DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Eip74EF and elf2

DIOPT Version :9

Sequence 1:	NP_001014590.1	Gene:	Eip74EF / 39962	FlyBaseID:	FBgn0000567	Length:	883	Species:	Drosophila melanogaster
Sequence 2:	XP_012815319.1	Gene:	elf2 / 448422	XenbaseID:	XB-GENE-853311	Length:	588	Species:	Xenopus tropicalis

Alignment Length:	319	Identity:	125/319 - (39%)
Similarity:	178/319 - (55%)	Gaps:	54/319 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   596 TAAASQRGTTI-----NGYHSLHQQQQQ--------QQQSQQSQQQQQLAHQQLSHQQQQALHQQ 647
            |:||...|.::     ||..:|.|::.|        .:....::.:|..|.|.|.:..:..:.|.
Frog     2 TSAAVDGGGSVGDIVSNGVENLEQEEVQVTEYPAVIVEPVPSARLEQGYAAQVLVYDDETFMMQD 66

  Fly   648 LSHQQQQQQQQQQQHPHSQLNGPHPHSHPHSHPHSHPHAGQHTHSTIAAAAA---AAAASVVSSS 709
            .: ::.:.:.:..:...:.::|.:.|.               |..||.||.|   ..:.:::..:
Frog    67 FA-EEHEVETECVEIVEASVHGSNVHC---------------TDKTIEAAEALLHMESPTILRDT 115

  Fly   710 SSAVAAAAMLSASAAAAATAAAAAGG-SQSVIQPAT------SSVSYDLSYMLELGGFQQRKAKK 767
            .|.|........|......||..... :::|::.:|      .|.|..:|  :|||. ..:|.|.
Frog   116 RSPVEVYVPPCVSTPEFIHAAMRPDVITETVVEVSTEDSEPMDSTSIPIS--IELGE-PMKKKKA 177

  Fly   768 PRKPKL----------EMGVKRRSRE--GSTTYLWEFLLKLLQDREYCPRFIKWTNREKGVFKLV 820
            .||||:          |:|:|::.||  |:|||||||||.||||:..|||:||||.||||:||||
Frog   178 GRKPKMQQPAFPNGSPELGIKKKQREGKGNTTYLWEFLLDLLQDKNTCPRYIKWTQREKGIFKLV 242

  Fly   821 DSKAVSRLWGMHKNKPDMNYETMGRALRYYYQRGILAKVDGQRLVYQFVDVPKDIIEID 879
            ||||||||||.||||||||||||||||||||||||||||:||||||||.::||:|:.|:
Frog   243 DSKAVSRLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKEMPKNIVVIE 301

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Eip74EF	NP_001014590.1	Ets	789..869	CDD:278602	70/79 (89%)
elf2	XP_012815319.1	Elf-1_N	3..109	CDD:372034	21/121 (17%)
		Ets	211..290	CDD:365925	69/78 (88%)
		Herpes_BLLF1	<320..>484	CDD:282904
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	156	1.000	Domainoid score	I4136
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006321
OrthoInspector	1	1.000	-	-		otm47927
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3979
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.940