DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Eip74EF and Elf2

DIOPT Version :9

Sequence 1:	NP_001014590.1	Gene:	Eip74EF / 39962	FlyBaseID:	FBgn0000567	Length:	883	Species:	Drosophila melanogaster
Sequence 2:	NP_001029081.1	Gene:	Elf2 / 361944	RGDID:	1310585	Length:	591	Species:	Rattus norvegicus

Alignment Length:	352	Identity:	131/352 - (37%)
Similarity:	169/352 - (48%)	Gaps:	88/352 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   562 SSGAGSGGT-----------QPGGPGNPQTPGYLTTSYFNAPTAATAAASQRGTTINGYHSLHQQ 615
            |:..|.||:           |.||...|:.|..:...   .|:|
  Rat     3 SAVVGGGGSVLELSSNGVENQEGGDTVPEFPAVIVEP---VPSA--------------------- 43

  Fly   616 QQQQQQSQQSQQQQQLAHQQLSHQQQQALHQQLSHQQQQQQQQQQQHPHSQLNGPHPHSHPHSHP 680
                      :.:|..|.|.|.:..:..:.|.::.:|:.:.:          |.....:..||
  Rat    44 ----------RLEQGYAAQVLVYDDETYMMQDVAEEQEVETE----------NSETVEASVHS-- 86

  Fly   681 HSHPHAGQHTHSTIAAAAA---AAAASVVSSSSSAVAAAAMLSASAAAAATAAAAAGGSQSVIQP 742
             |:.|.   |..||.||.|   ..:.:.:..|.|.|........|......||.    ...||..
  Rat    87 -SNAHC---TDKTIEAAEALLHMESPTCLRDSRSPVEVFVPPCISTPEFIHAAM----RPDVITE 143

  Fly   743 ATSSVSYDLSYMLELGGF--------QQRKAKKPRKPKL----------EMGVKRRSRE--GSTT 787
            ....||.:.|..::....        ..:|.|..||||.          |:|||:::||  |:||
  Rat   144 TVVEVSTEESEPMDASPIPTSPDSHEPMKKKKVGRKPKTQQSPVSNGSPELGVKKKAREGKGNTT 208

  Fly   788 YLWEFLLKLLQDREYCPRFIKWTNREKGVFKLVDSKAVSRLWGMHKNKPDMNYETMGRALRYYYQ 852
            |||||||.||||:..|||:||||.||||:||||||||||:|||.|||||||||||||||||||||
  Rat   209 YLWEFLLDLLQDKNTCPRYIKWTQREKGIFKLVDSKAVSKLWGKHKNKPDMNYETMGRALRYYYQ 273

  Fly   853 RGILAKVDGQRLVYQFVDVPKDIIEID 879
            |||||||:||||||||.|:||:|:.||
  Rat   274 RGILAKVEGQRLVYQFKDMPKNIVVID 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Eip74EF	NP_001014590.1	Ets	789..869	CDD:278602	69/79 (87%)
Elf2	NP_001029081.1	Elf-1_N	3..108	CDD:403506	28/154 (18%)
		Ets	209..289	CDD:395126	69/79 (87%)
		Herpes_BLLF1	<349..>528	CDD:282904
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	155	1.000	Domainoid score	I4132
eggNOG	1	0.900	-	-		E1_KOG3804
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006321
OrthoInspector	1	1.000	-	-		otm44884
orthoMCL	1	0.900	-	-		OOG6_106781
Panther	1	1.100	-	-	O	PTHR11849
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	9	8.770