DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7497 and ptger3

DIOPT Version :9

Sequence 1:	NP_001287100.1	Gene:	CG7497 / 39966	FlyBaseID:	FBgn0036742	Length:	412	Species:	Drosophila melanogaster
Sequence 2:	XP_017212135.1	Gene:	ptger3 / 100000544	ZFINID:	ZDB-GENE-120508-5	Length:	401	Species:	Danio rerio

Alignment Length:	397	Identity:	83/397 - (20%)
Similarity:	153/397 - (38%)	Gaps:	117/397 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LMPHN----STTVAPPKALYANRNRLIIGVIIMVLGVFGNSLALFIL---ARKKLNKNSKYTLML 68
            :||.:    |:..:|.::.......:...:.:||.|:.|||||:.::   .|||.||..:..|:
Zfish    19 IMPDSNISKSSQDSPGRSAGCGSVSVFFPITMMVTGMVGNSLAMLLVYSAYRKKENKRKRSFLL- 82

  Fly    69 RCLATNNLVALLGMLTTT--LLKMYLSKEVLQSFIRVD-----CVGL-VVWRFFGLSSGCIAAVM 125
             |:.:..|..|.|.|.|:  ::.:|.:.   ..:.|||     |... |....|||....:|:.|
Zfish    83 -CIGSLALTDLFGQLLTSPIVISVYRAD---MKWDRVDPSKTLCAFFGVCMTTFGLCPLFLASAM 143

  Fly   126 AAERWMALARPFIYHKHITYELIRKSINSILMIAVVITFLPFVGFGAYIDESNPDQLKCIRYRDA 190
            |.||.:|:..|..|..::...:.::.:..|..:.::...||..|.|.|          .:::
Zfish   144 AIERALAIIAPHWYSHYMKTSVTKQVLVIIWCLVLLFALLPIAGVGEY----------TLQW--- 195

  Fly   191 PGVW------------NKTYAVLFMVFGTLLCIVIVACNLFVAHTLLCVIGRSRTAKRHMHYDLV 243
            ||.|            |..:|..|...|....:|.::||:.   |:..::.|.:|
Zfish   196 PGTWCFINTGDKDVTGNTFFATTFAALGIFSLLVTLSCNVV---TIRALVTRCKT---------- 247

  Fly   244 SRDKNSAISIDPESSSGTTLYQTQLSTGSGNSHRSVQPARQYRHSVSVTMAATDSSPVEIKFAKL 308
               |:|                            |.|.::|:....:.|:            .:|
Zfish   248 ---KSS----------------------------STQSSKQWERLTTETV------------IQL 269

  Fly   309 MAFLSISFVICWMPQMIAI---------------PLAIAPNRVPASNKFFIIADVLTALHFTSDP 358
            |..:.: .:.||.|.::.:               ..:::|..:.....||:.|..|.:|:...||
Zfish   270 MGIMCV-LLTCWSPLLVLMLKMILTHTSSHHCYSAGSLSPQELQKDCNFFLTAIRLASLNQILDP 333

  Fly   359 YVYVLSR 365
            :||:|.|
Zfish   334 WVYLLLR 340

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7497	NP_001287100.1	7tm_4	36..>221	CDD:304433	53/207 (26%)
ptger3	XP_017212135.1	7tm_4	48..>238	CDD:304433	53/210 (25%)
ptger3	XP_017212135.1	7tm_1	57..336	CDD:278431	72/353 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578212
Domainoid	1	1.000	57	1.000	Domainoid score	I10806
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I5323
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D412827at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11866
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R10330
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	8	7.990