DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Eip74EF and Elf4

DIOPT Version :9

Sequence 1:	NP_001014590.1	Gene:	Eip74EF / 39962	FlyBaseID:	FBgn0000567	Length:	883	Species:	Drosophila melanogaster
Sequence 2:	NP_001368805.1	Gene:	Elf4 / 56501	MGIID:	1928377	Length:	655	Species:	Mus musculus

Alignment Length:	125	Identity:	84/125 - (67%)
Similarity:	98/125 - (78%)	Gaps:	6/125 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   761 QQRKAKKPRK------PKLEMGVKRRSREGSTTYLWEFLLKLLQDREYCPRFIKWTNREKGVFKL 819
            :.||.|..|.      |.:.:..|.:..:|||.|||||||.|||||..||::||||.||||:|||
Mouse   176 RNRKTKNNRSTSPVTDPSMPIRKKSKDGKGSTIYLWEFLLALLQDRNTCPKYIKWTQREKGIFKL 240

  Fly   820 VDSKAVSRLWGMHKNKPDMNYETMGRALRYYYQRGILAKVDGQRLVYQFVDVPKDIIEID 879
            |||||||:|||..|||||||||||||||||||||||||||:||||||||.::|||::.||
Mouse   241 VDSKAVSKLWGKQKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKEMPKDLVVID 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Eip74EF	NP_001014590.1	Ets	789..869	CDD:278602	68/79 (86%)
Elf4	NP_001368805.1	Elf-1_N	2..103	CDD:403506
		RUNX1-binding. /evidence=ECO:0000250\|UniProtKB:Q99607	86..205		6/28 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	136..202		6/25 (24%)
		Ets	209..289	CDD:395126	68/79 (86%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	301..362		84/125 (67%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	493..512
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	155	1.000	Domainoid score	I4218
eggNOG	1	0.900	-	-		E1_KOG3804
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm42817
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11849
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.870