DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Eip74EF and Elk1

DIOPT Version :9

Sequence 1:	NP_001014590.1	Gene:	Eip74EF / 39962	FlyBaseID:	FBgn0000567	Length:	883	Species:	Drosophila melanogaster
Sequence 2:	NP_001101529.1	Gene:	Elk1 / 314436	RGDID:	1598663	Length:	427	Species:	Rattus norvegicus

Alignment Length:	85	Identity:	45/85 - (52%)
Similarity:	64/85 - (75%)	Gaps:	1/85 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly   789 LWEFLLKLLQDREYCPRFIKWTNREKGVFKLVDSKAVSRLWGMHKNKPDMNYETMGRALRYYYQR 853
            ||:|||:||:::.. ...|.||:|:.|.|||||::.|:||||:.|||.:|||:.:.|||||||.:
  Rat     7 LWQFLLQLLREQGN-GHIISWTSRDGGEFKLVDAEEVARLWGLRKNKTNMNYDKLSRALRYYYDK 70

  Fly   854 GILAKVDGQRLVYQFVDVPK 873
            .|:.||.||:.||:||..|:
  Rat    71 NIIRKVSGQKFVYKFVSYPE 90

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Eip74EF	NP_001014590.1	Ets	789..869	CDD:278602	42/79 (53%)
Elk1	NP_001101529.1	ETS	4..89	CDD:197710	44/82 (54%)
		PHA03247	<100..427	CDD:223021
		PHA03132	112..>246	CDD:222997
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	116..146
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	166..202
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	226..252
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	300..350
		Sufficient for interaction with MAD2L2. /evidence=ECO:0000250\|UniProtKB:P19419	348..398
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910