DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vps60 and chmp5

DIOPT Version :9

Sequence 1:	NP_001261994.1	Gene:	Vps60 / 39964	FlyBaseID:	FBgn0036740	Length:	226	Species:	Drosophila melanogaster
Sequence 2:	NP_001016748.1	Gene:	chmp5 / 549502	XenbaseID:	XB-GENE-5962693	Length:	219	Species:	Xenopus tropicalis

Alignment Length:	222	Identity:	140/222 - (63%)
Similarity:	172/222 - (77%)	Gaps:	3/222 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MNRLFGRGKPKEPGPSLNDCIAGVDARATNIEEKISNLEAELRKYREQMSKMREGPAKNSVKQKA 65
            ||||||:.|||.|..:|.|||:.||:|:.:|::|||.|:|||.||::||.||||||:||.|||||
Frog     1 MNRLFGKSKPKVPPSTLTDCISNVDSRSESIDKKISRLDAELVKYKDQMKKMREGPSKNMVKQKA 65

  Fly    66 LRVLKQKKAYEQQAESLRNQSFNMEQANYAAQSLKDTQATVAAMKDGVKQMKTEYKKINIDQIED 130
            |||||||:.||||.::|..|||||||.|||.||||||:.||.|||.|.|:||..||::.||||||
Frog    66 LRVLKQKRMYEQQRDNLNQQSFNMEQTNYAIQSLKDTKTTVDAMKVGAKEMKKAYKQVKIDQIED 130

  Fly   131 IQDDMADMFEQADEVQEALGRTYGMPEVDDDDLQAELDALGDEIALDDDTSYLDDVVKAPEAPSR 195
            :||.:.||.|.|:|:||||.|:||.||:|:|||:|||||||||:.|||||||||:...||..|..
Frog   131 LQDQLEDMMENANEIQEALSRSYGTPEIDEDDLEAELDALGDELLLDDDTSYLDEAASAPAIPEG 195

  Fly   196 EPGADSIVPGKSTIETDEFGLPKIPTS 222
            .|. ||  ..|..:..||||||:||.:
Frog   196 VPN-DS--KNKDGVLVDEFGLPQIPAT 219

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vps60	NP_001261994.1	Snf7	1..190	CDD:304451	125/188 (66%)
chmp5	NP_001016748.1	Snf7	1..201	CDD:328813	131/202 (65%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	247	1.000	Domainoid score	I2114
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5757
Inparanoid	1	1.050	282	1.000	Inparanoid score	I2821
OMA	1	1.010	-	-		QHG53573
OrthoDB	1	1.010	-	-		D1301560at2759
OrthoFinder	1	1.000	-	-		FOG0003367
OrthoInspector	1	1.000	-	-		oto102734
Panther	1	1.100	-	-	LDO	PTHR22761
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2003
SonicParanoid	1	1.000	-	-		X3249
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.110