DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Eip74EF and Spic

DIOPT Version :9

Sequence 1:	NP_001014590.1	Gene:	Eip74EF / 39962	FlyBaseID:	FBgn0000567	Length:	883	Species:	Drosophila melanogaster
Sequence 2:	XP_006241285.1	Gene:	Spic / 314711	RGDID:	1306272	Length:	250	Species:	Rattus norvegicus

Alignment Length:	248	Identity:	54/248 - (21%)
Similarity:	90/248 - (36%)	Gaps:	77/248 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   640 QQQALHQQL--------SHQQQQQQQQQQQHPHSQLNGPHPHSHPHSH------PHSHPHAGQHT 690
            ||.:|.|..        .|...:.|...:...:..:..|:||...:|:      |...|.....
  Rat    13 QQDSLGQAFEDAFEVLTQHSTGEMQYPPEHRNYMAIINPYPHIRGNSNYCGMLPPTEEPLYDWR- 76

  Fly   691 HSTIAAAAAAAAASVVSSSSSAVAAAAMLSASAAAAATAAAAAGGSQSVIQPATSSVSYDLSYML 755
                         .|.:.|:......:...:....|.|        |.|..|          :..
  Rat    77 -------------GVTNGSADLYLEGSFHQSLQNVAET--------QLVQAP----------FFQ 110

  Fly   756 ELGGFQQRKAKKPRKPKLEMGVKRRSREGSTTYLWEFLLKLLQDREY--CPRFIKWTNREKGVFK 818
            |.||..:||.:                      |:|:|.:.|.:.|.  |   |:|.::.||:|:
  Rat   111 EKGGRGRRKLR----------------------LFEYLFESLCNSEMVSC---IQWVDKAKGIFQ 150

  Fly   819 LV--DSKAVSRLWGMHK-NKPDMNYETMGRALRYYYQRGILAKVDGQRLVYQF 868
            .:  :.:.::.|||..| |:..|.|:.|.||||.|.:.|.:.|: .::|.|||
  Rat   151 FISKNKEKLAELWGKRKGNRKPMTYQKMARALRNYARTGEITKI-RRKLTYQF 202

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Eip74EF	NP_001014590.1	Ets	789..869	CDD:278602	30/85 (35%)
Spic	XP_006241285.1	Ets	122..203	CDD:278602	30/85 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910