DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Eip74EF and gabpa

DIOPT Version :9

Sequence 1:	NP_001014590.1	Gene:	Eip74EF / 39962	FlyBaseID:	FBgn0000567	Length:	883	Species:	Drosophila melanogaster
Sequence 2:	NP_001315341.1	Gene:	gabpa / 58110	ZFINID:	ZDB-GENE-011010-2	Length:	455	Species:	Danio rerio

Alignment Length:	151	Identity:	59/151 - (39%)
Similarity:	80/151 - (52%)	Gaps:	25/151 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   736 SQSVIQPATSSVSYDLSYMLELGGFQQ---------RKAKKPRKPKLEMGVKRRSREGSTT---- 787
            ||...|.||  |:.|....:.....||         :..|.||.|::  ..:.||..|:.|
Zfish   248 SQDQSQEAT--VTIDQPVQIIPAPVQQATPTAIKVMKHNKTPRAPRI--SGEERSSPGNRTGNNG 308

  Fly   788 --YLWEFLLKLLQDREY--CPRFIKWTNREKGVFKLVDSKAVSRLWGMHKNKPDMNYETMGRALR 848
              .||:|||:||.|::.  |   |.|.. |:|.|||...:.|::.||..||||.||||.:.||||
Zfish   309 QIQLWQFLLELLTDKDSRDC---ISWVG-EEGEFKLNQPELVAQKWGQRKNKPTMNYEKLSRALR 369

  Fly   849 YYYQRGILAKVDGQRLVYQFV 869
            |||...:::||.|:|.||:||
Zfish   370 YYYDGDMISKVQGKRFVYKFV 390

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Eip74EF	NP_001014590.1	Ets	789..869	CDD:278602	40/81 (49%)
gabpa	NP_001315341.1	GABP-alpha	40..118	CDD:288472
		SAM_PNT-GABP-alpha	162..248	CDD:176084	59/151 (39%)
		ETS	309..394	CDD:197710	42/86 (49%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910