Protein Alignment anchor and anchor

DIOPT Version :10

• Sequence 1: NP_001261995.1
• Gene: anchor / 39965
• FlyBaseID: FBgn0036741
• Length: 957
• Species: Drosophila melanogaster
• Sequence 2: XP_061505044.1
• Gene: anchor / 1270107
• VectorBaseID: AGAMI1_011424
• Length: 1003
• Species: Anopheles gambiae
• Alignment Length: 993
• Identity: 585/993 - (58%)
• Similarity: 732/993 - (73%)
• Gaps: 71/993 - (7%)

  Fly     3 SSMYYASQRIAASTEANVRVITSTMASS-LANGT--------ATPR---ADDGG--VSMNNFYPA 53
            |.:::....||  |...:..:..|:|:: ..|||        .||:   .|||.  :||:|.|||
Mosquito    44 SGLHHPPSPIA--TIVGLPALLDTVATTPFHNGTFGAGGLISTTPQNDTGDDGAPTISMDNLYPA 106

  Fly    54 LVQCFGIIICGYIAGRFKIISNAETKGLGTFVGTFALPSLIFLSLVELNWSAVNWSFLLAMLVSK 118
            |:|||.||||||:|||..||||.|.|||.||||||||||:|||||.||:||.|||:|||::|::|
Mosquito   107 LIQCFAIIICGYLAGRLNIISNFEAKGLNTFVGTFALPSVIFLSLAELDWSTVNWNFLLSILIAK 171

  Fly   119 AVVFFAVLIISLLVARPLNYARGGLMAIFCTQSNDFAIGYPIVMALYKDVHPEYASYLYLMAPIS 183
            .:||.:|.|||||||||:||.|.||:|||||||||||||||||.|||..:|||||||:||:||||
Mosquito   172 TIVFLSVAIISLLVARPVNYGRAGLLAIFCTQSNDFAIGYPIVSALYSKIHPEYASYIYLLAPIS 236

  Fly   184 LAILNPVGLVLMEISKIIKNK---------EDVTRNPPLCPETCPAEQMSKRNR--CLGERSILV 237
            ||||||:|.||||||| ||.|         |:....||.||      ||:.:||  .|..::::|
Mosquito   237 LAILNPIGFVLMEISK-IKEKNAENNTSADEEANAPPPACP------QMAAQNRRKILKGKALVV 294

  Fly   238 FNTLIALFFNPLLLMTLLGVAGGFLFPNGLPEMVSSTLRVLGQSFSATALFLLGLKIVGGTGSER 302
            |..:.::||||:||||||||.||.:||||||..:||.||.||.||||||||||||::| |..|..
Mosquito   295 FKMIESIFFNPILLMTLLGVIGGQIFPNGLPVYLSSVLRSLGNSFSATALFLLGLRMV-GKASAL 358

  Fly   303 KSIGFLLPGVLILVKILVLPLVIRQTVNIMQSGQNFNDTTELSTFGFLYGTFPAAPGAFVIATQY 367
            :..|.:|||:|||||:||.|||.|||||||.:|.||::||:||||||||||||||||.||||:||
Mosquito   359 QGPGLILPGILILVKLLVFPLVTRQTVNIMNAGANFSETTDLSTFGFLYGTFPAAPGVFVIASQY 423

  Fly   368 NMEVELVARSMVFCTFISAPLMFISAKMISLTNLKPLDYLHELDAFSFDISVAGAAACCIMLALL 432
            |.:|:|:|.|||..|||||||||||||||::|||.|.|||:|||.||||||:....|....|.|.
Mosquito   424 NRDVDLIATSMVASTFISAPLMFISAKMITITNLTPADYLNELDKFSFDISIVAIVAGVWTLLLF 488

  Fly   433 IVTKRFKRMPQRITFCLVLSQLMCCIGVILWSKMEHVHRWPLYLQFLLFNIGTYSTRLWTGLLAI 497
            .:|::.||||.|||.||::|||:|.:||||||.:|...||.:||||..|.||.||:||||..|||
Mosquito   489 ALTRKVKRMPHRITCCLLVSQLICNVGVILWSTLEQNSRWKMYLQFYFFTIGCYSSRLWTAFLAI 553

  Fly   498 SLLFLQCRSLCFVLKLWPYMLVFAWGVPAVLSALLIAFDS-NVMSGEKHNPSFQYGNAQAAISVF 561
            ::||||||||||||||||..:..|||:|.::.:||:..|| |::..||.|||||||||||||:||
Mosquito   554 TILFLQCRSLCFVLKLWPVFIAAAWGLPTLIVSLLLFVDSKNIVPTEKRNPSFQYGNAQAAIAVF 618

  Fly   562 MLVMCFIVTVGCLVLHQRYKKRYEKYMTYSRELSNPESESSDLHSTISTTNLLSHTDQSSIRQSV 626
            :||||||||||||:||||:|||:|:|:|.|||:|:|:::||.: :|.|..|||:....:|.....
Mosquito   619 LLVMCFIVTVGCLILHQRFKKRHERYLTLSREVSSPDADSSPV-TTSSVVNLLADGGGNSTIHQR 682

  Fly   627 RTASYSSSSDDEEMIPTAAGLPTSRSNGAASGGAGSGGGGCG----SGNGTCCSG------GAPV 681
            |..|.:||  |:|::|...        .||:..|.|.|||||    :.||:.||.      |...
Mosquito   683 RRRSVTSS--DDEILPARI--------VAAAAAAASVGGGCGTAPPAANGSACSSDGRGGTGGCC 737

  Fly   682 SNSSTTSTVVVDIEDLLNRTRQRASGAN-NKDLNKIESAPATEEIRNQ-MCSSSFNCGPSTSRQS 744
            |:||.|...|||||||       |.||: |.|:|:    |.:..::.. |||:.||| |:..:|.
Mosquito   738 SSSSGTIRTVVDIEDL-------AIGASINNDVNE----PGSSTLQTSGMCSAQFNC-PAAGKQQ 790

  Fly   745 CQTIIERYEDQNRRGLEPLEHPSDADEHQTLKHTVLLITLLCSMFVGLAVSIWTLVMEGMSGIYL 809
            ||::|:||.:|...||||:|:....|:.|.|:|.||||.|||||||||::|:|||:||||||||:
Mosquito   791 CQSLIDRYREQANDGLEPVEYDKTGDQQQILRHMVLLILLLCSMFVGLSLSVWTLIMEGMSGIYV 855

  Fly   810 ELSFLDAFLNFGQGLIVLAVFITDIGELLMPVVKLWRKLWYGANVVSLPHWSNVRPETKHICEQF 874
            ||:||||||||||.:||||||:||.||||:|::|.|||:|||||::.||.||::..||:|||:||
Mosquito   856 ELTFLDAFLNFGQCIIVLAVFVTDTGELLLPMMKFWRKVWYGANLLQLPIWSDLSTETRHICDQF 920

  Fly   875 RNHHLENCKKDIAKDRRWRIRVYRRVFYGTEFVSWLIEVGLSKDRMEAVHYARHLVDGRVLRHIN 939
            ..||||.|:|.||||.||||:||||||||:.||.||:||||:|||.:|.||||.|:|||||||||
Mosquito   921 TTHHLEVCRKAIAKDIRWRIKVYRRVFYGSVFVDWLLEVGLAKDRTDATHYARRLIDGRVLRHIN 985

  Fly   940 NVYHFEDKLLLYNFCSRI 957
            |||||.|:.|||.||.|:
Mosquito   986 NVYHFHDRNLLYTFCERL 1003

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
anchor	NP_001261995.1	YfdV	47..391	CDD:440443	236/354 (67%)
		7tm_GPCRs	429..>536	CDD:475119	63/106 (59%)
		TM helix 2	442..460	CDD:410628	10/17 (59%)
		TM helix 3	475..497	CDD:410628	14/21 (67%)
		TM helix 4	516..532	CDD:410628	4/15 (27%)
		DEP_GPR155	871..953	CDD:239890	60/81 (74%)
anchor	XP_061505044.1	None