLLGTLLASPVTIATYVKGEWPGGMPLCQYSGFILLFFSLAGLSIICAMSV 143

  Fly   128 ERWMALARPFIYHKHITYELIRKSINSILMIAVVITFLPFVGFGAYIDESNPDQLKCIRYRDAPG 192
            ||::|:...:.|:.::...:...::..|.:...:...||.:|.|:.:.:.             ||
Zfish   144 ERYLAINHAYFYNHYVDQRVAGLTLGGIYVSNALFCALPSMGLGSVVIQH-------------PG 195

  Fly   193 VW------NK------TYAVLFMVFGTLLCIVIVACNLFVAHTLLCVIGRSRTAKRHMHYDLVSR 245
            .|      ||      |::.::..|.::|.:..|.||:.|...|:.           ||...|.|
Zfish   196 TWCFIDWHNKTDTTTATFSYMYASFSSVLILATVVCNVLVCAALIM-----------MHKRFVRR 249

  Fly   246 DKNSAISIDPESSSGTTLYQTQLSTGSGNSHRSVQPARQYRHSVSVTMAATDSSPVEIKFAKLMA 310
                                |.|.|..|.    |...|:.|....:..|       ||:...::.
Zfish   250 --------------------TSLGTDQGR----VAEIRRRRSFARLAAA-------EIQMVIVLI 283

  Fly   311 FLSISFVICWMPQMI----------AIPLAIAPNRVPASNKFFIIADVLTALHFTSDPYVYVLSR 365
            ..|...:||..|.::          |...:..||..| ..|...||.|...|    ||::|:|.|
Zfish   284 ATSTVVLICSTPLVVQVFVNQLFNSAADSSARPNPDP-DLKAIRIASVNPIL----DPWIYILLR 343

  Fly   366 SKSINWSLLGCIK--RWRSGWRPGGLRRSQSD---QSRMRTTMTEANTL 409
             |::...:|..||  ..|.|.|  ..||:.||   .:.:||:...:..|
Zfish   344 -KTVVQKILEKIKCLFCRIGGR--SHRRNTSDFHCDNDLRTSSVVSRDL 389

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7497	NP_648999.2	7tm_GPCRs	34..365	CDD:475119	80/363 (22%)
		TM helix 1	34..55	CDD:410628	9/22 (41%)
		TM helix 2	68..87	CDD:410628	3/18 (17%)
		TM helix 3	99..127	CDD:410628	6/35 (17%)
		TM helix 4	150..166	CDD:410628	1/15 (7%)
		TM helix 5	195..218	CDD:410628	7/28 (25%)
		TM helix 6	306..328	CDD:410628	5/31 (16%)
		TM helix 7	340..365	CDD:410628	9/24 (38%)
ptger4b	NP_001121839.1	7tmA_PGE2_EP4	51..351	CDD:320270	82/372 (22%)
		TM helix 1	51..73	CDD:320270	9/21 (43%)
		TM helix 2	82..108	CDD:320270	10/37 (27%)
		TM helix 3	120..150	CDD:320270	8/29 (28%)
		TM helix 4	162..184	CDD:320270	3/21 (14%)
		TM helix 5	209..238	CDD:320270	7/28 (25%)
		TM helix 6	273..303	CDD:320270	7/36 (19%)
		TM helix 7	318..343	CDD:320270	10/29 (34%)