DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Eip74EF and ets2

DIOPT Version :9

Sequence 1:	NP_001014590.1	Gene:	Eip74EF / 39962	FlyBaseID:	FBgn0000567	Length:	883	Species:	Drosophila melanogaster
Sequence 2:	NP_001018874.1	Gene:	ets2 / 326672	ZFINID:	ZDB-GENE-050522-552	Length:	439	Species:	Danio rerio

Alignment Length:	242	Identity:	74/242 - (30%)
Similarity:	99/242 - (40%)	Gaps:	52/242 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   667 LNGPHPHSHPHSHPHSHPHAGQHTHSTIAAAAAAA--------AASVVS---------------- 707
            |..|:|||       |.......|....|..|:||        ..|.||
Zfish   185 LTAPNPHS-------SLLRELFQTSDDAALLASAAELPACAKPQLSTVSVRYRSHEFTKNTPQLR 242

  Fly   708 -SSSSAVAAAAMLSASAAAAATAAAAAGGSQSVIQPATSSVSYDLSY---MLELG------GF-- 760
             :.||...|:   ..|..:|......:.||.|.:.......||| |:   :|.||      .|
Zfish   243 TAGSSGEQAS---QESVESAEECVLRSWGSHSSLADTQRVPSYD-SFEEELLPLGLQKHGRSFKD 303

  Fly   761 ---QQRKAKKPRKPKLEMGVKRRSREGSTTYLWEFLLKLLQDREYCPRFIKWTNREKGVFKLVDS 822
               ::.:.::..:|.:...|...........||:|||:||.| ..|...|.||. :...|||.|.
Zfish   304 YVQERNQTQETGRPVIPAAVLAGFTGSGPIQLWQFLLELLTD-STCQSIISWTG-DGWEFKLTDP 366

  Fly   823 KAVSRLWGMHKNKPDMNYETMGRALRYYYQRGILAKVDGQRLVYQFV 869
            ..|:|.||..||||.||||.:.|.|||||.:.|:.|..|:|.||:||
Zfish   367 DEVARRWGKRKNKPKMNYEKLSRGLRYYYDKNIIHKTSGKRYVYRFV 413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Eip74EF	NP_001014590.1	Ets	789..869	CDD:278602	40/79 (51%)
ets2	NP_001018874.1	SAM_superfamily	76..164	CDD:301707
ets2	NP_001018874.1	ETS	332..416	CDD:197710	42/84 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910