Protein Alignment Eip74EF and pnt

DIOPT Version :10

• Sequence 1: NP_730288.1
• Gene: Eip74EF / 39962
• FlyBaseID: FBgn0000567
• Length: 883
• Species: Drosophila melanogaster
• Sequence 2: NP_524461.2
• Gene: pnt / 42757
• FlyBaseID: FBgn0003118
• Length: 718
• Species: Drosophila melanogaster
• Alignment Length: 942
• Identity: 189/942 - (20%)
• Similarity: 299/942 - (31%)
• Gaps: 342/942 - (36%)

  Fly     8 VAASAHNFASQAAASLVNVSSSSSSSSSSSSSSLSLSSSSSSSSLSSATPTPVASPVTPTSPPPA 72
            ||::|.:|..:||..|..:::.:.....|.:|| .|:|..|.|.||...
  Fly    33 VASTASHFLDKAAHELFQLNAINGHLFKSPASS-HLNSVGSPSILSQLN---------------- 80

  Fly    73 AAAPAEASPPAGAELQEDGQQAKTQEDPTMKDQDMLEKTRQEVKDPVNVEEPGAIVDTESVMARQ 137
                     ..|......||.:      ||:    |:|.|:       |....::|:::::..::
  Fly    81 ---------GIGNSGNHSGQVS------TMR----LKKNRK-------VTFLSSLVESKNIFIKE 119

  Fly   138 SP----------SPV----ASTKVPESL-----------EEISNKSPPVQEDEEESESVASDCRE 177
            .|          |.:    ||.:||.:|           .|:...|....|.|.:..::..|.||
  Fly   120 EPIHGCKDLCSLSDISDHEASLEVPTALPPLTPGTNRKVNEVLKASFASWEKEVQKCNITKDPRE 184

  Fly   178 F---KVLY------NHLRQQQHHHSPSSPDKTRSTLD------------DVSKILWERKQQLQRS 221
            :   .|:|      |.......:..|....|.|:.:|            ....||||....||:.
  Fly   185 WTEEHVIYWLNWAKNEFSLVSMNLDPFYKMKGRAMVDLGKEKFLAITPPFTGDILWEHLDILQKD 249

  Fly   222 SVITAAPTLQPQQHQQPMSDIEDEETLEDVDDADADVEADAEDEELL----EQYQNGYDSPLD-- 280
            .             ::|..||....:.|....|    .....|.::.    |.:.|..:|.::
  Fly   250 C-------------EKPNEDIVHGNSFESATTA----SVCGSDHQVANYPNETHANSNNSSINSR 297

  Fly   281 LSLGGATSAAASAAAAASAVSRRRGRTYSGTESDDSAQCERARMRLKPERKAERSAAYKKSLMKR 345
            ||:...|||..|........:......|:.:.:.|.
  Fly   298 LSMDYVTSAGNSDNKNFHRATPHSHNGYNTSNTHDR----------------------------- 333

  Fly   346 YYTEIPIVKQSTSPAPQQQLQQQHHLQQQQQQQPH-NGSTFAGATALLHIKTEQNTLLTPLQLQQ 409
                   :..||.|            ||||.|||. |||..|.:       ...|::|.| .:||
  Fly   334 -------INNSTPP------------QQQQSQQPTVNGSGSASS-------NNNNSMLPP-AVQQ 371

  Fly   410 QQQQQQGLHGAAGNGGSSNGNNAHQQQQPLAIPQRPLLHNLLSGGAIHNPHHRNYTTATTGSF-- 472
            ...:......:..|..|:|.||:...            :|..:|...:|.::.|.......:.
  Fly   372 SNNENNNTSSSNTNNSSNNNNNSGGS------------NNSNAGSNNNNNNNNNINFMAAAAIFQ 424

  Fly   473 -----PPSPADSGVSDVDSSSSGGQPCADELKARLGMPPATSASAAAAAAAAAAAAAHLHT---G 529
                 .|...:..:......|:......|  .:..|:|                  |||..   |
  Fly   425 HHLKEEPGTQNGNIGGYGGGSNSQNDPTD--LSSYGLP------------------AHLAAYGGG 469

  Fly   530 TFLHPNLYQNNAANSLRNIWNRSVGVPD--NYYGSSGAGSGGTQPGGPGNPQTPGYLTTSYFNAP 592
            :...|...:::......:.::.::...|  :...|.|.||||...|..||  :.|||.:|
  Fly   470 SGSGPTGGRSSGGGGDESDYHSTISAQDHQSQQSSGGNGSGGASGGSTGN--SNGYLDSS----- 527

  Fly   593 TAATAAASQRGTTINGYHSLHQQQQQQQQSQQSQQQQQLAHQQLSHQQQQALHQQLSHQQQQQQQ 657
                   |:...:..|.:..|.....:.....:|..|.:..|..:..|..|
  Fly   528 -------SEFYGSYAGRNRFHDGYPPEFTPYDAQSFQSMGPQPTAMDQWGA-------------- 571

  Fly   658 QQQQHPHSQLNGPHPHSHPHSHPHSHPHAGQHTHSTIAAAAAAAAASVVSSSSSAVAAAAMLSAS 722
                                :|.|.||                              ||.|
  Fly   572 --------------------AHAHQHP------------------------------AAYM---- 582

  Fly   723 AAAAATAAAAAGGSQSVIQPATSSVSYDLSYMLELGGFQQRKAKKPRKPKLEMGVKRRSREGSTT 787
                                  |::..|...   |||:           ..:.||...:..| ..
  Fly   583 ----------------------STLGLDKGL---LGGY-----------TTQGGVPCFTGSG-PI 610

  Fly   788 YLWEFLLKLLQDREYCPRFIKWTNREKGVFKLVDSKAVSRLWGMHKNKPDMNYETMGRALRYYYQ 852
            .||:|||:||.|:. |..||.||. :...|||.|...|:|.||:.||||.||||.:.|.|||||.
  Fly   611 QLWQFLLELLLDKT-CQSFISWTG-DGWEFKLTDPDEVARRWGIRKNKPKMNYEKLSRGLRYYYD 673

  Fly   853 RGILAKVDGQRLVYQFV--------DVPKDII 876
            :.|:.|..|:|.||:||        ..|::::
  Fly   674 KNIIHKTAGKRYVYRFVCDLQNLVGHTPEELV 705

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eip74EF	NP_730288.1	ETS	786..872	CDD:197710	43/93 (46%)
pnt	NP_524461.2	SAM_PNT-ETS-1,2	179..250	CDD:188879	16/70 (23%)
		ETS	609..693	CDD:197710	43/85 (51%)